I've found that the afterglow of most dissociatives, especially MXE since it lasts for several days, completely relieves most anxiety issues for me. I also have had very few panic attacks since I started using MXE, none when I was actively on it. High doses can also be very spiritual, and I find that dissociatives are easier to handle mentally. The worst times seem like distant memories and the best times are transcendental. Those beautiful moments will relieve almost all the stress I feel if I take a second to close my eyes and remember them. The recreational potential should not be understated of course, MXE is amazing and it's very easy to redose constantly and daily while remaining fairly functional, which may not be a good thing if you have low self control. The best thing about MXE though is that the semi-manic anxiety free afterglow can start to stick around for quite a while, like a learned state, and a very positive one at that. I've been doing it on and off for 6-7 months and it's begun replaced my base mindstate. I'm not a completely different person or anything, but it's helped me recognize the positives and deal with the negatives in a far less stressful way, and my ability to become comfortable in social situations is far greater. All around great.