GaumarolBostich
Bluelighter
- Joined
- May 31, 2026
- Messages
- 50
Since I am sweeping Reddit subs frequently and dosage is one of the most frequently asked question:
Is weight really the or one of the most important factors for dosing MDMA?
I know that there is some dosage calculators and in almost every discussion someone throws in a key like X,XX mg x kg or lb. Now what is confusing me:
1. In any dosage recommendation on harm reduction sites there is a max dosage recommended. That doesn't align with an overall rule dosage by weight. Why should it be outruled just by crossing a fixed amount?
2. Dosage is about concentration in blood (and then ability to cross the blood-brain-barrier) as far as I know. Yes the amount of blood is aligned with weight, the more you weigh, the more blood. So a) are we talking in absolute % concentration of the substance and b) is the composition of the blood important meaning drinking a lot will spoil the rule?
3. I don't know any pharma medicine that is prescribed by kilo. Maybe the doctor will take your overall weight in account, but I have not seen it mentioned on any package leaflet in the pill box.
I would say that a extreme lean or heavy person should adjust the dosage but there is a broad span of body types which should hit the dosage. But this is pure feeling.
Side quest: A lot of 4-MMC users adapt the MDMA rule by weight. I personally do not see that. My wife is leaner than me and needs more of that substance. This is absolutely no data base of course.
Thoughts or facts? Rost me.
Is weight really the or one of the most important factors for dosing MDMA?
I know that there is some dosage calculators and in almost every discussion someone throws in a key like X,XX mg x kg or lb. Now what is confusing me:
1. In any dosage recommendation on harm reduction sites there is a max dosage recommended. That doesn't align with an overall rule dosage by weight. Why should it be outruled just by crossing a fixed amount?
2. Dosage is about concentration in blood (and then ability to cross the blood-brain-barrier) as far as I know. Yes the amount of blood is aligned with weight, the more you weigh, the more blood. So a) are we talking in absolute % concentration of the substance and b) is the composition of the blood important meaning drinking a lot will spoil the rule?
3. I don't know any pharma medicine that is prescribed by kilo. Maybe the doctor will take your overall weight in account, but I have not seen it mentioned on any package leaflet in the pill box.
I would say that a extreme lean or heavy person should adjust the dosage but there is a broad span of body types which should hit the dosage. But this is pure feeling.
Side quest: A lot of 4-MMC users adapt the MDMA rule by weight. I personally do not see that. My wife is leaner than me and needs more of that substance. This is absolutely no data base of course.
Thoughts or facts? Rost me.
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