Vicodin Tolerance

[Acerbee]

I recently got several vicodin (5mg/325mg acetaminophen) pills for recreational use four days ago. I've taken 2 pills a night every night for the last 4 nights. The first day I felt really euphoric and happy and the second day I was happy as well but with slightly reduced effects. The third day the effects were more reduced and now on the fourth day I can hardly feel any effects. I know my tolerance must have increased already.

I am curious to know how many days I would have to go without taking the vicodin to feel the euphoric effects again.

I also would like to know if vicodin tolerance would decrease the effects of percocets because they're both opiates or perhaps hydrocodone is different than oxycodone?

Thanks in advance

 

[SkagKush]

like a week in-between.......or you could dose more the next day..........

and yes there is a cross tolerance...

 

[Ksa]

Tolerance has a gaussian behaviour especially for opioids. This means that:

- waiting 5 days won't lower your tolerance a lot
- waiting 5 more days will start to lower it
- waiting 5 more days will lower it significantly more
- waiting 5 more days will lower it further little bit
- waiting 5 more days won't lower it much further

I would say after 25 days of abstinence you can expect something similar to your first time.

 

[Ksa]

It's the same when the tolerance kicks in. First 5 days of use not much develops, first 10 days, it starts to build up, etc.

 

[Pegasus]

Even one day off will help. You've just started taking them so this is especially true for you...

-> BDD

 

[CuriousSunflower]

Crappy tolerance on my part. Took 8 at a time a few years back, and after six months or more without....hardly does anything. Vicodin wires me for sound, and I'm about convinced it isn't comin back....sucks, outloud....

 

[IndustrialStrength]

Tolerance has a gaussian behaviour especially for opioids. This means that:

- waiting 5 days won't lower your tolerance a lot
- waiting 5 more days will start to lower it
- waiting 5 more days will lower it significantly more
- waiting 5 more days will lower it further little bit
- waiting 5 more days won't lower it much further

I would say after 25 days of abstinence you can expect something similar to your first time.

In the ops case this seems true.
In the case of a long term user this is less true.
After using for a year & a half I cold turkeyed & took a 2 month break.
Upon using opiates again my tolerance had not even lowered by 10%.
In fact using the same dosages I had used prior to the break I found that within 3 days of using I actually needed more than before I quit.
So don't expect to use opiates on a regular basis, quit & expect a large reduction in tolerance in any appreciable amount of time.

 

[Lucid Dream]

Don't forget, everyone that takes Vicodens start off taking 1,2, or 3 to get high, but anyone who has taken the drug longer than 6 months knows that you will NEVER feel the same off 3 Vicodens as you did when you started. So some tolerance with opiates is gained never to be lost.

 

[Ksa]

In the ops case this seems true.
In the case of a long term user this is less true.
After using for a year & a half I cold turkeyed & took a 2 month break.
Upon using opiates again my tolerance had not even lowered by 10%.
In fact using the same dosages I had used prior to the break I found that within 3 days of using I actually needed more than before I quit.
So don't expect to use opiates on a regular basis, quit & expect a large reduction in tolerance in any appreciable amount of time.

Take a 2 years break and try again. Never say never. 18 months is really long. Well, you're right though. It's a truth of life, good things aren't made to last. Happens with love, good tasting food, and any pleasure you may think of, not only with drugs. If it feels good, it won't last and the more you enjoy something, the faster it goes away.

 

[IndustrialStrength]

^^ Indeed.
I just wanted to clarify that with long term users, longer breaks are needed.
Like the 2 years you suggested for example.
So I agree with you on that.
Hell I agree on your other points as well.

 

[Ksa]

^^ Indeed.
I just wanted to clarify that with long term users, longer breaks are needed.
Like the 2 years you suggested for example.
So I agree with you on that.
Hell I agree on your other points as well.

It could be explained by the natural selection and evolution of life on Earth. Misery and pain is what drove life to evolve the way it did. It could be because a life form that's living in constant pleasure is unproductive because it wants to remain in that state forever and was therefore wiped out by other lifeforms who were more active and restless due to their permanent misery and discomfort.

Using oxycodone to wipe out millions of years of pain throughout evolution will not happen easily...the body will fight back to restore its origins at all cost.

May be it's a defense mechanism of some sort...a guy sitting in a corner fucked up on heroin is in danger because he is not productive in any way, he doesn't hunt...So the body responds by lowering the source of pleasure. I believe that tolerance to opioids can be fixed through genetical modification so in theory you could obtain human specimens that can get high and stay high all their life. But they wouldn't be much use to anyone right? And that's why they will never exist and no one will bother making them.

The state of pleasure is very close to death. If 7 billion people, right at this moment, were to be high on heroin for the rest of their days, it would mean extinction because nobody would do anything but sit somewhere and enjoy the high...The state of pleasure must never be a permanent state...only temporary.

Interesting ideas to discuss.

 

[amapola]

You can try mixing up your hydrocodone with some oxys or morphine based ops. Though all opiates are cross tolerant the more variation the better.