thujone from sage

[Arts warrior]

recently after discovering that sage has a relatively high content of thujone i decided to try a pretty basic extraction. the first step was to take some sage that i had lying around in my spice rack and put some into a jar problly around 2.5 to 3 grams i really dont know i just poored about half in to a jar and covered it with 91 percent isopropyl alcohol. i then let it soak over night. the next day i poured it out through a coffe filter into a glass pyrex dish, which i then placed next to my heater with a fan on it to aid evaporation. in about 4 hours i checked and it was completly dried. i then scraped it up with a razor blade. and formed it into a little ball. today directly before wrighting this i smoked a little bit about the size of half a copper bee bee out of my hash pipe. regarding the smoke it was actually quite smooth and somewhat sweet in my opinion a verry good smoke actually. the amount i smoked produced a fairly good high but not a real trip. also im not quite sure of what forum to post this under so if a mod sees this and its in the wrong section please move. i apolgize for the length but i have not seen much information so i tried to write as much information as i could.

 

[General Patton]

I'm not too sure about the chemical properties of thujone, other than being one of the components of absinthe. I don't know if it will form a solid when evaporated from the alcohol, or if it would simply evaporate away WITH the alcohol. I recently experimented with white sage, but didn't get good results. At all. I simply soaked one gram in rum for 20-30 mins and drank the resulting liquid, without the leaves. I had such an awful stomache ache for the next day, and into the next few weeks that I wouldn't recommend ever trying it this way.

Than again the terpenes and other shit in there probably didn't help, other varieties of sage might be more pleasant-especially if you manage to bypass the oral route. Keep us updated.

 

[Qnick]

Thujone isn't volatile, I've gotten an active resin from an ethanol extraction of wormwood. It would indeed be present in the extract if it was in the plant matter.

 

[Limpet_Chicken]

Who the devil would wish to ingest a hepatotoxic GABAa antagonist and why?

Just because of its traditional use in absinthe? personally I love absinthe, and I used to grow wormwood, but I never ingested any.

It is however, good for stuffing pillows with, as is its relative mugwort, but I believe it unsuitable for human consumption, it does seem to bring vivid dreaming about when stuffed in a pillow.

Wouldn't want to stuff it anyplace else, save perhaps in somebody I dislike

 

[Mycotheologist]

Interesting, thujone is a GABA_a antagonist and 5-HT3 antagonist. That might make it useful for speeding up recovery from benzo withdrawals. I don't know how great the hepatotoxicity is though. Its far easier to get than flumazenil so if its not too harmful to the liver, then it might be worth looking into.