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Ultra-Rapid Metabolizer

brutus

brutus

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Several doctors have told me that I am an ultra-rapid metabolizer. I take 4 mg of Suboxone and 1 mg of Klonopin daily, but I notice that the effects wear off far more quickly than they should. Besides redosing, what would be the best way to slow down the metabolization of these drugs? I've tried GFJ and also Tagament, but there was little to no difference in the duration.

I've searched Bluelight and also Google, but the only thing I can find is information about health risks involving ultra-rapid metabolization and codeine. I figured ADD would give me appropriate answers.
 
Some people's livers' cytochrome P450 works faster than others.

If you really want to try metabolizing something fast, imagine IV
3,4-di-OAc-methamphetamine. MOM.
 
I would hope though that the resulting 3,4-dihydroxyamphetamine would be extremely rapidly excreted and wouldn't get to where it could do some serious damage.

its metabolism would be through plasma esterases with a half life of less than 10 minutes probably less than 5 minutes, so whether someone has super effective P450 is sort of irrelevant
 
Perhaps you are simply a very extensive metabolizer. Most people metabolize drugs quite extensively, some more than others. There are ways to test your metabolic rate, for example, testing to see how quickly the metabolite dextrophan forms after consuming dextromethorphan. If this was done, your physician would have no excuse to not prescribe more medication.

Maybe you should try the anti-depressant fluvoxamine (Luvox), as it is an inhibitor of CYP3A4 (enzyme responsible for the metabolization of buprenorphine). Or, perhaps you just need a dose increase.
 
An AD to slow down metabolism? That sounds a bit excessive. Why not just simple solutions like cimetadine instead of messing with psychoactive and potenitally addictive AD's.
 
Alright, thanks yall. I guess I will ask my doc for another dose to take during the afternoon. I just don't want to be seen as drug seeking, but I doubt he will think that since he knows I metabolize things very quickly.

Mods, feel free to close this. I figured taking another dose would be about the only thing I could do for this. Thanks again.
 
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