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  • BDD Moderators: Keif’ Richards

Misc What are your guy's experiences with antipsychotics?

JEO

JEO

Greenlighter
Joined
Sep 29, 2025
Messages
3
Location
Central Point, Oregon
I'm a schizophrenic, and I'm just now repairing from all my substance use... I'm on wellbutrin 75 mg 1x morning, and olanzapine 5 mg 1x night. Thinking of switching to quetiapine (seroquel) so Im just on an antipsychotic and nothing else... I just hope its enough.

What are your guy's experiences?
 
I was on Seroquel for years for the same ,I had a very rough time with it. Worsened my already irratic depression and changed my personaltiy to even weirder than it was. I gained a shit ton of weight too. Sure it quieted the symptoms,but the side effects are junk! If you well managed of current meds ...stay there! But this is merely my experience! Good luck,lemme know what you decide~! Cheers
 
Jaysoul said:
I was on Seroquel for years for the same ,I had a very rough time with it. Worsened my already irratic depression and changed my personaltiy to even weirder than it was. I gained a shit ton of weight too. Sure it quieted the symptoms,but the side effects are junk! If you well managed of current meds ...stay there! But this is merely my experience! Good luck,lemme know what you decide~! Cheers
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Thanks for the input... I've been on it all, and personally, I actually tolerated seroquel the best compared to the SGAs... Olanzapine and risperdal seem to make me extremely depressed and sedated, but, of course, I need to trial the quetiapine again to see if its the same as before, because I was still using nicotine products, as well as kratom
 
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Haloperidol: neuroleptic malignant syndrome
Thorazine: Ok.
Quetiapine: helped me sleep
Olanzapine: Worked the best. Stable moods and mental state. no hunger/weight issues
Uzedy (risperdal depot injection): current. feel more stabilized. hunger/weight issues. no diabetes, though.
 
I don't have schizophrenia nor suffer any disorder requiring antipsychotics, but the only antipsychotic I would ever willing put in my body is seroquel (at low doses).

I once took some olanzapine in the middle of severe opioid withdrawal hoping it would help, and I only felt more horrible.
 
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Like all medicines antipsychotics have pros and cons but ultimately it's up to the user to weigh these up and decide for themselves.

They are currently the best tools we have for psychotic illness' such as bipolar and schizophrenia. On the other hand they are overprescribed for a myriad of off-label indications for which the evidence of their efficacy is poor. Insomnia, anxiety and depression are now all routinely treated with anti-psychotics without much care for what the literature says.

There is also a lot of discussion about brain atrophy, neurotoxicity and other forms of toxicity. We know for a fact that antipsychotics shrink the brain by reducing grey matter volume in animal models and have correlative data it does the same in humans. At what dose? What AP? How long? Who knows!

I dunno, they have their place in medicine, especially for folks who wouldn't know what day of the year it was without them.
 
I use chlorprothexin in opioid WD but i don't recommend this if u don't have any benzodiazepines or something against sizures or muscle twitching.
 
Had experience with Thioridazine over 30 years ago from a psychiatrist who thought it would curb my enthusiasm for experimenting with drugs. Was in my early 20's at the time.

So, totally ignored the ADHD diagnosis, that was so obvious, he just "winged" it.

So, no regrets, as I gained experience.

Bottom line is, if you need these meds for serious symptoms ( basically hospitalized supervision or constant home care), I would avoid at all costs.

HOWEVER

In your case, I would speak to your psychiatrist about switching, but as a previous member posted, they are content with Zyprexa (Olanzapine), maybe a dose adjustment is all that is needed.

I am not a doctor and and only sharing my opinion based on previous first hand experience and current, "hands on" experience, with a relative using low dose seroqual (off label) for sleep.

I don't agree with this but considering many other factors, I understand why the psychiatrist is using them for this patient..

But that is another story for another time.


Good luck.
 
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I should have mentioned that I am having side effects from the olanzapine... It causes me a lot of problems, and Im gonna be happy if I can switch to seroquel. The olanzapine works, its just not the best that I know there is.
 
These medications have a time and a place. I take 2mg Risperidone twice a day and .1mg clonidine for bipolar and anxiety prescribed to me by a psychiatrist. The side effects of skipping a dose can be worse than my actual disease. There’s a whole Coming off Invega series of threads in The Dark Side. Overall these meds can help even if they suck they still help stabilize patients and they keep me from hallucinating
 
They do have a time and place -- truly "A doctor should decide and a second opinion sought after" territory. I know they use Seroquel to basically turn the psych ward into 'thorazine zombies' and do the same to Alot of people that have an "edge" but I would not consider nearly schizophrenic.

**Sidenote - Many doctors have confided in me that there is often a thin line between 'schizophrenic' and 'something beyond explanation' *** You know 98/100 schizophrenic but those other two...
 
My experience in general is institutions using them to shave IQ points off anyone they damn well please. They also treat some people that truly need them - I have/had a cousin that is schizophrenic and I want him on his damn seroquel.

Post Script -- He is scary intelligent and believes in/sees supernatural type shit. (Whether that is teathered to reality at all is a different question ... not that I have seen))
 
If you're not a vegetable, the antipsychotics will turn you into one. Don't take them unless you're a vegetable. Who knows what it's doing to the brain. The people who have prescribed these things to everyone will be the last to admit it if it's causing some harm.. because they don't need the legal trouble. They'll blame it on you if you go down hill. "Progression of X illness"
 
My experience with antipsychotics is when they are needed they serve their purpose, however, prescribers assume these drugs are a full time commitment and do not encourage coming off them without replacing them with another antipsychotic.
Question everything.
 
i think anti-psychotics are going to bring most people's lives down.. most people don't like the lack of sex drive. they can be relaxing, but none i've tried really have the cleanest feel. a lot of them cause tardive dyskenesia which tends to make taking them nerve wracking... i don't think they are really the best to be on unless you can't really get by with out them like you keep getting in trouble because of delusions, or you are plagued by unwanted voices. i think they help schizophrenic and autistic people not act out as much if the root of their problem stems from being hyper and not thinking. i'm assuming they slow people down and help them evaluate their situationss. taking AP's never got rid of any of my delusions however with constant acceptance that i have schizophrenic, with out them i can get through reality not being too paranoid of people. a lot of the time i just assume that i'm probably being surveyed by people in a local gang that do stuff with the CIA, but i don't really care and just ignore all that shit... every time i take meds i think i'm still being gang stalked. i thought there was like an agenda to force people to take meds, or me particuarly, but they always just let me go off meds right when i get out of the hospital. like at the first appointments, even after being hospitalized like 5 times, they always just start to ween me off them at the first appointment. after a few months i'm off the meds completely.


i think if there were more support for schizophrenic people, then they would need meds less. like they put the housing for mentally ill/disabled people right next to a bar and convenient store and liquor store parking lot where there is a ton of noise. that shit sets of schizophrenia. RFK was talking about wellness farms. if schizo people were willing to accept they needed help, they could get by on farms a lot better than just being medicated and forced to live in the city i'm going to guess. like some people schizophrenia is a lot more severe than others and it's not just hearing traffic or people at the bar that will set off their hearing annoying voices, but i've talked to a lot of people where this is the case.. schizophrenia can just be like hardcore delusions about some pretty weird stuff though. in some cases medicating and forced medication can stop the delusions. i'd think more people would act out when being forced into medication though. it can be unpleasant though, and i don't really see it as an effective way to stop the delusions.. ime it can only stop the audio or visual hallucinations. some of them work better than others with stopping the voices from being heard outside your head. like i could definitely see medicating if you heard voices and wanted to safely drive. that shit can get over whelming in situations like that.
 
it's not just hearing traffic or people at the bar that will set off their hearing annoying voices, but i've talked to a lot of people where this is the case.
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Now this is interesting. I've had acoustic hallucinations from skipping nights on dissociatives and always thought they were noise somehow misinterpreted by my brain. The voices were quiet in a peaceful room but loud out on street. Recovered naturally without antipsychotics but tried a few and those were altogether awful.
Edit: I also heard whispers and sometimes screams in white noise, like running water or a fan.
 
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It is hard to find the right medicine. For me they work for certain period of time, do what they are going to do (ceiling effect), and they seemed to re-program my brain & I have had to take it from there. I have Schizoaffective disorder and Borderline Personality Disorder. The following meds have helped me the most :

-- Seroquel
-- Haldol
-- Clonidine
-- Ativan
-- Busbar
-- Zoloft
-- Invega
-- Pentobarbital
 
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