I took Tramadol 225 mg with naproxen 500mg script, I was ok.
Just a very gentle reminder my good friend: January 2021 is only a hop, skip, and a jump from here! Just thought I'd remind you...
+1 for choosing a different painkiller. I've been given tramadol in the past for really severe pain and found it to be completely useless. YMMV applies though.Yeah I think it's okay. Tramadol at these doses has no risk of respiratory depression. Also Z drugs don't know if they will have the same danger as benzos.
Yeah it's just tolerance my friend, If you continue at thid rate, in a couple of months you will be taking almost 1 gram. Are you in a lot of pain or just for recreational use? Perhaps you should choose another painkiller with a safer therapeutic range. Tapentadol is excellent. I never get tired of advertasing this opioid jahaha.
Regarding seizures, if you don't have a family history of epilepsy, there should be no problem. I suppose you're staggering your doses, right? Because taking 400 mg. in a single shot is much more dangerous than doing it in several shots (aka staggering doses). I think if you gradually increase the dose slowly, there should be no problem, since it's not like 400 mg either. = seizure right away. Only the odds are increasing a little bit. I, who irresponsibly took 1700 mg in a night without any benzos or anticonvulsant, possibly had 1/3 chances of having seizure but I didn't have one. Lucky or my seizure threeshold threeshold it's naturaly high.
Thank you my friend, I never heard if tapentadol, yes it’s for pain, but I also like the mellowing affect, I usually only use it on the weekend when I don’t have to work, and bear the pain, but being this was a holiday weekend I had a couple more days off.Yeah I think it's okay. Tramadol at these doses has no risk of respiratory depression. Also Z drugs don't know if they will have the same danger as benzos.
Yeah it's just tolerance my friend, If you continue at thid rate, in a couple of months you will be taking almost 1 gram. Are you in a lot of pain or just for recreational use? Perhaps you should choose another painkiller with a safer therapeutic range. Tapentadol is excellent. I never get tired of advertasing this opioid jahaha.
Regarding seizures, if you don't have a family history of epilepsy, there should be no problem. I suppose you're staggering your doses, right? Because taking 400 mg. in a single shot is much more dangerous than doing it in several shots (aka staggering doses). I think if you gradually increase the dose slowly, there should be no problem, since it's not like 400 mg either. = seizure right away. Only the odds are increasing a little bit. I, who irresponsibly took 1700 mg in a night without any benzos or anticonvulsant, possibly had 1/3 chances of having seizure but I didn't have one. Lucky or my seizure threeshold threeshold it's naturaly high.
Interesting read. .
Apparently liver failure could happen after an acute overdose of tramadol, but this site says generally normal therapeutic doses aren't very harmful to the liver.
This was last updated in April 2020.
"In some situations, acute liver failure after tramadol overdose may be related to acetaminophen taken separately or in combination with tramadol. Clinically apparent idiosyncratic liver injury with recommended doses of tramadol has not been reported."
"The minor enzyme elevations that occur with tramadol use are usually mild, asymptomatic and self-limited, resolving even with continuation of therapy. Cases of acute liver failure due to tramadol overdose require intensive medical management and can be fatal. In acute overdoses, there may be interaction with other agents capable of causing liver injury (particularly acetaminophen)."
It sounds like a lot of people who may have had liver issues after using tramadol may have been using incredibly high doses and taking drugs that interacted with the liver as well.
I swear I read awhile back ago too that tramadol was a recommended opioid for people with renal failure or kidney problems, since it is not metabolized in the kidneys. I could be wrong however though, it's been a long time.
I will have to do some more digging on this topic. As for my anecdotal report, I survived 400-600mg doses for quite a long time, without any damage that i'm aware of. I do recall some times looking like my eyes were jaundice after taking a hefty dose of tramadol. So I would not be surprised honestly if it did have some impact on the liver, but probably nothing compared to some one who drinks every day. Which I also use to do a lot of.
I use to take high dose tramadol, smoke lots of meth, do dirty street heroin, drink vodka and drink dxm. I'm surprised my organs still function at all.
Thank you for your concern my friend I don’t want to get addicted so I’m going to stop,