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unfounded claims from a friend

DeSpise

DeSpise

Bluelighter
Joined
Feb 23, 2003
Messages
570
ok id like to get your opinion on these things a druggie mate told me. a good mate who isnt retarded, i give his thoughs some weight at least :)

1)you build tolerance to certain brands of pills. ie. the same pill type. i can definately say i know what hes talking about, after caning those blue diamonds so much, they didnt do alot, but when i switched to something else they seemed alot better. im guessing its all about whats in the pills, but does that stretch to the actual isomers of the MDMA molecule, you get used to a certain ratio (ie the same batch)

2) he says that everyone has at least one drug they can take that will keep its good effects... ie he has consumed acid in the litres and still gets what hes after from it, totally jaded to pills and speed tho.

excuse me if i sound dumb or have asked a really common question, i am a bit etarded after all :)
 
1: well MDMA and MDA arent cross tolerant. So where you may be tolerant to MDMA pills a MDA pill will blow your mind (vice versa)

2: well that seems to be what happens from the years of seen of people take drugs. A lot of people have 'their drug' and LOOOVE its affects all the time compared to some/most other drugs they have used.

I'd write more but Im getting ready to leave for work. Hopefully I will have time to write more when I get there.
 
a) what waz said.

b) your friend has consumed acid in litres ? He must have been taking acid for a LONG LONG LONG LONG time. Acid doesnt seem to develop the same tolerances that the amphetamines do.
 
but does that stretch to the actual isomers of the MDMA molecule, you get used to a certain ratio (ie the same batch)
Click to expand...


In almost all MDMA seen, the ratio of Isomers (2 possible) is 50:50

This is because almost all MDXX is made from the ketone via reductive amination, and the further processes required to separate them are rarely done. It adds significant time/cost to the operation. A connoisseur may prepare his own with various ratios, but as for street gear.....

Tolerance quickly develops to most drugs, LSD being no exception. But the tolerance experienced from using LSD is different to that from MDMA.

Relevant endogenous brain chemicals are quicker to return to "normal" following LSD use, and while larger doses of LSD alter the affects of the drug to a certain point, respectively, larger or more frequent doses of MDMA tend to produce quite different -more amphetamine like - effects. These may feel nothing like the initial euphoria experienced from smaller less frequent doses of MDMA.
 
i wonder how much placebo plays in this?

remember when the red/yellow/brown 3s where out, after awhile everyone was like, "man im so over the 3s", but why? they were quality pills.

and im sure as soon as a new pill came out, with a similiar dosage of MDxA, everyone would be like, "have u had XYZ!?", "they are the bomb", "they are better then the 3s" etc..

and it builds up this excitement, about the latest pills...
 
^^^^
agree with placebo affect. its also exciting trying out a new pill.

but havin said that couldnt u say that tolerance builds on eating pills. but tolerance also builds on individual pills. just because not every pill of different brand contains exactly the same contents, be it, caffeine, mdxx, speed, psuedoehp.. so by consecutively taking say, blue dolphins, u build a tolerance up to its contents.

this is just my theory,.
just from experiecne with hitting the dolphins, 3's and diamonds.
 
keep in mind there are physical tolerances, as in your brain chemistry being physically altered in its ability to process the drug, and mental tolerances, in that, you may become more accustomed to the use of the drug and thus not feel as whacked out. This is not 'tolerance' as such, but simply you learning to control your own brain in that state better.

Think of the first time you got drunk...you probably didnt know wtf was going on and so made an arse of yourself...if you were to consume the same alcohol to bodyweight ratio today, you would know exactly whats going on, not feel as fucked and take precautions to not make a total boob outta yourself
 
^^^
Thats true. I actually have more fun on alcohol and weed now. The more i had them, the more fun i found them. Maybe because i was used to it, but its different for other drugs like opiates and E, you seem to build up a tolerance. I think the different MDMA, MDA, MDEA, Amphetamines ratio would probably be the reason for having different effects. Also may be a "breakthrough" point where you feel that much more fucked, which could come from an extra 5mg in a pill.

60mg of MDMA to 50mg of MDA (6:5), if you swapped the ratios to 50mg MDMA to 60mg MDA (5:6), the extra 10mg of MDA may be enough to push you over the edge to create a more fucked up state that your not used to.

Basically, 5 standard drinks may not be noticable but 6 may push you over into the "tipsy" range, making the experience somewhat different. I know different tolerances apply to alcohol but im sure you can see my point.
 
imnsho,

1. tolerance does develop to specific batches of MDxA pills, most likely due to the other active impurities in the particular batch.

2. definitely. for example, mj, caffeine, alcohol.
 
1. I think that if say 'x' pills have 100 mg of MDxA in them then the physicalogical effects will be the same (with some variation due to fitness, full/empty stomach etc) each time you take them. Any percieved tolerance is mearly in your head due to getting bored with the product. Now when you you take another pill with brand 'y' on it containing 100mg of MDxA your mental state is alot more excitable due to a "new" product. (note: your still ingesting 100 mg MDxA) I have seen this over and over again. Try puting aside a pill that you know is a killer but are getting sick of (ie 3's of yester year) until you have been eating another type of pill for a while. Then take it, see how you react.

2. I think that any drug of "choice" is simply that. It may be due to body makeup but I also think that some personalities tend to be atracted to particual drug/s. The effects on the bodies of these people are no different to anyone elses but they are able to deal with the bad effects better than some others or like the good effects more than others do
 
I always had a theory that the second batch is never as strong as the first batch, they suck u in with the strong ones and get a second sale with maybe only 5 - 10 mg less in each pill, but in mass quantity thats a shit load of E.
 
ive found that even when you bump the dose up of a same pill type it seems as though your 'used' to the felling somehow...
 
heh yeah i know :)
im talking about using the same pill 5 times over 2-3 months, and ramping up the dosage from 1.5 --> 3

not just eating a bunch of pills in one go
 
I tried to get an answer on old school ectasy thread but i was wondering because the mdma molecule has six different ways to synthesis it and there are different precursors as well, the end result of the mdma would all have there own unique character therefore having different effects on us humanoids wouldn't they? Its like alcohol it can be made different ways with different precursors the end result is we all get pissed in the end but each type always have different effects on us whether its a cheap vodka compared to a more expensive or a scotch compared to a bourbon. Calling Big Trancer maybe you could have your two cents
 
^^ It's worth remembering that no matter what the synthesis method is, the molecule is STILL MDMA. A MDMA molecule is a MDMA molecule no matter how you make it (except for stereoisomerism, but ok so then you've got d-MDMA and l-MDMA). If it wasn't, then it wouldn't be MDMA.

Chemistry is not like art -- there are no degrees and variations. Something is either MDMA or it isn't, end of story.

The reason different alcohols may affect you differently is due to impurities. Darker alcohols have more impurities, on the whole, and many of these contribute to the hangover.
 
phase_dancer said:
In almost all MDMA seen, the ratio of Isomers (2 possible) is 50:50

This is because almost all MDXX is made from the ketone via reductive amination, and the further processes required to separate them are rarely done. It adds significant time/cost to the operation. A connoisseur may prepare his own with various ratios, but as for street gear.....
Click to expand...


if you dont have a racemic mix of the isomers you wont get the "magic" feeling, even tho the S isomer is considered the stronger of the two. i dont think there is much of a point seperating the two isomers if it loses the magic :)

from http://www.ecstasy.org/books/e4x/e4x.ap.04/e4x.ap.04.05.html :

"In both rabbit and human studies, the more potent isomer of MDMA is the "S" form, similar to that of amphetamine and methamphetamine. The summed activity of the individual isomers did not satisfactorily reproduce the activity of the racemic mixture"

its also in pihkal (strangly enough its not under the MDMA entry) but i cant find the link right now.
 
VelocideX said:
^^ It's worth remembering that no matter what the synthesis method is, the molecule is STILL MDMA. A MDMA molecule is a MDMA molecule no matter how you make it (except for stereoisomerism, but ok so then you've got d-MDMA and l-MDMA). If it wasn't, then it wouldn't be MDMA.

Chemistry is not like art -- there are no degrees and variations. Something is either MDMA or it isn't, end of story.

The reason different alcohols may affect you differently is due to impurities. Darker alcohols have more impurities, on the whole, and many of these contribute to the hangover.
Click to expand...

So are saying there are no impurities in the production of md?
 
marklar_the_23rd Welcome to Bluelight.

Thanks for the reference, and while I agree on the accuracy, I'm tempted to ask you to define magic in relation to the "E" experience.

While a newcomer may find the 50:50 ratio as ideal, could it be that some "jaded" users may indeed respond more to an altered ratio of the isomers?


goodfellas; I believe VeloxideX is saying if someone intends to produce MDMA and has such an ability, then it is nothing to ensure a quality or pure product. The problem is that many small time producers are likely to try and capitalize on the extra profit; an extra gained from NOT purifying their product. Impurities have weight unfortunately :\
 
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