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tramadol as an anti-deppressant?

in your other thread you mentioned tianeptine. have you used it in conjunction with tramadol? tramadol on its own is working very well for me, and i just want to bring it to full potential. thx for the reply, and sry to hear of your troubles.
(20 posts to get BL status btw)
 
I imagine tianeptine + tramadol is a potentially very dangerous combo (Serotonin Syndrome risk).

Although I agree, these two are the only serotonergic antidepressants that worked for me.
 
I have said this in another thread, but I will say it again.

Tramadol + Phenibut is the best mix you can do.

Do not stray to far from GABAergic substances when mixing with tramadol because of the risk of seizure.

I am scripted Tramadol SR 300mg/day for knee pain. I have been on this dose for over a year. No need to increase the dose. It has worked for both pain and depression.

If it was not for Tramadol, I would be on Buprenorphine, which I am sure is just as good ;)
 
well, I Must say I have a long experience with TRamadol, cause I take it on a regular schedule for my neuropathic pain syndrome almost ever day since 2 years. I tried alot of fucking shit before TRam (like carbamazepine, gabapentine, Lyrica) , but trama worked best. The fact is tolerance does build up for tramadol (the max. dose I took daily was about 1000 mg daily , 10 100 mg retard pills, without seizures). I wonder if someone knows anything about some substance that rebuilds senstivity to tramadol , at least to the MU effect.....maybe some muscle relaxant like carisoprodol? or glutethimide? None of these are available in my country (I live in romania, U know), nor in the EU as long as I know...and believe me I do ...Im a medical professional....RO is the only EU country that lacks dextropropoxyphene....hehe

what about the metalloprotease endorphinase inhibitor class?
 
I have taken Tramadol when on a SSRI (Escitalopram),a SNRI (Cymbalta) with no detrimental effect,ditto with Trazodone,the latter though reduced Tramadols activity.I don't think Tramadol and AD's are per se contra-indicated (Bupropion and the older AD's being the exception).
 
Not only is Tramadol w/d a reality, but I think it has more devistating psychological effects then your typical opiod (hydrocodone, oxycodone) because of the seretonin-affected dispersal of the drug in the brain.

So responding to the idiotic (and offensive) notion that withdrawal from tramadol (and other opiods):

"i've never noticed any withdrawal symptoms from tramadol though i've been consuming it for 6 years irregularly and for 1 year regularly now. therefore, i think that each claim of withdrawal is pure imagination, maybe some sort of anti-placebo or depending on one's current psychological condition."

WOW
 
i spoke too soon about the tolerance to anti-depressant effects. into the 5th week now and i've had to increase the dose :( lost that energy/motivational feeling.

tried phenibut but was not impressed. i guess its a good compliment to the tramadol if it reduces the seizure risk, but it's pretty draining / laggy ... not really complimentary to the energizing buzz of the tramadol.
 
^ the little generic 50mg tabs ... i assume they're IR? just simple pressed pills no coating and not a complex gel or anything.

the phenibut is just bulk powder in caps. whats a good dose for it, like 1g?
 
after spending a little time thinking about this, I'm here to report my own draw toward tramadol has been based on delusions. I thought I could find a pill that would make me happy with no consequences. well, I need not take tramadol to realize that this will not happen. Tramadol might mask/soothe me on days that I feel a little 'down', but I'd rather work on my head by other means (exercise, meditation, just living a good life) than take a drug for it.

I'm not trying to project my trip onto anybody else, just throwing it out there for food for ya'll.
 
I just (i.e. 30 minutes ago) dosed my first real Tramadol (prior was one bout with extended release tabs that didn't do anything) . It was something I'd never really been interested in, seemed like the poor man's opiate.

I combined it with some codeine, to round off the high (I love codeine), and diazepam, to reduce the propensity of seizures,

300mg, and wow. Not only do I feel quite lovely; warm, comfy, cosy, etc (I could probably lie down and nod out right now), I find the mental effects amazing.

I don't really suffer from depression (no more than your average joe with the problems life throws at us), but more importantly, I feel confident and supremely just, well, on top of the world! Internal elation.

I was just on the phone to someone very important, business-related, and I absolutely dominated the phone call. It was easy, the words came straight to me, and I was charming, smooth tongued and polite (even moreso than usual ;) )

So, I can imagine that for those who have depression, it would work wonders. For a week. Until you build up tolerance, lose the anti-depressant qualities, and end up having a seizure because you've upped your dose way too high to counter the aforementioned effects.
 
IlostaMadge said:
I have a friend that self medicates on tramadol, he takes 200mg a day, and finds it a very good anti depressant.
I think he uses it for mood regulation (he claims that it flattens the emotional lows and highs), apparently he still gets a "high" from it if he takes 150mg+ in one go.
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does this friend have bipolar? i have bipolar and a mild case of boderline personality(common co-morbid with bipolar). i works like nothing else, 150mg in the morning then thats it for the day. i still get a mild high, though i would not call it a high (its more functional calmness). you still get depressed on it and manic but its easier to control those states and the paranoia is not incapacitating, therefore you can function at work far better and in the long term then get a proper career:)
 
morphiquet said:
i think the key for getting (mental) health benefits here is not a constant level of active tramadol in the blood like it is thought for common antidepressants for them to be effective, but rather to get this kick reliably each morning.
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this is exactly my experience with it if the dose in the blood was constant you would evelop a tolerance making it ineffective, having one morning dose means you are not totally under its influence all the time yet it seems to retain the good mood all day but the next morning feel slightly cold then trams and normal again
 
Tone303 said:
can you believe this??? someone named colors private messaged me a question about tramadol as an antidepressant, and i cant send a message back to him or her because it says i cant PM a staff until i have "bluelighter status"

because of this i have to embarrass myself and post my reply publically!



all SSRIs are incompatible with Tramadol. All antidepressants are incompatible with it, even if its not an SSRI, for instance wellbutrion lowers the seizure threshold just like tramadol does so they cant be taken together

I have to tell you that Tramadol is ending up as a dead end for me. i am an extremely severe depressive. The tramadol helped me to go out and meet people, but no one would have anything to do with me. im not even able to date anyone because of a 100% rejection rate.

so, in terms of your combo with tramadol question, its possible that tramadol could work in combo with Love or having friends or being able to do something you love, but it sure doesnt work if you are a loner.

Thats the very novel and unexpected answer i have for you.

I believe in using anything you can that will relieve depression. any other people on the board who dont believe this, is simply because they dont experience depression, so they arent desperate for relief.

myspace.com/tone303
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you MAY never get depression under control IF you dont have a social network, make an effort to gain one, develop interests in life you can do on your own, eat healthily and get as much excercise as possible. depression requires mental effort on your part to help deal with the black and white thinking that makes your behaviour come across to other's as antisocial.

i have depression and mania and find depression is very self absorbed and antisocial and mania is very socially engaging but lacks morals and awareness of reality.
 
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