• REAGENT TESTING & DRUG CHECKING Welcome Guest
    Posting Rules Bluelight Rules
    Featured Link 1 Featured Link 2
  • RT&DC Moderators: Senior Staff

Thin Layer Chromatography

cuddlefish

Bluelighter
Joined
Aug 9, 2002
Messages
288
Location
Brisbane
I've recently been playing with TLC and was wondering if there was any chemistry buffs out there who know of a decent solvent combination to separate MDxx, speed and of course PMA. It just crossed my mind that many of the problems with reagent testers might be overcome by seperating the components and charing the plate with a reagent tester. Any thoughts guys?
 
There's been a few threads on this here, try the search function. I played around with TLC a few years back and had very mixed results. I found it far too fiddly for someone like me with little practical chemistry background. I know that a certain guy was playing around with different solvents types, but I didn't hear back about it. I might ask him.
 
Yeah I've read the other threads on TLC and was wondering wether someone had come up with something. The thread was meant to be a sort of chemistry buffs/student unite thing. Its amazing how much effort and research some people will put into a bulberator and yet only one reply to finding an improved testing method. A friend of mine thinks that if the ideal solvent combo can be found that it wouldn't be to much of an ask for most people if they really wanted more accurate results. He even thinks it might compete with the reagent testers as the additional cost is negligible.

At the moment I'm thinking of a chloroform/ethanol solvent mixture but I can't trial the ratios as I don't have access to a lab or mdxx substances. I also thought possibly thought a combo of isopropyl ether and acetic acid (or any mild acid) to protonate the amide groups. Like I said if there are any chemistry buffs or perhaps you've access to a lab ( not just student type access, don't go risk your enrolment), give us your thoughts, even if its just pointing me in another direction. Cheers
 
Top