For me it was benzodiazepines due to intensity and length of withdrawal. Constant and extreme anxiety, panic attacks, sleep walking, night-terrors, insomnia, tremors, shakes, elevated bp and heart rate, terror and just feeling like I was going to lose my mind or have a seizure. Buprenorphine (Suboxone/Subutex) withdrawals are pretty horrible just due to how long they last including the PAWS symptoms, but the level of intensity of the physical withdrawal is less than heroin or other full-agonist opiates, IME. Alcohol was horrible because it was incredibly intense and frightening, thinking I was going to have a seizure or heart attack. Same withdrawals for me as benzos, only shorter lasting and more intense. Luckily they have benzos to aid the alcohol withdrawal, but for benzo withdrawal you can only taper, as there is not an effective medication for the withdrawal like benzos are for alcohol. Amphetamine withdrawal wasn't too horrible for me because I was young (17 at the time) and I had only used for 2 years (although everyday, basically) and I used mostly orally, sometimes nasally. The withdrawals consisted of depression, lethargy, increased appetite, increased sleep, tiredness and the worst was the boredom and cravings. I didn't abuse them hard enough to have a long-lasting amphetamine psychosis (thankfully). The major problem with amphtamines, however, is that I have never gotten used to life without them. I used them to treat my ADHD and self-medicate my depression and mood disorder. I have never gotten used to life without them and I now need some other type of drug to motivate me to do anything, any kind of work or even getting out of bed has to be motivated somehow and in general it's with drugs. Now I only use bupe, which I do not get a high from and only occasionally get a "glow" or mood-lift. So, I am pretty depressed at the moment because I don't really have anything to motivate myself. I used to smoke a lot of cannabis, but I am not in a good place in my life right now, mentally, and whenever I use cannabis I feel really guilty, anxious and depressed by dissecting and over-analyzing my life and not being able to hide and ignore my problems and emotions. Benzos and alcohol were extremely difficult to get off of but after 6 months, I don't really miss them. If offered I wouldn't be able to say no, but I am not really out searching for them. My cravings are generally for opiates, even though I take bupe daily as a maintenance drug. I just wish the bupe worked like it did in the beginning, before I jacked up my tolerance by still using IV heroin on occasion. I also get really bad cravings for meth/amphetamines, but I can't enjoy them without benzos, or a combination of benzos and alcohol for the the comedown. So, being off alcohol and benzos, I stay away from speed.