Not a god damned thing. An animal living away from it's natural environment, eg. a pigeon in a city, a rat in a sewer, or an elephant in a zoo; they are all merely adapting to their surroundings. Humans do exactly the same thing.
Humans were not meant to live in concrete jungles with electricity, television, packaged food and all the rest of that consumerist crap. We simply created that life for ourselves- just like an ant farm will grown beyond the confines of it's aquarium, or a weed will spread to the point where it will out-compete all other species and leave themselves no other resources upon which to survive. Call me a cliche;d pop-culture regurgitator, but we are indeed a virus on our planet, we seek no equilibrium with our surroundings and seek only to exploit all that is available. I say available, and not given, as that is a whole different argument.
Most christians would argue that their god created everything for man to use (except a certain plant which just happens to be evil, and certain male (and female) bodily orifices which ought not meet in close contact) , but most of the rest is there for our use exploitation.
To answer the question- the ability to think beyond pure survival instinct is what separates us from animals. Had Eve, Adam, Mohammed, Pradeep or Chi Duong no eaten from the supposed 'forbidden' fruit' then we would (at least as far as the christian bible is concerned) be no more than eating, shitting, rooting machines- with no sense of morality, philosophy, or oven have the mental foresight to even have this conversation.
I still don't know if it was a good thing.