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  • BDD Moderators: Keif’ Richards

Triazolam tolerance and dependency

d3Xo-fan

Bluelighter
Joined
May 6, 2007
Messages
231
Location
In my head
Hi,

I'm still prescribed .25mg triazolam a day, but I take .5mg every other day instead. I feel no need to take it every day. In other words, I can easily lay off it. Please don't ask why I'm taking it at all then, because my question is this: recently I took a week off where I didn't take any triazolam at all, or any other benzo for that matter. No withdrawals occurred whatsoever. I have read that if you have a tolerance to a benzo it's very likely you are also, if only slightly, physically addicted to that substance. So since I didn't get into w/d's even though I abstained from triazolam for a whole week (and triaz has a very short halflife as you know), does this mean I also have no tolerance whatsoever?
 
From what I've read patients prescribed benzodiazepines don't normally build a huge tolerance. As I stated in another thread, therapeutic doses of benzo's ceiling out near the toxic doses. Also, I would like to break down a few definitions for you...

Physical Dependence: the state of requiring a drug for day-to-day functioning after prolonged use; stopping this medication will most likely lead to a withdrawal (there's no such thing as physical "addiction")

Tolerance: the need to take a larger dose of a certain drug to attain the same therapeutic doses as previously attained by a smaller dose

(Drug) Addiction: a disease or condition in which a person is psychologically dependent on a chemical; it is frequently characterized by intense drug cravings, most of/a lot of one's time being spent is comprised of drug seeking, loss of interest in things one used to find enjoyable, and abrupt secession may lead to psychological trauma

These words are not interchangeable. Tolerance is not dependence, which is not addiction. They each have their own meaning and should be used accordingly.
 
^^ You do realise the lethal dosage of benzo's is abnormally high right? the LD50 for alprazolam for example is like 15,000-20,000mg...

The therapeutic dose is muuuuuch lower. Considering you wont get prescribed much more than 12mg a day. I think 10mg is meant to be the maximum (here in australia) though i was on 12mg of alprazolam, 120mg diazepam and 2mg flunitrazepam daily.

Trust me... Tolerance is a massive bitch. When I first took any benzo's I was happy on 20mg diazepam... These days I need 20mg of alprazolam.
 
Okay, but if I'm not physically dependent on triazolam or any other benzo, does that mean I haven't developed the slightest of a tolerance?
 
I know someone that OD'ed and died from less than 30 4-bars. LDs do not reach up into grams.

Tolerance has nothing to do with dependence. Look at it like drinking alcohol. Just because it takes you more to get drunk, doesn't mean you're an alcoholic does it?

edit: after further reading I stand corrected. he didn't die from the xanax dosage per say. He died from the effects it had on him. Either way, saying something like 15gs of a substance that is rarely prescribed at more than 8mg per day should on a HR site.

And while the LD-50 was high in rats, you have to think that rats have a huge biological difference from humans. And I'm sure that the amount of stuff they've been exposed to has led them to evolve to be more resilient as far as chemical exposure goes.

Also on the Tolerance thing, I must have read an article that had false information. I do apologize for this.

Either way, the average human cannot ingest 15gs of xanax...
 
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Tolerance is one of the diagnostic criteria for dependence syndrome in the ICD-10. Tolerance doesn't mean you have a dependence, but there is a relationship between them.

Fatal overdose due to benzodiazepines alone is pretty rare.. not to say it never happens, but there are usually other substances involved. I'm really sorry to hear about the person you knew, Doug.
 
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They weren't super close. I smoked with him a few times. He went to high school with me. Really affected A LOT of the people that went there. Got some people to come clean off things. Now that I think about it, I think I remember hearing something about methadone as well at the funeral. But there was definitely xanax involved and a LOT of it.
 
I know someone that OD'ed and died from less than 30 4-bars. LDs do not reach up into grams.

Tolerance has nothing to do with dependence. Look at it like drinking alcohol. Just because it takes you more to get drunk, doesn't mean you're an alcoholic does it?

edit: after further reading I stand corrected. he didn't die from the xanax dosage per say. He died from the effects it had on him. Either way, saying something like 15gs of a substance that is rarely prescribed at more than 8mg per day should on a HR site.

And while the LD-50 was high in rats, you have to think that rats have a huge biological difference from humans. And I'm sure that the amount of stuff they've been exposed to has led them to evolve to be more resilient as far as chemical exposure goes.

Also on the Tolerance thing, I must have read an article that had false information. I do apologize for this.

Either way, the average human cannot ingest 15gs of xanax...

I'm just giving you what scientific data has said to be the LD50. I mean i've taken 100mg xanax and I woke up the next day. Having been prescribed 120mg diazepam, 12mg alprazolam and 2mg flunitrazepam daily I think I can state the facts of high dose benzodiazepine use. I didn't tell anyone to go and take 15g's. I said around there is the lethal dose of Alprazolam.

I've taken grams of valium and phenazepam and woken up on the other side. Sure lots of people die from high dose benzo's, but it isn't actually an overdose. I'm sorry to hear that your friend died due to how the xanax caused him to behave. All I was stating is that it's nigh on impossible to die on benzodiazepines alone, sure you do a lot of stupid shit, but you don't die unless mixing it with other CNS depressants.
 
I wasn't saying that the way he acted got him killed. I'm just saying that Xanax+SOMETHING got him killed and he probably wouldn't have died if he hadn't eaten all that xanax, but once you start taking them and you black out, you just keep taking them and taking them.

I came back and said that you were right, if you will check the post you quoted. And I wasn't saying you were telling people to go out and take 15gs of xanax. I was basically saying that you shouldn't be openly telling who fucking knows who is out there, that you can take a shit load of this drug and be fine, when most people who don't take it regularly, will start to black out on as little as 3-4mgs (2 bars).

Ya, they might not OD, but they might end up dropping 8 fuckin bars at once cause they think they're invincible or want to look like the hard ass, black out, and get themselves and possibly someone else hurt or killed. I was with someone that had to drop 4 1/2 bars at once when we got pulled over, and 15 minutes after that, he blacked out. Didn't actually come back until halfway through the next day. I've taken relatively small doses somewhere in the next town over from where I live, and then wake up in my driveway to my parents knocking on my car window, and I had apparently passed out mid-smoke cause there was a half-spent pipe in my hands. My point here is, this isn't good HR. I'm all about supplying the correct knowledge, and straying from propaganda, but there is no way in hell that it is alright to just post where any 12 or 13 year old could read "I've taken 100mg xanax and I woke up the next day," like it's no big deal.

But this isn't even what this thread was about, but you don't care about that obviously. This is what the thread was about:
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Q

Hi,

I'm still prescribed .25mg triazolam a day, but I take .5mg every other day instead. I feel no need to take it every day. In other words, I can easily lay off it. Please don't ask why I'm taking it at all then, because my question is this: recently I took a week off where I didn't take any triazolam at all, or any other benzo for that matter. No withdrawals occurred whatsoever. I have read that if you have a tolerance to a benzo it's very likely you are also, if only slightly, physically addicted to that substance. So since I didn't get into w/d's even though I abstained from triazolam for a whole week (and triaz has a very short halflife as you know), does this mean I also have no tolerance whatsoever?
-----------------------------------------------------------------------------------

And what I had stated first was just a little side note, that, apparently I had incorrect knowledge on, but I sure came and apologized for the wrong information and said that I stood corrected. But I'm pretty sure this answer would be something that would help him/her a bit better than us arguing over What's Its Fuck:
----------------------------------------------------------------------------------
A

Physical Dependence: the state of requiring a drug for day-to-day functioning after prolonged use; stopping this medication will most likely lead to a withdrawal (there's no such thing as physical "addiction")

Tolerance: the need to take a larger dose of a certain drug to attain the same therapeutic doses as previously attained by a smaller dose

(Drug) Addiction: a disease or condition in which a person is psychologically dependent on a chemical; it is frequently characterized by intense drug cravings, most of/a lot of one's time being spent is comprised of drug seeking, loss of interest in things one used to find enjoyable, and abrupt secession may lead to psychological trauma

These words are not interchangeable. Tolerance is not dependence, which is not addiction. They each have their own meaning and should be used accordingly.
------------------------------------------------------------
But like I said...You're right, I'm wrong. Congratulations, you have the bigger e-dick.
 
The benzo tolerance could increase in doses that you wouldn't believe. Tripman is right, if someone has built a tolerance, he could consume redicilous doses of benzo(etc. 50mg flunitrazepam). Off course d3X-o is not at this point, maybe your tolerance has raised just a litl..I think there's no reason to worry about..by the way, i haven't take triazolam for fuckin years, you remind me how good it is, fuckin shit..


MartinFn
 
Doug2113, thank you for getting people back on topic. I was actually a little frustrated some of you started talking about something completely different :D

MartinFn, I suspect you are right on. I think I have a small tolerance. It doesn't bother me that much as long as I'm not physically dependent though. But when you hear people get really stoned from 0.25 - 0.5mg triazolam and I can take 2mg and not feel it you get a little disappointed :( Maybe I just overestimated it. I always thought it would be better than flunitrazepam since it's stronger but I still find flunitrazepam to pack way more of a punch, whereas triazolam comes on smooth. Quick but smooth.

Thank you for your answers!!
 
If you are going to be Rxed a drug constantly for the rest of your life, tolerance and dependence aren't a big deal and these conditions are completely expected. It's when you start having the psychological addiction that it starts to become an issue. Your life revolves around getting the drug. It affects your performance in all aspects of life and controls each and every step you take. If you need to take a medication to help you have a better quality of life, the first of these doesn't really matter. It's just latter of the two that's an issue. Improvement in quality of life is why people are prescribed drugs anyway. Their risk:benefit ratio is low enough that it will improve their life as opposed to make it worse. But I'll get off my soapbox now. I hope everything works out for you.
 
^^Well, you speak so right, Doug. What can anybody say, after that? I just agree with you,that's the reason of a drug that somebody takes:to improve the quality of him/her life..the problem start when you start having psychological addiction..


MartinFn
 
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