Mental Health Want to try lamotrigine but I'm a little scared

[AlphaMethylPhenyl]

I don't think any hypertensive crises have manifested with emsam, at least none that I'm aware of. That said, it's a pretty powerful medication. Under a learned doctor's order, sometimes MAOIs have been combined with tricyclics or stimulants.

I read somewhere on the internet that the diet really only applies to one in four people, but it was just hearsay. Your doctor would know best.

 

[paranoid android]

I don't think any hypertensive crises have manifested with emsam, at least none that I'm aware of. That said, it's a pretty powerful medication. Under a learned doctor's order, sometimes MAOIs have been combined with tricyclics or stimulants.

I read somewhere on the internet that the diet really only applies to one in four people, but it was just hearsay. Your doctor would know best.

The diet for old MAOI's is real for the most part but they have found out lately due to new interest in these drugs that it need not be as restrictive as it once was. Id probably try Parnate if i had unipolar depression but it get's a bad rep for Mania. Though a anti-psychotic might prevent that.

 

[jammin83]

Not very good for bipolar depression you think? Or just because of the mania issue? Can't really take APs anymore after I get through this withdrawal. Went bad on me. Never really responded well to many mood stabilizers besides zyprexa. Stuff worked great when it did, but has totally fucked me off getting off of it. I've heard good things about MAOIs but was always just concerned about the interactions. I mainly just smoke weed. Try to stay off the opiates but it happens sometimes. Drink here and there that kind of thing but don't get drunk. Open to a trip once or twice a year but not any time soon. For the most part though, just a dabbler if at all. Too many former dependencies. I would imagine all dissos are out of the question?

 

[AlphaMethylPhenyl]

Parnate is supposed to be useful not just for depression, but for bipolar depression and for psychotic depression. That said, it's probably rarely a mono-therapy for these disorders. Usually a doctor will want one on a mood-stabilizer and/or an anti-psychotic in addition.

Yeah hallucinogens are generally a non-no for those with bipolar/psychosis.

 

[jammin83]

Thanks for the info Hochi. Probably won't ever try it but MAOIs are the only thing I haven't really tried. No mood stabilizer that is not an AP has ever really done much for me.

I react fine to psychs for the most part, not something I'm inexperienced with. LSD can cause a little mania or depression sometimes but easily handled, I have no shortage of APs at my disposal if things go south. Appreciate the concern though.

 

[paranoid android]

Not very good for bipolar depression you think? Or just because of the mania issue? Can't really take APs anymore after I get through this withdrawal. Went bad on me. Never really responded well to many mood stabilizers besides zyprexa. Stuff worked great when it did, but has totally fucked me off getting off of it. I've heard good things about MAOIs but was always just concerned about the interactions. I mainly just smoke weed. Try to stay off the opiates but it happens sometimes. Drink here and there that kind of thing but don't get drunk. Open to a trip once or twice a year but not any time soon. For the most part though, just a dabbler if at all. Too many former dependencies. I would imagine all dissos are out of the question?

I can't remember the exact combo but i think there was a pill that had Tranylcypromine aka Parnate along with Perphenazine which is a old typical mid-strong potency anti-psychotic. The Tranylcypromine helped the depression while the Perphenazine offset the stimulating effects of the Tranylcypromine and of course helped any mania or psychotic symptoms. Id imagine taking a newer fast acting anti-psychotic such as Zyprexa would help alot too although i would take many typical anti-psychotics over some atypicals because i find Risperidone to be awful for causing that zombie effect. Quetiapine could also be used though id say going with a true mood stabilizer like Lamotrigine or Lithium and a anti-psychotic as a add on if needed would be better. It's not that Parnate is much if any worse then say Zoloft, Prozac or worse yet Effexor but it produces a almost sort of non manic spurt of extra energy and feeling good in people that don't have Bipolar and aren't experiencing mania. But some doctors can misinterpret it for mania. Wellbutrin also can cause a sort of initial stimulant effect separate from it's anti-depressant effect and this is essentially what Tranylcypromine can often do as well.

Parnate is used to treat Bipolar depression but as was pointed out above it's not a monotherapy for it by any means. With Bipolar disorder you never give out anti-depressants by themselves anyway as they do absolutely nothing for the mania and often make untreated mania far worse and induce rapid cycling. Even the less risky ones for Bipolar such as Wellbutrin can do this.

Drinking is a no no on MAOI's but usual Opiates such as Codeine, Hydrocodone, Oxycodone, Morphine, Hydromorphone, etc should be safe but definitely stay away from any of the odd ones that affect other receptors and have toxic metabolites such as (Dextro)propoxyphene aka Darvon aka Darvocet, Tramadol, Tapentadol, Demerol and probably a few i am forgetting. However MAOI's can cause opiates to feel stronger so you would definetely have to wach that combo. Cannabis is okay but LSd and other tryptamines would be dodgy. No doubt you could end up making the trip much stronger and god knows what. They use a natural MAOI in Ayahuasca called Harmaline (a reversible inhibitor of MAO-A to make DMT active orally and that very rarely ever results in bad things happening.