Something like Ghost In The Shell except we'll be spending more time in virtual environments than "reality" which will become pretty much become an entirely meaningless pursuit once we figure out it's possible to have the same experiences virtually thanks to the major advances in biotech and computing tech.
Right now there are teams making all kinds of breakthroughs in connecting digital information with human brains. So far it's just about better robotic arms but very soon we will have the technology to put a chip in our head that connects to our brain as a calculator and we will get it to stay competitive with all the people who get it right away and we will become used to spending time in virtual environments. These things are completely certain, the uncertainty lies in just how digital we become and whether or not we will see a point in holding onto our corporeal forms.
IMHO trying to frame life in a hundred years in a human context is futile because we will be beyond that. In the past we have been chained to natural evolution so change was so gradual it was imperceptible. We are now forging our own evolutionary pathways and it may lead us down more than one path and split us into different "species", so to speak, but it will be something beyond what we can even imagine. That's especially true if the chip-in-our-heads deal comes within the next 20 years, if you pay attention to tech news at all that seems to be a stretch it's likely to happen even sooner.
Don't you ever feel like the information available to us now is overwhelming? Well then, you will be one of the first to get a chip in your skull that can process information to the tune of billions of floating point operations per second. That's like a billion people on a billion calculators doing a billion unique calculations at once. That's insane. That's inconceivable. That's already in the pipeline. Just imagine how fast progress will accelerate once we have that capability. Or at least, sleep on it for now and try to imagine it after you get chipped. It'll be a lot easier to do then.
Nice post

Makes you wonder what could be possible when we start to tune people into super evolved Einsteins and what a team of those people could come up with. This might turn out great, but it might also turn out quite nasty in the wrong hands I can imagine. This is an interesting time indeed when you look at it from a technological viewpoint.