Misc Wellbutrin in recovery. Great for coming off meth, but stops working after about 8-9 months, how to switch it up?

[soundsystem00]

All meds stop working, but the beauty of anti-depressants is that they work long term. The best benefit of Wellbutrin is that there are no frustrating side effects.

I loved being on Wellbutrin. There was a deep satisfaction, and I remember having that "itch I didn't know I needed scratching" feeling, and as an addict, that is a very good feeling to have when you are trying to get sober. It wasn't a recreational high, a buzz, or even any fun, but it was enough to stay off drugs for over a year. Well after a while, it did finally stop working as well. I know when this happens with SSRI's, the doctor will usually just find a similar medication that has almost an identical molecular structure and this will be just enough to keep the effectiveness of the original medication. I looked for similar pills to Wellbutrin and didn't find much right off the bat. I was wondering if anyone knows of some good things I could switch to after getting back on Wellbutrin? I am thinking about eventually getting back on it as I am intending to get off Meth, Benzos, Alcohol and other addictive substances.

Thank you all! Have a nice one!

 

[theangryflower]

Wellbutrin is an NDRI----so anything that falls under that category---it isn't an SSRI. With that said, there is a body of research that says Wellbutrin & Naltrexone paired together is effective. I am starting it soon

 

[theangryflower]

You can fuck the naltrexone right off, it's just there to block positive effects and stop use, it makes the user feel like shit, is expensive, doesn't address any underlying reasons for use.
Can fuck it off completely unless you want to do the whole drinking without getting drunk or shooting junk without getting high. Save yourself the money and time, just don't drink or shoot junk mate.
It's just an mu-opioid antagonist or whatever them cunts who read textbooks call it. Fucken pointless mate.
Never understood cunts who needed to stop the positive effects of their gear. Like who fucken came up with that idea, "boo hoo poor me my gears making me feel better well better stop that feeling better and keep doing the gear", Some deluded pharmaceutical executive off his tits on coke listening to only the sniveling junkies no doubt.
There saved ya a few weeks of fucken around and hundreds of bucks.
No worries cunt you have a fucken ripper of a week!

It also helps with cravings when paired with the wellbutrin. I am going to try it----as I am quitting drinking & speed. I don't shoot it lol---just snort, but I am ready to quit and move on with my life.

 

[soundsystem00]

You can fuck the naltrexone right off, it's just there to block positive effects and stop use, it makes the user feel like shit, is expensive, doesn't address any underlying reasons for use.
Can fuck it off completely unless you want to do the whole drinking without getting drunk or shooting junk without getting high. Save yourself the money and time, just don't drink or shoot junk mate.
It's just an mu-opioid antagonist or whatever them cunts who read textbooks call it. Fucken pointless mate.
Never understood cunts who needed to stop the positive effects of their gear. Like who fucken came up with that idea, "boo hoo poor me my gears making me feel better well better stop that feeling better and keep doing the gear", Some deluded pharmaceutical executive off his tits on coke listening to only the sniveling junkies no doubt.
There saved ya a few weeks of fucken around and hundreds of bucks.
No worries cunt you have a fucken ripper of a week!

Dude man, I am on Suboxone and Naltrexone has put me into these nightmarish withdrawals twice! It was insaneeeeeee.

thank you for the NDRI info that will help shall I ever get back on Wellbutrin.

 

[soundsystem00]

Yeah mate if someone put you on 50mg naltrexone pills to help with cravings while on Suboxone they really shouldn't be prescribing that to you as a patient and personally I'd run from a health care provider that ignores such an obvious interaction between treatments and prioritises "reducing cravings" over your wellbeing. Doctors not meant to harm their patients like that and should know better.

If you've got bupe 8mg with 2mg naltrexone the idea behind the formulation is that a low dose of naltrexone isn't going to be orally active but is put in there to lower abuse risk (the naltrexone is added specifically to stop IV self administration by sending the user into precipitated withdrawals) so if it happened after shooting/boofing ya bupe just be aware that it will happen before self administrating and stop the process and take sublingually in future, if it for some reason is happening when you take sublingually as prescribed it'd be worth talking with your doctor about getting naltrexone free bupe tablets if they still prescribe and manufacture them, they'll probably not be very cool about it due to potential abuse risk. not sure if that's relevant to you mate. Have a bloody ripper of a day mate!

whats a good info for stim script on bupe?

 

[Allylbenzene]

Do you really need the bupe? Can you taper off it?

Thought i'd give some background/context on how the stimulants Wellbutrin (bupropion) and meth work which might help OP or others see what's going on.

Wellbutrin mainly increases noradrenaline (+weakly increases dopamine). Noradrenaline is part of the stress response (aka fight-or-flight) and is a factor in anxiety. Increasing noradrenaline will have stimulant effects. If your cortisol stress levels are already high adding more noradrenaline won't help and probably isn't a good idea.
Meth strongly increases noradrenaline and dopamine. It's also an MAO inhibitor, dopamine D2 agonist and alpha-2 adrenergic agonist. (according to wiki)

Drugs that have the "alpha-2 adrenergic" property are used to reduce opioid/benzo withdrawls (eg clonidine, agmatine).

Agmatine is otc and helps reduce withdrawals + repairs things (via neurogenesis).
Theanine should also help, it's relaxing, stops the stress response and helps repair things (via neurogenesis). Best used in the evening.
Those 2 should help to 'reset' drug tolerances (in part via NMDA antagonism, BDNF and GDNF).

As for the stimulant bit:
- Coffee - metabolic stimulant & boosts dopamine
- Theacrine - relaxed version of caffeine, boosts dopamine
- Hordenine - increases noradrenaline, direct dopamine D2 effects, weakly increases dopamine (more info)

That pretty much covers what Wellbutrin and meth do but in a more sustainable way.
All these things I mentioned are otc and fairly cheap.
If you're gonna try coffee read this for easy tips on how to maximise it's benefits and avoid bad reactions.

Symptoms to expect when you do coffee right are calmness, focus, motivation, warmth, and stable energy.

 

[Allylbenzene]

Different studies in different cinditions and use styles show different results.

I'd agree with this, there's also the motivation for pharma companies to sell more drugs by generating more possible uses.

Looking purely at the psychoactive effects of wellbutrin & naltrexone, they do have real effects and can be helpful.
Wellbutrin gives the adrenaline rush (minor dopamine) whilst naltrexone blocks opioid-reward.
But imo there are more efficient solutions that don't require prescription drugs (see my previous post).
Slow-release Wellbutrin is convenient, but theacrine, caffeine and hordenine are OTC and can be dosed in small amounts throughout the day.

Also, naltrexone has effects beyond the opioid system which contribute to its theraputic benefits. (Low doses of naltrexone range from 0.5mg to 5mg)

Part of the solution is to address the reason why someone is self-medicating with a drug in the first place.
Interpreting drug use as self-medication for unacknowledged health issue(s) is more useful than seeing it as a mere "addiction".
"Addiction" tends to involve stigma and prejudice but health issues are more "approachable".

 

[theangryflower]

What a load of crap it their choice to use. They just need to hit rock bottom. Tent cities are recovery centres in disguise. /S

I bet you are a riot at parties.

 

[theangryflower]

/S is sarcasm

My point still stands