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Tramadol + 4-HO-MET?

StretchOutAndWait

StretchOutAndWait

Bluelighter
Joined
Jan 14, 2012
Messages
102
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UK
Hi,

I've never taken 4-HO-MET before and given what I've read about the bodyload, which I'm extremely sensitive to in all psychedelic drugs due to a chronic pain condition, I probably wouldn't bother unless I could take it with a therapeutic dose of Tramadol (100mg). I've happily mixed Tramadol with phenethylamines in the past (notably in the 2c family) and found it lovely, but never tryptamines.

I'm wondering whether anyone is aware of any potentially adverse consequences of mixing the two. Sorry for asking this fairly basic question - I've used the search function and can find a little info (here and here) but not as much as I hoped.

As I understand it, 4-HO-MET is a functional analogue of psilocin and so should act on the 5HT 2A and 2C receptors. As I've been fine combining Tramadol and 2ci (which acts on the same receptors), there is no obvious reason why there should be an issue with 4-HO-MET unless there is vastly different activity at the receptor, which there might be (I have no idea - does anyone?).

Assuming there isn't, then while of course anything I did would be at my own risk and drugs have unpredictable consequences, as far as I can see there is no obvious reason that this combination should be problematic. Does this make sense? Does anyone have any other information, or know differently?
 
If you've combined it with 2C-I and other phenethylamines without problems, then 4-HO-MET shouldn't be a problem. Note, shouldn't. Phens and tramadol would be a bigger risk regarding seizures.

4-HO-MET has a powerful and very energetic bodyload, but I've noticed that there's a vast difference in how energetic 4-HO-MET is with oral administration and insufflation. Insufflation gives quite a punch and hits quite fast. Orally it's not as energetic but I'd still not say it is mellow either.

Make sure you have something to do, 4-HO-MET is not a compound which is suitable for just sitting in a comfy place IME. Move around, go outside, in nature, dance, whatever.
 
Just in before the usual rush of bullshit about tramadol raising the seizure risk..

In reality, if you take an enormous overdose of tramadol - something like 800mg, then it may increase the risk of seizures in around 1% of the people who take it - almost exclusively epipetics anyway.

So that's the facts you need to know - cos whenever you mention tramadol everyone and his granny starts screaming it "raises the seizure risk dude".
 
Thanks for the responses. Just a quick update in case anyone googles this mix in future. Three of us did this - 100mg of Tramadol and 20mg of 4-HO-MET. We all felt that it was one of the most fun, exciting and beautiful psychedelic experiences we'd ever had. Lovely.
 
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