Have a friend give you one or the othe while he knows which is which and you don't.
This is
single-blind, btw. If you're gonna go through that much trouble, you might as well set it up so the friend is also unaware which opaque pill contains what. They should only know if they gave you "Pill A" or "Pill B" and that info isn't shared until the end of the experiment, nor does the conductor of the test (your friend) know which version is in Pill A nor Pill B. That info is recorded by a third party, or by
you as long as you remain ignorant as to which
Pill, A || B, you took… This "blindness" by both the researcher and the test subject is paramount.
Remember: observing an event causes the observer
to affect the event observed as it causes quantum, probabilistic superpositions to collapse into one, certain position that we can only calculate probabilites for, and this blows my mind
hard, still. Just look at the double-slit experiment w/r/t light somehow existing as both a particle and a wave, collapsing into one or the other depending on how it is observed. Excuse me while I collect my brains that have blown out like a Texas power grid. (yeah yeah, topical humor is lame; I know. Lecturing myself so you don't have to)
you clearly didnt catch my sleight against zephyn.
No, I guess I didn't. Apologies. I'm typically a big fan of sarcasm, but it can be more difficult to detect in written word vs spoken… kinda like our elusive MDDMA, huh? (ahh, ya see what I did there? lol)
at the two hour mark, every time, it noticeably drops.
This reminds me a lot of a batch of
MDE (3,4-methylenedioxyethylamphetamine) synthesized c.2001 by just substituting
nitroethane for
nitromethane in a
MDP2P → MDMA reduction, converting the ketone intermediate into → MDMA or MDE.
Conveniently, methylamine or ethylamine is produced
in situ this way rather than by side-synthesis (Fun facts: methylamine smells like rotting fish and ethylamine smells very similar to ammonia with a touch of that same fishy odor. It's gross
and illegal. Kind of a two-for like that. The reactions are low-yielding and will also create side-products—dimethylamine/diethylamine
and trimethylamine/triethylamine. Here's some literature on the topic in case anyone cares to read about it. It's relevant since this is likely one of the culprits behind side-product MDDMA contamination in black market "MDMA". To wit: it's likely the chemist synthesized their own methylamine but failed to separate it sufficiently from dimethylamine and possibly trimethylamine as well. This person might remain ignorant to the issue while still churning out MDDMA-contaminated product.
https://www.erowid.org/archive/rhodium/chemistry/methylamine.html
https://en.wikipedia.org/wiki/Methylamine
I suppose this is the better thing to be the case instead of apathy, laziness, and greed. Ignorance is slightly more forgivable here.
But so in my instance (well after the statute of limitations)… homemade piperonyl methyl ketone (
PMK aka
MDP-2-P) was the intermediate. Nothing else about the reductive amination I was using needed to be changed. I just subbed CH₃CH₂NO₂ in for CH₃NO₂ (or one could as easily substitute ethylamine for methylamine in this reaction with the same results). This reduction was a method of which Dr. Shulgin was particularly fond, going off of the reported routes to synthesis in PiHKAL. But who knows?
Darrell Lemaire probably had a lot to do with many of those entries in Book 2, he just had to remain uncredited due to the law and maybe his own preference (or both).
But back then, my source for nitromethane also stocked nitroethane, so I figured, what the hell? Why not check it out? MDE I mean, to Pepsi challenge it with MDMA.
In summary, its effects are like an inferior version of MDMA with a shortened duration of action: almost invariably ~2 hrs. Some people, unsatisfied, chased the high, but this was an exercise in futility, as much as chasing the high usually is with MDMA. The difference is: MDMA produces a ~4-hour high while
MDE produces a roughly ~2-hour high. Each drugs' duration is shortened if insufflated.
So to me, MDE sounds incredibly similar to how some others have described the so-called "meh" product and it's difficult to distinguish from MDDMA with GC-MS because they each have the exact same empirical formula, molecular weight, and same basic structure. Yet, I've not seen anything that indicates MDE counteracts MDMA, nor has that been my experience, and I've mixed them, (knowingly and for my own consumption only).
However, there is at least one paper, published in a journal, elucidating some of the pharmacokinetics of MDDMA as being countering in effect to MDMA.
It's going to take a lot of confirming and more tests and theories and whatnot and I still remain skeptical until then, but it's not as implausible as I first thought until I learned of new evidence and pharmacokinetic mechanisms at play in the 5-HT synapse and pre-synaptic storage sites.
