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  • BDD Moderators: Keif’ Richards

Opioids Tramadol after pregabalin.

zenzan

Greenlighter
Joined
Jul 16, 2019
Messages
24
Hi, So i stopped taking tramadol few weeks ago when 150mg wouldn't cause me enough of the amazing effects. Started pregabalin 150mg instead (with last night being 300mg, it was fine, not a great experience as effects were not too strong as i imagined). After 3 weeks of taking pregabalin, i kinda wanna take tramadol tonight. However, in the interest of harm reduction, would like some advice:

Since i know pregabalin stoppage can cause seizures and tramadol itself causes them or reduce seizure threshold. Would 150mg be okay tonight?, or should i rather stick to 112.5mg tramadol? and ofcourse no pregabalin since i would not wanna have any excess CNS depression. (also, out of pregabalin, will buy more tommorow).


PS: Ive already taken 75mg of tramadol. Based on the answers, ill take 37.5mg more or not later.


Hope you guys stay safe.
 
You'll be fine.

Even 300mg pregabalin plus 150mg would be safe enough since you have a tolerance. Some people combine opiates with pregabalin for potentiating it. I wouldn't encourage regular poly drug use. Or even at all.

But respect for going out n asking for safety's sake.

Have a good evening,

BB
 
Well im not looking to mix at all, Mixing would be safer in terms of seizure since pregablin stops them and tramadol may cause them. Im just hoping to not take pregabalin at all today and rather just take tramadol. Considering not taking pregabalin today makes my seizure risk higher, and taking tramadol also raises the risk. Or maybe im over thinking? Hence advice needed lol.
 
Well im not looking to mix at all, Mixing would be safer in terms of seizure since pregablin stops them and tramadol may cause them. Im just hoping to not take pregabalin at all today and rather just take tramadol. Considering not taking pregabalin today makes my seizure risk higher, and taking tramadol also raises the risk. Or maybe im over thinking? Hence advice needed lol.
No one knows since everyone responds to drugs different and each individuals seizure threshold is different.

All anyone can tell you is yes you're taking a risk. If you're worried about it wait a few days for everything to return to baseline before taking the tramadol. You could also take a small does of pregabalin then take the tramadol after. Or cut the tramadol does down so it isn't at the upper limit of inducing seizures in most users.

Too much pregabalin can caused seizures too.

This is also true as I've discovered more than once over the years. Typically, when it does happen you're already so out of it that you won't be aware of the seizure. You'll wake up hurting all over and won't feel good for the next several days. I've done this a few times over the years by mixing pregabalin with other substances. But my doses were very high and I shouldn't have been taking so many. Usually doing something dumb like taking 15 gabapentin tablets over the course of a night mixed with whatever else I happened to have laying around.

All we can tell you is you're taking a risk. Which you already know.
 
What sort of dose would you say was responsible for seizures?

The first time I took pregabalin I took 1200mg on top of a loaf of tramadol and was totally out of it. Itm clearly overdosed myself. It was kinda fun but overwhelming. A little more and I thought maybe seizure territory.
 
What sort of dose would you say was responsible for seizures?

The first time I took pregabalin I took 1200mg on top of a loaf of tramadol and was totally out of it. Itm clearly overdosed myself. It was kinda fun but overwhelming. A little more and I thought maybe seizure territory.
I can't remember if I got seizures from the pregabalin or the gabapentin. I preferred the gabapentin and I think each capsule was 150mg or 300mg.

I would take a capsule about every hour or so with a fatty snack and soda. If you take it all at once you end up pissing out most of it but if you wait and stack them over the course of several hours you'll get more of the drug in your system. Typically, I wouldn't bother taking gabapentin unless I had at least 10 capsules. Usually I'd take more than that. Probably about 15. My doses were somewhere in the 2,000mg - 4,000mg range. Most of the time if I started with 15 capsules I'd have 2-4 left over the next morning. What would happen is eventually I'd get hit with a wave of pure sedation where I could barely walk. It would become impossible to sit up in my chair and use the computer or watch TV. At that point I'd stumble to bed and lay there enjoying the CVEs while listening to music. I'd be out of it until the next morning.

The few times I suspect I had a seizure I think it happened after I passed out and was sleeping. I woke up a few times where every muscle in my body felt like I'd been beaten with a blunt object. My pillow would be covered in drool. I'd feel awful for a few days afterwards. I can't be sure because I lived alone at the time but I'm 99% sure I induced a seizure.

These drugs are pretty safe if you take them like most people do. If you ate say 10 capsules of gabapentin at one time most of it would be wasted. Your body can't absorb it all in one go so most of it ends up in your urine. But if you stack them like I did you can get most of it to cross the BBB. That's how you end up getting in trouble.

I more than likely was mixing it with other things like benzos and opioids when I did take too much. But with gabapentin other drugs are a waste once you hit the level where it has you zonked up like I used to get. It's a unique experience and gabapentin became one of my favorites because it could get me smashed like that. You stumble around more than a drunk and you get a ton of euphoria. Phenibut can do something similar if you intentionally take too much. I did that once with phenibut and got to a similar state of mind with the lack of coordination. Your legs become spaghetti and you start shaking like people on TV do when they portray a seizure. It isn't something to go messing around with.

I would say for most people they'll never get to that point unless they intentionally overdose themselves over the course of many hours like I did. These GABA drugs seem pretty safe where the average user is concerned. It's only people like me that figured out they could stack them that get into that position.

I really love gabapentin. I like it better than pregabalin. People say they're the same but I feel like gabapentin has its own unique profile and is more fun.

1200mg of pregabalin is certainly in the same territory. It's hard to describe just how out of it you can get on the stuff. I've never seen anyone describing the type of CEVs I could get from it. It enhances music almost as well as MXE once you're up to that level. It kills all anxiety and pain. But it's dangerous when you go out that far and I'm worried about what it might have done to my brain. Having a seizure is something no one should fool around with.
 
Very interesting. Thanks for sharing.

I think when I did it I took 600mg didn't feel much so popped another two. Not long after I was way out of it.

I also like phenibut but keep my doses low-ish. Can you remember how much you took when you had the seizure like symptoms.

I don't think I've tried gabapentin. I always thought people found pregabalin better. Horses for courses though.
 
Pregabalin is more well liked because you can get to the same level of intoxication with much less material. I forget the conversion rate between pregabalin and gabapentin but I want to say it's something like three-four times more powerful by weight.

From what I've seen over the years most people claim they get the same effects from both. This hasn't been my experience. They are very close but there is something about gabapentin that feels more sedating and fun. Provided you can get to that level in the first place of course.

As I said before with both you have space out doses and stack them. My routine is something like: Take 300mg of Gabapentin and a scoop of peanut butter -> wait for 1 hour-1.5 hours -> Take 150mg of gabapentin with peanut butter and wash it down with soda -> wait an hour -> take 150mg with fatty snack and soda -> repeat until desired level is reached. Once you hit that level you'll know. It's like getting hit with a brick.

I also like phenibut but keep my doses low-ish. Can you remember how much you took when you had the seizure like symptoms.

No idea. I just remember it was a lot. I went in the tub with the little spoon that came with it. I can't remember how many scoops I ate but I knew it was a bad idea when I did it. I had a very stressful day and I didn't care if I died. Obviously I didn't die but it scared me for sure. I was shaking all over and walking down some stairs was very hard. I had to lay down and ride it out for many hours. I do not recommend trying it.
 
Thanks, nah I won't. I've got my dose pretty much dialed in. Phenibut is a fantastic tool. I don't get CEVs from it. I have on occasion used it to potentiate other drugs and then get CEVs.

But I do get good CEVs from pregabalin with the right dose. Especially with some amanita stacked on top.

Load up on pregabalin and amanitas and go for a long massage in a dark room. That's a good afternoon...
 
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