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  • BDD Moderators: Keif’ Richards

Misc Trazadone vs. Mirtazapine

E

evo4ever

Bluelighter
Joined
Jun 14, 2016
Messages
1,398
Location
UK
Hello all.

Currently I'm on Mirtazapine for major depressive disorder and recently I self harmed by cutting my self with a knife. It's the worst episode of self harm I've been through, it was a very deep laceration (to the bone) to my left arm requiring 10 stitches, I was lucky I missed any nerves or arteries! 😔

My mental health team are reviewing my medication and I was wondering whether Mirtazapine is similar to Trazadone in terms of sedation?

Cheers guys.
 
Totally depends on your own neurochemistry, friend.

Sorry to hear about your troubles. Personally I find low dose Mirtazapine more sedating the trazadone. Both make you feel like a zombie to start but become bearable as time goes on.
 
Jeez, sorry to hear that happened, and I wish you the best with recovery. Try to keep your head up and stay positive, feel free to reach out if you need someone to vent to.

My last major episode 3 years ago, I cut myself pretty damn bad. I only had 6 stitches I think. I did actually sever an artery. It was really damn bad, and I probably would have died if I was alone when it happened. I've got a gnarly scar from it and will forever. I try to look at it as a reminder of the difficult things I've been able to make it through, so I remember that I don't have to give up when things get difficult.

To your question though, it definitely does depend on your personal reaction to it as stated above ^^

I've taken both of them at various times, and in my experience, I think they are somewhat comparably sedating in the short term, but Mirtazapine seems to have more lingering sedation, like the next day and stuff. Mirtazapine is heavy on the histamine receptors, I'm not as familiar with trazodones pharmacology.

Overall I've had much better results with Mirtazapine, but I have never taken trazodone at antidepressant dosages over a long period. Mirtazapine has worked great for me as an antidepressant and I still take 7.5 - 15mg daily. The side effects from trazodone are kind of shitty and annoying honestly. So much dry mouth, it totally kills it's value for me just from that, and the risk of priapism (neverending erection) is kind of freaky.

Are you in therapy or do you have any other social support? Definitely something to consider.

Stay safe and take care of yourself 💓 🙏
 
Thanks for the replies guys. I've got pretty bad insomnia as well which also has a negative effect on my mood. Do you think it will be a good idea to get a few benzos (Temazepam) off my psychiatrist who's dealing with my med review? My psych team did bring up sleep meds with me when they visited me a few days ago and they recommended zopiclone and promethazine.
 
Yeah, theses issues tend to go hand in hand. I think getting a good night's sleep helps you cope with anything a lot better.

So if you can't sleep then I'd say try some sedatives to get you back on track. But don't end up relying on them. Personally, promethazine is pretty shit and the dose I had to take to sleep ends up causing nasty hangovers. Temazepam is good but I do find it kinda weak. I do have a tolerance to all these drugs and a couple decades heavy drinking doesn't help. Id say zopiclone is decent and doesn't cause as much hangover but prolonged use will exacerbate daytime anxiety. You'll be fine for a couple weeks though. And if you haven't really used it before it should work out good. The key is to use these meds to cultivate a good routine and stick to it religiously to stop insomnia returning.

Absolutely agree with everything @deficiT says above. Meds are just symptomatic treatment and at some point you have to deal with the root cause. So consider some kind of talking therapy or counseling if things are that bad.

Feel free to PM if you want to discuss further.

But, please do not keep self harming. You deserve better. Please remember that.

BB
 
BadBoy377 said:
Yeah, theses issues tend to go hand in hand. I think getting a good night's sleep helps you cope with anything a lot better.

So if you can't sleep then I'd say try some sedatives to get you back on track. But don't end up relying on them. Personally, promethazine is pretty shit and the dose I had to take to sleep ends up causing nasty hangovers. Temazepam is good but I do find it kinda weak. I do have a tolerance to all these drugs and a couple decades heavy drinking doesn't help. Id say zopiclone is decent and doesn't cause as much hangover but prolonged use will exacerbate daytime anxiety. You'll be fine for a couple weeks though. And if you haven't really used it before it should work out good. The key is to use these meds to cultivate a good routine and stick to it religiously to stop insomnia returning.

Absolutely agree with everything @deficiT says above. Meds are just symptomatic treatment and at some point you have to deal with the root cause. So consider some kind of talking therapy or counseling if things are that bad.

Feel free to PM if you want to discuss further.

But, please do not keep self harming. You deserve better. Please remember that.

BB
Click to expand...

I've been through a lifetime of rape, abuse, bullying, and trauma. My problems are very complex and deep seated, I'm scared it's all set in stone because I've tried literally everything and nothing has worked. The way I've been treated from a very young age up until now has given me multiple personality disorders :(

I'll list all the mental health disorders I've been diagnosed with:

Major Depressive Disorder
Generalized Anxiety Disorder
Borderline Personality Disorder
Avoidant Personality Disorder
Post-Traumatic Stress Disorder
Severe Insomnia (made worse by nightmares, flash backs, and bed soiling)
 
Last edited:
That's horrendous. I'm really sorry you've been so badly treated.

I really hope you can find a positive way forward. If there's anything I can do to help just reach out.

Stay strong.

BB
 
evo4ever said:
I've been through a lifetime of rape, abuse, bullying, and trauma. My problems are very complex and deep seated, I'm scared it's all set in stone because I've tried literally everything and nothing has worked. The way I've been treated from a very young age up until now has given me multiple personality disorders :(

I'll list all the mental health disorders I've been diagnosed with:

Major Depressive Disorder
Generalized Anxiety Disorder
Borderline Personality Disorder
Avoidant Personality Disorder
Post-Traumatic Stress Disorder
Severe Insomnia (made worse by nightmares, flash backs, and bed soiling)
Click to expand...
I'm really sorry you experienced that. I can empathize on some level, I also deal with severe BPD and PTSD symptoms from abuse, trauma, and neglect I experienced from a young age.

It's difficult I know, but try not to despair or catastrophize. You can't undo what has been done, but you absolutely can learn to cope with your problems. Recovery, and living a better life is 100% possible, sometimes it's just hard to see. Processing those kinds of traumas is a lengthy and radical process. Try to be patient with yourself and give yourself some grace for whatever mental health problems you are experiencing. You didn't choose to be hurt, and feeling bad is a normal reaction to extensive pain. All you can do is move forward and try to be a better person today than you were yesterday.

One thing that has helped with my bpd symptoms, is I try to be the person I felt I've needed in my own life for others in the world. If that makes sense. All of the emotions and resentments that accompany BPD can blossom into a lot of toxic feelings and behaviors if you don't actively try to work through them.

At the end of the day though, I do hope you don't feel like any of your issues are set in stone. Mental health diagnoses are an important tool for understanding yourself and the things you're struggling with, but they aren't all encompassing. On an individual and social level, you are so much more than any diagnosis. I've actually begun to appreciate some of my own neuroses, as I feel they help me see and interact with the world in a way that most are either unable or unwilling to.

Just keep working towards the light, one day at a time, and you will get there, don't give up on yourself before you have the chance to shine 🙏 ❤️
 
deficiT said:
I'm really sorry you experienced that. I can empathize on some level, I also deal with severe BPD and PTSD symptoms from abuse, trauma, and neglect I experienced from a young age.

It's difficult I know, but try not to despair or catastrophize. You can't undo what has been done, but you absolutely can learn to cope with your problems. Recovery, and living a better life is 100% possible, sometimes it's just hard to see. Processing those kinds of traumas is a lengthy and radical process. Try to be patient with yourself and give yourself some grace for whatever mental health problems you are experiencing. You didn't choose to be hurt, and feeling bad is a normal reaction to extensive pain. All you can do is move forward and try to be a better person today than you were yesterday.

One thing that has helped with my bpd symptoms, is I try to be the person I felt I've needed in my own life for others in the world. If that makes sense. All of the emotions and resentments that accompany BPD can blossom into a lot of toxic feelings and behaviors if you don't actively try to work through them.

At the end of the day though, I do hope you don't feel like any of your issues are set in stone. Mental health diagnoses are an important tool for understanding yourself and the things you're struggling with, but they aren't all encompassing. On an individual and social level, you are so much more than any diagnosis. I've actually begun to appreciate some of my own neuroses, as I feel they help me see and interact with the world in a way that most are either unable or unwilling to.

Just keep working towards the light, one day at a time, and you will get there, don't give up on yourself before you have the chance to shine 🙏 ❤️
Click to expand...

Thanks for reassurance. For the first time I'm working with a Clinical Psychologist amongst other medical professionals atm so hopefully things might start getting better, but I've been told it won't happen over night, it's going to be a long process.
 
I also have had major depressive disorder. Got diagnosed at 16 I'm in my 30s. I've tried every anti depressants out there none of it works. Of course they don't like to give us any of the good drugs that work for sleep, I'm a huge insomniac and it's part of why I turned to drugs.

I've found mirtazipine does kinda work for sleep, but trazadone is absolute trash just stay away from that. Gives you terrible nightmares and sleep.. for me it did anyways. But yea mirtazipine aka remeron works okay for sleep for an anti depressant
 
Chaos21 said:
I also have had major depressive disorder. Got diagnosed at 16 I'm in my 30s. I've tried every anti depressants out there none of it works. Of course they don't like to give us any of the good drugs that work for sleep, I'm a huge insomniac and it's part of why I turned to drugs.

I've found mirtazipine does kinda work for sleep, but trazadone is absolute trash just stay away from that. Gives you terrible nightmares and sleep.. for me it did anyways. But yea mirtazipine aka remeron works okay for sleep for an anti depressant
Click to expand...
Yeah it's one of the marginally better things in selection of pretty shit meds imho.

Have you tried any of the melatonin pathway antidepressants? I've heard of people who've done everything else have some success with them.
 
BadBoy377 said:
Yeah it's one of the marginally better things in selection of pretty shit meds imho.

Have you tried any of the melatonin pathway antidepressants? I've heard of people who've done everything else have some success with them.
Click to expand...

No I've never tried Melatonin. Can I get it without a prescription?
 
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