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Opioids The right dose

Whosajiggawaaa

Bluelighter
Joined
Jul 9, 2011
Messages
18,157
Location
The blanket party of the century
I was dependent on 800 to 1000 mgs of codeine for the past year and I recently acquired 70 Oxycontin 10 mgs. I made the switch on Friday and have been doing 20-40 mgs a day since instead of my usual ridiculous amounts of codeine. I wanna know how much it's safe to take to feel the best effects without over doing it as I've yet to really "feel it".

Also how long would it take to become physically dependant to oxy bear in mind I was physically dependent to codeine and had quite bad physical withdrawals when I tried to quit, would the withdrawals from 40-80 mgs a day be worse than 1000 mgs of codeine ?

Thanks in advance.
 
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Uggh, you're comparing apples to oranges. If you used to use 10000 firecrackers to blow something up, I would recommend using one and a half hand grenades. I dunno, try 30 mg of oxycodone time release to catch a good buzz?

And yes, if you take a lot of pain killers for a long time, you will have withdrawal symptoms when you stop taking them.

Say a year from now, when you've graduated to 300mg of oxy a day, you're gonna be violently ill for a couple of weeks... It'll be worse than the sniffles that happen when you stop taking a bunch of codeine for a few months.
 
Wow, what a convenient time of "acquiring" 10mg oxys. Did you steal your mom's Oxycontins that you were worried she was going to get addicted to? Or were they the ones you were "scripted"... I hope you weren't taking pbuilder's advice seriously in that thread, he was being sarcastic.

I'm going to give you the benefit of the doubt and hope you didn't steal the medications your mom needs to treat her pain, I seriously hope that's the case.
 
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Oxycontin, is the time-released formula of the opioid, oxycodone. I was mot aware of a extended release form of oxycodone in the ten mg range, seems rather low. With that in mind if you do indeed in fact have 10 mg ER(extened release) oxycodone and with a tolerance already in place 20-40 mg over the course of a day will only keep you well from the sickness. Do you have the OC or OP ER cotins? One(OC) is a lot easier to defeat the time release matrix contrasted to the OP matrix which takes some time and effort to defeat.

I have never had many chances with codeine as I HATE the massive amount of itching it would create, as does morphine. So im not sure of a "safe" dose that would allow the sought after glow of opiates/opioids. Keep in mind that if these are in fact ER oxycodones and you do defeat the time release oxycodone is a good bit stronger than codeine, just keep that in mind and start low as you can always take more in small amounts if need be.

You are not dependent on codeine per say, rather your dependent on opioids/opiates. If your sick, withdrawals, and you dont have codeine but rather hydrocodone it will stop the withdrawals. What varies is the strength, potancy, duration of these substances which in return will affect in varying degree duration and severity of one's withdrawals.
 
Wow, what a convenient time of "acquiring" 10mg oxys. Did you steal your mom's Oxycontins that you were worried she was going to get addicted to? Or was it the ones you were "scripted"... in any case, how do you have 70 if you and your mom were each prescribed 60 a month... I hope you weren't taking pbuilder's advice seriously in that thread.

I'm going to give you the benefit of the doubt and hope you didn't steal the medications your mom needs to treat her pain, I seriously hope that's the case.

What a needless post, dude asked a pretty straight forward question, I don't understand why you would be getting on his ass about it. Even if he did steal them from his mother, or anyone else, it has nothing to do with what he asked. Also, as most addicts know it isn't all that un-common for people to "acquire" drugs in a less then honorable fashion. May not be right, but it's not your place to judge, especially on an (ass)umption.

KK, now that's out of the way. OP, take your time and slowly build your dose. How much you can take before it becomes a health issue varies greatly from person to person due to tolerance, weight, ect. I personally can take 150MG of oxy and barely reach a buzz, but if I did that 5 years ago it would kill me. So start low and add say, 5 or 7.5 MG every time you feel the last dose kick in. GL/HF and be safe.

-Sunshine.
 
As someone who's had medications stolen from them, I had to put that out there for the young people lurking these boards. Didn't mean to flame the OP, but rather to let the teenagers lurking know that it NOT OKAY to steal medications, THEY will suffer. Again, not to the OP specifically, but it is more than just "not right," it's a scumbag, piece of shit thing to do if they are dependent on them.

And to answer the OP's question, 200mg codeine = 20mg oxy, but if you have CYP2D6 polymorphisms, the amount of codeine -> morphine converted is a lot higher.
 
I was dependent on 800 to 1000 mgs of codeine for the past year and I recently acquired 70 Oxycontin 10 mgs. I made the switch on Friday and have been doing 20-40 mgs a day since instead of my usual ridiculous amounts of codeine. I wanna know how much it's safe to take to feel the best effects without over doing it as I've yet to really "feel it".

Also how long would it take to become physically dependant to oxy bear in mind I was physically dependent to codeine and had quite bad physical withdrawals when I tried to quit, would the withdrawals from 40-80 mgs a day be worse than 1000 mgs of codeine ?

Thanks in advance.

If you are physically dependent to one opioid you are physically dependent to them all. It's not like you can go from being physically dependent to codeine and switch to oxy and then be able to quit the oxy without withdrawal symptoms. Unless you are saying you already quit codeine and went through WDs, and came out the other side?

It's impossible to accurately compare the withdrawal symptoms, as the severity of withdrawals generally have more to do with how often you take something and how long you've been taking something. But yes, the withdrawals are just going to get worse.
 
Holy shit... I have never actually done codeine except as a youngster, I never knew it was so weak. I understand what you are saying Ergic about not stealing drugs from moms-pops or really anyone, especially those who are dependent on them. Looks like I made the (ass)umption, for that I apologize. To magnify your point about not getting into others shit though, an immediate family member of mine got into my fathers bathroom cabinet one day and took what she thought was a couple benzo's. Around 24 hours later she couldn't get off the toilet because what she ingested was actually laxitive. The best part of this story is before her bathroom became her prison, she actually thought that she had achieved a high. Hind-sight, the dizzying affect of the laxatives onset/gastrointestinal stress was what she thought was her benzo buzz. So yeah, don't steal peoples shit, else you might shit...alot.

-Sunshine.
 
200mg codeine = 20mg oxy

That's not accounting for incomplete cross-tolerance though. Usually when someone is switching to a new opioid there will be incomplete cross-tolerance and they should take 50% of the "equivalent" dose. So if his normal dose was 400mg of codeine twice a day, he shouldn't take more than 20mg of Oxy twice a day. He can gradually increase the dose by small increments. Much safer than him thinking because he's taken 1000mg of codeine in one day before that that means he can safely take 100mg of Oxy at once. Take whatever the normal dose of codeine was at one time (not the daily total) and divide that by 10, then take half of that amount in mgs of Oxy. So if you normally take 300mg of codeine at once, 300 ÷ 10 = 30 ÷ 2 = 15mg of Oxy (you can also just divide it by 20, 300 ÷ 20 = 15). Then if that is not enough, try taking 5mg more the next time.
 
^ Agreed, but the OP has been taking 20-40mg of oxycodone and is saying that they haven't been satisfied with the high yet.
 
LOL! Hell of a story, Sunshine, and it's all good :) That's karma in full effect for your family member...

So yeah, don't steal peoples shit, else you might shit...alot.

Yeah, this is basically the point of Bluelight, to help each other avoid shitty situations. Kids, don't steal medications! Seriously
 
To the OP, the oxycodone will have a somewhat different feel than the codeine, but since you were dependent (addicted?) to codeine you were/are already opiate-dependent. You see, with opiates (natural/semi-synthetic), if someone is addicted to one opiate, another can be easily substitued, as mentioned above. In almost all cases an addict with an addiction to one opiate will not pass up another one. Opiate addiction is fairly straightforward in this regard when it comes to opiates that are natural or semi-synthetic w/o odd properties, these natural/semi-synthetic opiates include morphine, heroin, codeine, oxycodone, hydrocodone, hydromorphone, oxymorphone, and others. If you are not "feeling" the OxyContin (oxycodone ER), it is fairly safe to increase a bit in your daily dose until you get to a place where you feel comfortable. You have the 10 mg strength, so you can adjust the dose carefully. But, let me just say that high dosing with oxycodone (with tolerance, of course) is fairly easy provided you have enough $/steady supply. Dosing high with codeine (above what you are currently doing) becomes an issue because of the APAP (even w/ CWE), the caffeine, the CWE processes, and a ceiling dose area which you might hit. You would also need a much larger number of pills themselves to sustain a larger opiate addiction. And, if you start getting involved with oxycodone, you might find you much prefer it over the codeine, and this could lead to a heavier addiction, higher tolerance, and ultimately more unpleasant effects brought on by addiction. If you are going to play with opiates fine, just know that you are playing with fire, and how to reduce the risks of getting burned. I like opiates myself, and I don't judge about that, but I do believe being educated makes all the difference. I also have to agree with ErgicMergic in that it seems a little suspicious you got these 10 mg OxyContin (not a very common strength rx'd) so recently, after making a post about your mother's pain management with OxyContin 10 mg. I don't judge there, because it is not my place, but I will say opiates make life tolerable, even enjoyable for those who suffer from agonizing pain and would otherwise be bedridden and depressed/anxious. I have stolen a FEW Percocets and a FEW Lortabs out of medicine cabinets before, but they were not being used and the script was no longer needed for the patient. Of course, it is still theft, and the same in the eyes of the law, but there is a difference. Just be safe, and try to make sure you aren't mistreating others around you. I am not trying to preach, or maybe I am. Like I said be safe, educate yourself, the whole nine yards. There is always more to learn.
 
I was dependent on 800 to 1000 mgs of codeine.

Impossible. Your body can only metabolize 400mg max. Anything more is a waste.

Since you were dependent on codeine, you are addicted to opiates. Therefore, you are already dependent on Oxy and will experience withdrawals.
 
Thanks for all the information peeps :)

I'd like to clarify that I'd never steal from my mother, she and I are close and the Oxy's made her very nauseous so she didn't wanna continue with them so she traded them for some of my muscle relaxers and benzo's (slightly dysfunctional lol) and she is going back to the neurologist to get something else.
 
With a low tolerance, the sweet spot you're looking for would be 30mg-50mg. It sounds stupid but it's really hard to get your dose with opiates just right so you're high and feel good, but not completely nodded out. It's like goldy-locks.

To answer your question about the comparative withdrawal between codeine and oxycodone, there are charts and other useful tools for comparing dosages of different opiates and different routes of administration. I'd include a link, but you can just google it pretty easy
 
Impossible. Your body can only metabolize 400mg max. Anything more is a waste.

Since you were dependent on codeine, you are addicted to opiates. Therefore, you are already dependent on Oxy and will experience withdrawals.

That was over the course of an average day taken in increments usually 250 x 4 or 200 x 4. Doubt that threshold applies as I felt every dose.
 
That was over the course of an average day taken in increments usually 250 x 4 or 200 x 4. Doubt that threshold applies as I felt every dose.


Look at my Location, OTC codeine phosphate here is w/o rx.

I was 2 years 8 x 30mgs = 240 mgs Minimum 4 to 5 times a day, so don't let anyone tell you about the ceiling effect.

Until your sitting there with 30 tabs a day, it a real pain to us... I just came out of rehab for 150mgs per day Hydrocodone Abuse
3 years ago and I did 2 years of Codeine Phosphate ...

let me do my MS i'll BRB
 
As someone who's had medications stolen from them, I had to put that out there for the young people lurking these boards. Didn't mean to flame the OP, but rather to let the teenagers lurking know that it NOT OKAY to steal medications, THEY will suffer. Again, not to the OP specifically, but it is more than just "not right," it's a scumbag, piece of shit thing to do if they are dependent on them.

And to answer the OP's question, 200mg codeine = 20mg oxy, but if you have CYP2D6 polymorphisms, the amount of codeine -> morphine converted is a lot higher.

I'm in the same boat as Ergic. I've had meds stolen from me. Long story short, I had to go through benzo withdrawal because I had meds pilfered from me. Stealing someone's meds, especially when they're dependent on them is a fucking lowlife thing to do. Put yourself in their shoes and try to imagine what they're feeling when a) they feel violated because someone stole from them and b) any withdrawal effects from not having their medication.

EDIT: Now the OP's saying that he traded the meds with his mom? Wtf?

God this thread made me facepalm hard...
 
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Hydrocodone is six times stronger by weight than codeine, hence the brand name "VIcodin". Using our equivalent dosage of hydro, one may calculate oxycodone doses by applying this simple ratio. 5mg of oxycodone is equianalgesic to 7.5mg of hydrocodone.

Without accounting for aforementioned incomplete cross-tolerance and CYP2D6 polymorphisms:

400mg codeine ceiling dose / 6 = ~67mg hydrocodone. Multiply by 2/3 and estimated amount of oxy is 40mg. This is nowhere near final, read above this post to discover why.

Extended release preps left intact involve further calculations, ask somebody else to determine how much Oxycontin is necessary to match 40mg at once.
 
can someone tell me where it says I jacked them from my mom, So i can put my 2cents in for the OP... im looking but I can't not see... well also i'm just skimming

anyways yesterday I went from 125 mgs of MS XR & 20MGS METHADONE, in the morning to at night 100 MGS of MS XR

I woke up with a stiff back, some muscle pain from other situations...

i have 20mgs again from the Mdone Clinic but i want to save them

I just took 80mgs of MS XR to see what will happen, do you think that will be ok to taper today maybe best because I only have 800 Mgs of MS HCL XR left
 
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