Depends what is intended as comedown, coming off the drug or the way you feel the day after?
In the first case i would say high dosages of Ritalin, you feel great for about an hour then I enter the most horrible emotional state: paranoid, depressed, anxious, insecure.
In the second case the I would say meth, I get horribly depressed after a long binge. But I've found that it's mainly caused by th sleep depravation. So now i'll always keep aside a coupe lines, which i take orally for 2-3 mornings after the binge & don't feel any depression. The actual come down from Meth for me isn't all that bad, after a binge anyways I'm so tired I need meth just to stay awake, so no meth = me sleeping like a baby.