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  • BDD Moderators: Keif’ Richards | negrogesic

Tramadol

A

adderallmonsta

Bluelighter
Joined
May 3, 2012
Messages
88
I have run out of other stuff and i have been using Tramadol and i take a lot and smoke a but and im pretty fucked up. Has anyone here smoked one I want to try it.
 
Careful, those will severely lower your seizure threshold. Not a good drug for an opiate user to abuse. I would advise you not to try smoking it
 
Smoking pills is never a great idea due to the fillers in the pill that can be fairly toxic when burned and inhaled.

Tramadol is best used as prescribed for the reasons in the aforementioned post above.

Be safe!
 
Haha I'm just seeing...Well Hebb22 you sound like you know a lot about opiods can i like instant message you on skype or something like that or oovoo i need to ask questions
 
Virtually all opioids can be smoked, or vaporized (though, the bioavailabilities are typically lower than their oral bioavailabilities)

Should you smoke or vaporize a pill? No, that's really just stupid... You think tabacco is unhealthy? Well how would you feel about particles of silica and all kinds of other shit in your lungs... not to mention smoking is a chemical reaction, so who knows what other shit is produced during the combustion of the pill

If you somehow extracted the opioid or opiate from the pill, that is a different story... in which case one could just go through trial and error and figure out how to effectively vaporize the powder out of something like an oil burner (meth pipe) or off tin foil (not recommended, not healthy)

But I doubt you're going to successfully extract pure opioids from the pills...

So, basically... BE HAPPY WITH THE ORAL ROUTE OF ADMINISTRATION
 
People use to smoke the old formulated OC's but ive never heard of anyone smoking Tramadol. Im one of the unlucky people that cant get much out of Tramadol except for zoning to where I feel like im on speed.......weird.
 
PLEASE, please don't smoke pills. This causes irreversible and permanent damage to your lungs. Unlike with cig or pot smoke, your lungs do not have the ability to remove the bindings in the pills. It can and will cause dangerous complications.

Worst of all, you will not even get anything extra out of smoking any opiate pill, except for a faster onset and shorter duration. Tramadol is around 90% orally bio-available I believe. Just stick to swallowing or plugging it.
 
^ yeah indeed.

as others said, smoking (or more accurately vaping) opioid-containing pills is not a good plan. horrible for your lungs, and often really wasteful too.

tramadol has SNRI properties as well as being an opioid, which can make withdrawal even more vicious. you need to be careful about your dose too - no more than 400mg/24 hours as it lowers the seizure threshold. be careful not to mix it with any other CNS depressants (alcohol, benzos etc) or any other drugs which can also lower the seizure threshold. people have seized on less than 400mgs; it is a very real risk. take it steady :)
 
Smoking, snorting, IV'ing, sublingualing, and plugging tramadol are all inefficient if you want to feel the opioid effects, since tram has to make it through first-pass metabolism (oral route) to be converted in to O-Des by the liver.
 
^^ Tramadol will be converted to o-desmethyltramadol whatever the ROA. You're right that oral ingestion results in first-pass metabolism, whereby following absorption the drug is transported to the liver via the portal vein and is metabolised before it hits the brain/rest of body - but whatever ROA you use, once it is in the bloodstream it is going to make it's way through the liver and be metabolised into o-dt.

That's not to say it's a good idea to consume it via a different ROA of course - smoking is very bad for your lungs, insufflated has a really low bioavailability and IVing pills is even more dangerous than regular IVing - but plugging would work and has a slightly higher bioavailability than oral (see bioavailability thread).
 
boundforglorywt said:
i've tried smoking one in the past and it was absolutely horrible, no high from it either. all around terrible experience
Click to expand...

I never heard of anyone smoking it until today...
but I would've just assumed nothing would come of it, anyway..

off topic: likes your screen name

:) token
 
effie said:
^^ Tramadol will be converted to o-desmethyltramadol whatever the ROA. You're right that oral ingestion results in first-pass metabolism, whereby following absorption the drug is transported to the liver via the portal vein and is metabolised before it hits the brain/rest of body - but whatever ROA you use, once it is in the bloodstream it is going to make it's way through the liver and be metabolised into o-dt.

That's not to say it's a good idea to consume it via a different ROA of course - smoking is very bad for your lungs, insufflated has a really low bioavailability and IVing pills is even more dangerous than regular IVing - but plugging would work and has a slightly higher bioavailability than oral (see bioavailability thread).
Click to expand...

ok. you're right. I'm wrong. taken care of. thanks.
~token
 
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^ You were absolutely correct about first pass metabolism though, and that oral probably is the best ROA :) plugging doesn't really have any significant advantages and is a lot more hassle.

edit: and am doubting myself now, is 5am and not had any sleep haha..
 
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effie said:
^ You were absolutely correct about first pass metabolism though, and that oral probably is the best ROA :) plugging doesn't really have any significant advantages and is a lot more hassle.

edit: and am doubting myself now, is 5am and not had any sleep haha..
Click to expand...


Thanks..and sleep!
:)
 
Wow, I didn't know that, effie. Yeah, I always wondered why IV tramadol was used in hospitals for pain, I used to think they were just getting people speedy by shooting them up with tram so they wouldn't notice pain with quickly increased 5-HT and NE, but that's so unconventional, lol

So if I am right about first pass metabolism, why was I right if it all goes to the liver anyways, regardless of ROA?

Also, would I be wrong in guessing that any ROA quicker than oral tends to release 5-HT more quickly, and tends to increase the risk of seizures over the oral route?
 
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