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Treatment for sexual dysf. arising from methylphenidate use - bremelanotide?

Valium

Bluelighter
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Jan 22, 2005
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And phosphodiesterase-5 inhibitors, and apomorphine apparently also helps as a centrally acting agent, and it is thus a hypothesis waiting to explode into irrevocable truth...

These agents seem promising, from what I've read, as cent. acting preparations that are a tad more complex than vialis and the like in their mediation of n.trans. (at least the most important ones pertaining to sexual arousal) in order to 'normalize' the sexual arousal response in both men and women (but mostly men of course).

My buddy-boy has been anguishing and languishing away since he started his mpd treatment for ADHD because his sexual response is abnormal to the point of not being able to perform at the snap of a whip like most men of his age can, but most horribly, hardness of erection can barely be called that...it's more of a slightly erect yet visibly flaccid penis. And the woman he is with comes from some amazonian tribe where sex is mandatory 1 session t.i.d. and the like..on the clock - or else ..bad moods arise and nobody wants that.

The doctor's response to this was "i've never heard of this before" and suggested reducing the dose, or throwing in an anxiolytic, thinking it was anxiety that led to the erectile malfunction, but later it turned out that anxiolytics made erection literally impossible, even in microdoses of the strongest, as well as weakests benzos. When it became a headache for the doctor [god forbid he do research in his spare time], he said ''this is a very common problem, it happens to all my patients,.....just give it some time..it will go away. play some enigma and light scented candles and the penis will skyrocket'. you know what i mean.

Is it possible to augment the methylphenidate with something that will take away the sexual dysfunction, even if partially, and not inhibit the effect of the primary drug?
If in MDD, patients experiencing sexual dysfunction, for instance, are administered another AD with a "no sexual side effects profile" as an adjunct to their treatment....can't the same be done with methylphenidate and amphetamines? It seems to me, it's not quite clear how the adjunct AD with the good sex profile suddenly makes things all better [well it's somewhat clear but not completely, as always is the case], so might it not be possible that the same can be used with they symp.amines either by augmenting with another symp amine with a good sex reputation or an AD?
It seems as if it might 'sort of work', however, I've been unable to find this exact topic anywhere, published and studied thoroughly - probably because flaccid erection is not typically associated with the 'uppers' that are used at the clubs to facilitate spread of STI....

Does anyone know anything about this? Maybe some older material anyone can point me to? PubMed wasn't nice to me in this particular instance.
 
Try viagra and/or pramipexole...not sure if there would be any dangerous interaction with the methylphenidate though so talk to the doctor about it first and start with low doses!
 
i would offer a non drug solution for the time being :

a dildo , or even a man-strap-on could become part of the play.

as for the drug (non)solution :

my boy had bad reactions to PT-141 ,
seems that women react better to this substance.

cialis worked wonders for him.

your ex.
 
only if you're looking for serious blood pressure problems.

Could you elucidate? In your view are sometime (or every day, in the OP's case) doses of PDE-5 inhibitors contraindicated with therapeutic doses of a vasoconstricting psychostimulant? What if the vasoconstriction from the therapeutic dose is not significant?
 
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bremelanotide isn't a PDE-5 inhibitor. They lower blood pressure (or at least the marketed drugs do). Bremelanotide is very, very different.

It was pulled from development because of it raising blood pressure significantly.
 
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