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Stimulants What is happening to me?

CYP2D6

Greenlighter
Joined
Apr 27, 2012
Messages
17
Hello,

So pretty much I've had some issues lately with my prescribed Dextroamphetamine. I've been searching the internet far and wide for the past few days for hours on end and I can't come to any definitive conclusion.

Firstly let me just paint the picture for you. I've been using D-amp for my ADD for the past ~2 months or so and haven't experienced anything other than positive effects besides the typical appetite loss, insomnia and unpleasant comedowns.

However the other day, everything took a turn for the worse:

Day 1: Took my prescribed dose as usual but that night I preceded to say 'fuck it' and stay up all night to finish an assignment for school due the following day. I took around ~50-60mg over the course of the night and made sure to drink plenty of water and eat plenty of healthy foods.

Day 2: Went to school after pulling an all-nighter and used around 40mg to stay awake and function. I felt pretty normal other than being slightly delirious; although I don't think that's important. That day I knew that the come-down would be absolutely horrible so I managed to score 20mg of oxycodone to help. I used about 50mg of DXM and copious amounts of grape fruit juice to potentiate the oxy. The oxy hit me like a freight train - probably because I hadn't used in 5 months, i spend that afternoon nodding in absolute bliss.

Day 3: I woke up after about 8-9 hours sleep and for some reason decided to abuse my d-amp. I took around 50mg and went to school. for the first ~2 hours I felt fantastic and on-top of the world; how mistaken I was. All of a sudden I was hit with an intense bout of nausea and dizziness. I left school early and came home, I researched my symptoms and came to the conclusion that I was suffering an opiod-hangover to which I took 50mg of promethazine to combat my nausea.

After the drowsy effects of the prometh took its toll, this is where my problems began, however I doubt it was the prometh - rather just a coincidence. I felt, what can be described as 'strange' - just like a 600mg DXM trip, I felt:

-an immense brain-fog and dizziness
-confused and dazed at times
-as though I was disconnected and I was floating.
-my body was quite numb
-I had 'tunnel vision', in that anything that I wasn't focusing on was blurring and strange.
-my hearing was also a bit dulled
-cold flushes

It wasn't exactly dysphoric or nightmarish but it was unpleasant after a while and I just wanted to feel normal again. Stupidly I took 20mg of d-amp hoping that it would cure my symptoms, but I felt the same, maybe even slightly worse.

Anyway, I managed to maintain some basic eating habits and get some sleep.

Day 4 - Awaking after a hefty ~11 hour sleep I felt much better - almost normal, however the effects started to come back gradually and I experienced a panic attack (I'm fairly accustomed to them due to an anxiety disorder so this didn't bother me too much). That night I went to a party and took 20mg over the course of the night along with a lot of alcohol. A point to note is that when I took my first dose of the night (10mg) I felt quite nice although weird with a continuing brain-fog. I also had fully dilated pupils and a compulsion to dance.

Day 5 (today) - I woke up with no hangover but maintained this ongoing brain-fog which has made even the most trivial tasks quite thought-demanding. I took 10mg of d-amp to study but that proved useless and instead made my brain-fog more intense and got a slight body buzz.

I have convinced myself of having (although I'm 99% thats not the case): serotonin syndrome, liver failure, hyponatremia, permanent brain-damage (still thinking that :( ) so I need a personally catered response in order to be certain.

Obviously the contuniuing usage of d-amp isn't helping and a week's break is in order but I'm scared this will all happen again after I resuming.

I've started to think that maybe I've depleted my dopamine so i've been taking Vitamin B's, Magnesium, zinc (anything that might help my brain)

Thank you for taking your time to read this.

If anyone has experienced this or something similiar I'd like to hear it! The main thing I'm looking for is something conclusive and ways to prevent/cure it.
 
How much dextromethorphan do you use, bro, out of curiosity? I used to use a lot, and I got similar symptoms.

If its any consolation, I'm highly doubtful it's Serotonin Syndrome. I also doubt liver failure, unless you have CLASSIC liver failure symptoms other than those posted. Hyponatremia is a possibility, especially with all the increased sweating from amphetamines. Need to get that checked through a doctor.

As for brain damage, there'll always be some with abuse of this drug, though you can mitigate it. That said, it's probably possible to ameliorate the damage, it's not necessarily permanent.

Have you looked into dissociative disorder? Depersonalization/derealization?

I don't know for sure, but I do know that I got symptoms that were nearly identical when I was coming off DXM doses.

PM me if you want to talk farther, I am online and will likely remain so. At the very least, I can provide an outlet for conversation about what you're experiencing, if you want to chat in a real-time client like Skype or something. Just PM me.

In the mean time, go to a doctor, and tell him what you're experiencing. I doubt such low doses of amphetamine (on their own) are causing this, however.


Also, you really shouldn't be combining amphetamines with dextromethorphan. Just be aware that it's highly recommended you don't do that, for myriad reasons, at least in any serious amounts. From my readings, DXM + stims equals a very dysphoric/unpleasant comedown/hangover.
 
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Thanks for the reply buddy.

I very rarely use dextromethorphan as I'm not too keen on it's effects. I've probably used it twice for 'recreational' purposes at about 500-600mg. Otherwise I use it on the odd occassion (every few months) at a low dose (30-60mg) to potentiate opiates.

Yeah, I too am doubtful of SS and liver failure I was just worrying myself haha. I'm a bit scared to see a doctor and I simply don't have the time, would you think its extremely important?

Regarding the dissociative disorder, that was the first thing I found after googling something like "i feel disconnected from reality" or something and the symptoms resonated with me at the time although I don't feel like that anymore, just more of a head-fog.

I was also surprised at how such a low does of amps caused such a drastic effect, that's why I felt the need to make this thread. I've heard of people staying up for days on end using meth in much higher doses and not having any problems except for a shitty come-down. And considering I have a fairly decent tolerance and experience with a lot of substances, this is quite stressful.

How long did your symptoms persist and how frequently did they occur? thanks again for the reply man, appreciate it!
 
Thanks for the reply buddy.

No problem, I'd appreciate the same from you/others.

I very rarely use dextromethorphan as I'm not too keen on it's effects. I've probably used it twice for 'recreational' purposes at about 500-600mg. Otherwise I use it on the odd occassion (every few months) at a low dose (30-60mg) to potentiate opiates.

Probably not the culprit, then, almost assuredly.

Yeah, I too am doubtful of SS and liver failure I was just worrying myself haha.

Don't worry, bro, we've all been there. I certainly have.

I'm a bit scared to see a doctor and I simply don't have the time, would you think its extremely important?

I think it's very important if the symptoms continue or worsen. You could refrain from mentioning the amphetamine use to the Dr., if you feel better, as it's unlikely to be the culprit and the doc might find something else unrelated.

Regarding the dissociative disorder, that was the first thing I found after googling something like "i feel disconnected from reality" or something and the symptoms resonated with me at the time although I don't feel like that anymore, just more of a head-fog.

It could have been temporary derealization. That's what DXM did to me, to give me my symptoms.

I was also surprised at how such a low does of amps caused such a drastic effect, that's why I felt the need to make this thread. I've heard of people staying up for days on end using meth in much higher doses and not having any problems except for a shitty come-down. And considering I have a fairly decent tolerance and experience with a lot of substances, this is quite stressful.

I can imagine your state of worry. And, yeah, I've personally stayed up for over a week, and haven't got symptoms like yours solely from stimulant use.

How long did your symptoms persist and how frequently did they occur? thanks again for the reply man, appreciate it!

They generally lasted 2-4 days after DXM use, not stims. It came and went in waves while it was present.

I'd say if your issues continue for over a week, it's definitely Dr. time, bro. But don't panic. It rarely helps, and if it does, it's too late anyway. ;) Remain calm and continue to analyze your symptoms until you're sure they are not a concern, or they are diminishing in severity. In the mean time, try to deal with them positively. I always found benzodiazepines helped the symptoms I felt (the ones similar to yours), though that's an addictive can of worms to open. You should also try refraining from stimulant use for a few days, see if anything changes.

btw: My Skype name is "Druidus-Logos". Feel free to add me.
 
My advice is to refrain from stimulant use for a few days and let yourself reset. Dexamphetamine is easy to take too far too fast.

If your symptoms don't improve after a few days rest from stimulant use, its probably best to speak to your doctor.
 
Yeah, I'll probably refrain from stimulants for the next week as I'm going on a road trip for a week with some buddies tomorrow, I might bring some amps with me but only a small amount incase of severe tiredness.

My symptoms seem to be diminishing and will hopefully be gone soon, and will make sure to see a doctor if they persist or if they occur again.

Once, again cant thank you enough for your insights, i don't have skype as of yet but will make sure to PM you in the next few days to let you know how I'm doing, have a good night/day man!

If anyone else has anything to add please do!

My advice is to refrain from stimulant use for a few days and let yourself reset. Dexamphetamine is easy to take too far too fast.

If your symptoms don't improve after a few days rest from stimulant use, its probably best to speak to your doctor.

Will do! 10mg once or twice in the next week cant hurt or should I just cut it all together?
 
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If possible, cut it out altogether. I am a pretty regular user of dexamphetamine myself and know how tempting it can be to take on long drives...but try and keep your dosage as low as you can if you can't cut it out altogether.

I know you've mentioned this already but make sure you're eating enough food and drinking enough liquids (including electrolytes). Amphetamines cause dehydration. Pick up some Gatorade next time you plan on taking Dexedrine. Vitamins make a world of a difference as well. Don't just take them when you're on amps, take them during your break. Vitamin C, a B-vitamin complex, fish oil, vitamin D, and last but certainly not least magnesium help a lot.
 
^Pretty much.

I've been using speed (you gotta remember that massive prescription rates for amphetamine ADHD medications means they are extremely cheap and extremely available on the black market as well) on and off since 2006. In around 2008 or 2009 I found a source for Dexedrine (vs. the more common Adderall) and have stuck with that since. Unless you are really careful, amphetamines will seduce you. I'm sure the OP knows this already. I've had one high dose amphetamine experience (and the resulting psychosis) and I never want to repeat it again.

OP, I've been there. It will get better. Take care of yourself and remember that amphetamines are a very powerful class of drugs.

<3
 
Drop it all is my advice. Back when pharm speed was first ubiquitous in the 50s and 60s it made everyone sick and was eventually reviled by most drug users as a dangerous substance that had terrible effects on mood and personality. Then after a few years had passed and people had forgotten history Big Pharma and Psychiatry managed to re-brand it in the US and now everyone is diagnosed with ADHD and has been on prescription stims since childhood. Many experts outside of the US view all of this as completely insane, but even if ADHD is real and stims help over the long term (I find both propositions ludicrous and have seen nothing but quackery and poor results watching people over the last couple of decades but am obviously in the minority around here), recreational use of amphetamines and these other drugs is absolutely unhealthy, dangerous, and generally leads to schizzed out mental states. Obviously this board is full of recreational speed users but most are relatively young and have yet to see what happens over time. It's a downward spiral - my advice would be to stop all amphetamine, opioids, and disassociatives now. Good luck to you in any case...

"Now we return you to your regularly scheduled enabling...." ;)

I share you skepticism even though I have 'textbook' symptoms of ADHD but this d-amp has really helped me in therepuetical doses. I have calmed down on my drug use, being 17 and all though I will still experiment from time to time but thanks for your advice :)

If possible, cut it out altogether. I am a pretty regular user of dexamphetamine myself and know how tempting it can be to take on long drives...but try and keep your dosage as low as you can if you can't cut it out altogether.

I know you've mentioned this already but make sure you're eating enough food and drinking enough liquids (including electrolytes). Amphetamines cause dehydration. Pick up some Gatorade next time you plan on taking Dexedrine. Vitamins make a world of a difference as well. Don't just take them when you're on amps, take them during your break. Vitamin C, a B-vitamin complex, fish oil, vitamin D, and last but certainly not least magnesium help a lot.

I will try to cut down completely for the next week. I've been taking Vit.B and Magnesium daily for the last few days now and drinking alot of white tea. I'll need to pick up some Vit.C though as I have heard nothing but great things about it.





^Pretty much.

I've been using speed (you gotta remember that massive prescription rates for amphetamine ADHD medications means they are extremely cheap and extremely available on the black market as well) on and off since 2006. In around 2008 or 2009 I found a source for Dexedrine (vs. the more common Adderall) and have stuck with that since. Unless you are really careful, amphetamines will seduce you. I'm sure the OP knows this already. I've had one high dose amphetamine experience (and the resulting psychosis) and I never want to repeat it again.

OP, I've been there. It will get better. Take care of yourself and remember that amphetamines are a very powerful class of drugs.

<3

I have am very familiar with the seduction of amphetamines and have learnt to control my abusive tendencies and will continue to after this experience! Normally I'm quite introverted but not because I lack the confidence, more-so because I find 99% of people are completely boring to talk to and the amp actually makes everything seem intrinsically interesting which is the main seducing component of them!

I've always underestimated amphetamines but these past few days have shown me their true capabilities so I will not look at them the same way anymore!

thanks for all the help guys <3 you all, stay safe.

p.s: not that it's important but I'm from aus and the only thing we get here is generic "Dexamphetamine Sulphate 5mg tablets" that come in bottles of 100.
 
Sounds like you should stay well clear of dxm to me, i Personally think it's awful stuff. I cant comment on what i think your symptoms are caused by but i do think if you suffer from anxiety you should really consider stopping your stimulant use altogether, its fighting fire with fire. Your liver is fine so stop worrying about that. Have a break and give your body/brain chance to recover.
 
They can only prescribe it to you in bottles of 100x 5mg tablets?

Wow man. In the U.S., 10mg XR capsules and 10mg IR tablets are a lot more common than the 5mg IR tablets...but those little guys were the first dosage forms of dexamphetamine I experienced too.
 
how many times in your post did you state "i abused my dextroamphetamine"


it starts with you abusing your prescribed medication, to abuse your body by not sleeping...

you're doses are not prescribed levels, 20mg oxy potent can be more than enough, and 50mg promethazine is unnecessary?
 
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