^ would you mind telling us if your liver function was ever compromised by duloxetine please Jess?
you were on it, i assume, for longer than i and would be helpful for LEgally High to make a decision.
No it wasn't. I was on it for several years and got periodic blood tests done. My liver function was always fine.
Well, until I got hep c. But that was around the time I got off cymbalta. Been off it about a year now. I still suffer from depression, but it's no worse than it was when I was on cymbalta. And it's still way way better than back when I was suicidal and I was first put on cymbalta.
I was taken off lexapro and put on duloxetine back in early 2011 when I tried to kill myself. There are lots of things that contributed to helping my depression, but I do believe that duloxetine helped. Not to an extreme extent, but a lot more than any other anti depressant is been in. Lexapro and Remeron are the two I remember but there might have been another.
It didn't stop me getting depressed but I felt like it kept me from getting suicidally depressed when I'd start to feel down. Like that it put an upper limit on how depressed I could get. Up to that limit I could still get depressed, but I wouldn't suffer from it falling into major suicidal depression anymore. So I do think it helped me. A lot more than any other antidepressant I'd tried.
I was on it for several years, my depression had gotten a lot better after my suicide attempt once I was put on cymbalta. The cymbalta played a part but there was a lot more to my getting better than just that. But anyway, I got a lot better so I got off cymbalta a year ago. And I stand by that decision. I don't feel any worse for having gotten off it. I do still get depressed, but no more so than back when I was on it.
I've seen it help to a fairly noticeable extent in other people I love who suffered from major depression where other antidepressants had failed. So I think it's pretty effective on the whole. I don't have a particularly large sample size, but I haven't seen it cause any liver problems either. I know it is a documented side effect but I've never seen it happen. But none of those people had an existing liver problem either. Now that I have Hep C it might be different if I'd tried it again now.
Hope any of that info is of any use.
Can you take Cymbalta and experience the same high or euphoria from any other drug? Like Coke, Meth, Heroin,...? Or is the euphoria not as strong anymore while taking cymbalta and using one of those three drugs at the same time?
Apart from MDMA which is well known to not work right in people who are taking SSRIs or SNRIs, I doubt it would make much difference.
I dunno about coke but I'd used meth and heroin lots of times when I was on cymbalta and I never noticed a difference.