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  • BDD Moderators: Keif’ Richards | negrogesic

The Official Tramadol Discussion Thread

NCUK said:
why?
ultram never got me high in the least bit, ive also heard tram. has over 1000 times less euphoria, resperatory depression, basicly the good effects people take opiates in the first place. why take such a large dose of a drug that in the end may cause u serious harm.. ie siezures and all that good stuff. the euphoria u r feeling is pure placebo


TRAMADOL HCL = POO
Click to expand...

WRONG! Just because YOU get no effects does not mean others get no effects. You must be one of the unfortunates that do not produce the enzyme to make tramadol work to it's fullest effect. Of course it only takes a few minutes reading to discover that information.....
 
we should not bother responding to these types of posts. it only makes it harder to read through this thread. there were probably 2 or 3 pages in here, collectively, regarding this issue. can we ignore it and continue our tramadol discussion as normal?

on that note, today i took 150mg of tramadol when i woke up. when i wake up, every day, i am depressed, and do not want to do anything. sure, i have cravings to pop norcos or some other opiate/opioid, but all in all i just feel like a depressed piece of crap! i'm sure most of this is due to my recent addiction to benzos, which i am slowly tapering off of, along with perhaps a tramadol addiction.

to me, tramadol is a fantastic antidepressant, and it helps my back pain. when i took the 150mg of tramadol, within 15-20 minutes i felt normal, even better than normal! whereas yesterday, i took a very high amount, above the risk of seizure (which, again, is 400mg throughout a 24 hour period). i found it to be a complete waste other than the fact that it lasted over 12 hours (analgesic, antidepressant).

either way, i could have just woke up and taken 150mg like i did today and maybe redose that once or twice, if i even need to. i just wanted to throw in my experience of a massive, dangerous, tramadol dose. it didn't work for me. keep in mind that i consumed a hefty amount of benzos including clonazepam, diazepam, AND alprazolam. this is not normal for me, i just didnt want to have a seizure and investigate high doses of it.

as for the people complaining about constipation, drink water. drink more water then. after you drank all that water, why don't you go sit down, and drink some water. when you're finished with that, have a drink of water. you get the idea, it will make a huge difference, whether it be tramadol, poppy tea, heroin (no experience firsthand), methadone, or whatever.

but please, to anyone who reads this thread and decides to complain/rant about how tramadol is garbage/etc without good advice or any type of significant contribution to the thread, why don't you post something helpful somewhere else.
 
I agree that not responding would probably be the best thing to do. My problem though is when I see shit like "tramadol doesn't work" or "tramadol can't get you high, its a placebo" I just have to respond with the facts, facts that are indeed available HERE with just a few minutes readng. I can't believe the number of people who respond to this thread in a negative way, who apparently have not bothered to read anything on this thread. Tramadol definately works on me and has for the past 10 years, with some hydro/oxy time thrown in. My tolerance is sky high but I still get great affects so I will continue. Fact of the matter is that I prefer tramadol over hydro and oxy. I like the mood lift and the small amount of euphoria it has due to its extended time.
 
A lot of people do not understand, as I didn't at first.
If your tolerance to opiates are higher than max codeine level, then without potentation, it is very hard to get high on less than 400mgs of tramadol. Your liver enzymes are depleted from another opiate/opioid that converts just like tramadol to a stronger drug, leaving little to no tramadol being converted to O-desmethyltramadol, which is what is sought after.

Now, if I had 300mg of tramadol, I would not get high for the life of me.

People like me would need an enzyme inducer, not a blocker.

Anti-histamines (blocker) cut out these enzymes as well. These will not help you in the slightest bit if you are trying to potentate any opiate/opioid that has little or no action in it's parent form.
Taken too soon after, and they can slow conversion to a crawl or stop altogether.

So, with the right knowledge and tools, there is no excuse not to get high on tramadol.
 
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today i took about 2mg of bupe instead of taking tramadol. when i first woke up i took 150mg and then the bupe right after. the antidepressant effects of tramadol kick in fast and i feel fantastic again, later the bupe kicks in and i feel very nice.

when i got home from work, i felt like shit, not physically at all, im still high on bupe. just lots of depression, pretty damn bad, too. i just took 200mg because i dont feel so well mentally and i dont think id be able to sleep. if in the next half hour i am happy, then ill know im pretty dependant on these things and should consider tapering off.

if this is a minor withdrawal from tramadol i couldnt imagine an extreme dose withdraw. it has been not even fifteen minutes and i already feel better. to me, tramadol is an extemely fast acting SSRI and SNRI. it's almost like a happy pill, with awful withdrawal symptoms. insta-prozac.

i had the same effects from prozac i remember. when i took it within hours i was happy and content but felt weird and couldn't get my cock up. i wonder if that would have the same type of withdrawal symptoms. i may have to consider getting a script for either of these from a physician, especially considering, from what i have heard, it is now on the DEA watchlist.

someone mentioned before, "stock up". i'll try and take his advice.

benzos dont even seem to help with depression with this one, i think it makes it worse even. 2mg of bupe with no tramadol and i was pretty damn sad, yet comfortable. comfortably... depressed as hell.
 
wow about a half hour after i took 200mg of tramadol i feel like im on heroin and a small dose of MDMA. i felt depressed as SHIT before i took them. bupe + tramadol is like oxy and mdma. very addictive, and the withdrawal is awful from tramadol. i definitely need to taper off this. either way im nodding after a few tokes and feel amazing. sounds like you pillthrill, only i get the withdrawals BAD.
 
Yeah I hadn't done E until recently and I totally agree. I also introduced my bf to it and with some weed he said it felt that way as well. Guess we are the lucky ones. Although I don' t have withdrawals I feel strange without it and it takes awhile to get back to functioning sober.
 
What is this about antihistamines blocking the conversion of tramadol to its metabolites? I would like to hear more about this.

I get that if the AH is metabolized by the same enzyme, the tramadol and the AH will "compete" for conversion. But are all AHs converted by the same enzyme as tramadol?
 
Wings of wax said:
What is this about antihistamines blocking the conversion of tramadol to its metabolites? I would like to hear more about this.

I get that if the AH is metabolized by the same enzyme, the tramadol and the AH will "compete" for conversion. But are all AHs converted by the same enzyme as tramadol?
Click to expand...

I recommend taking a look at the opiate/opioid potentation thread.

Look at it from this angle: You need the codeine (prodrug) to turn to stronger metabolites in the liver to get high, right? This same thing applies to tramadol and the other handfuls of weak to no activity opiate/opioid prodrugs.

(Most) Anti-histamines are inhibitors of the liver enzyme CYP2D6, which is necessary for the conversion to stronger metabolites to get high or even work for that matter. So cutting into your enzymes will diminish the amount converted, and prolong the effects. (If you got any.)
This is good for other opiates/opioids that do not have to be converted to have an significant effect.
 
Then I really need a list over which AHs are metabolized by CYP2D6, if that is the enzyme that tramadol is metabolized by.

I will have a look at the potentiation thread.
Stumbled over this:
http://www.ncbi.nlm.nih.gov/pubmed/11936702

Also, promathezine comes in a combination with codeine, which wouldn't make much sense, since codeine is metabolized by CYP2D6 as well. This must be a complex issue.

Any insights are welcome!
 
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Wings of wax said:
Then I really need a list over which AHs are metabolized by CYP2D6, if that is the enzyme that tramadol is metabolized by.

I will have a look at the potentiation thread.
Stumbled over this:
http://www.ncbi.nlm.nih.gov/pubmed/11936702

Also, promathezine comes in a combination with codeine, which wouldn't make much sense, since codeine is metabolized by CYP2D6 as well. This must be a complex issue.

Any insights are welcome!
Click to expand...

Against many peoples belief, I still think that promethazine is there not only to boost painkilling property and reduce nausea, but at the same time kill the euphoria if a high enough dose is taken. It makes the codeine feel dark and gloomy, not warm and sedating.
The bolder bit is what most do not believe.
 
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Jay: So you would stay clear of promethazine while taking tramadol?

I was thinking that it could be an idea to take some promethazine after the tramadol has been metabolized (a couple of hours). What do you think?
 
Promethazine after a couple of hours is good. This may be a problem for people with low seizure thresholds when combining two drugs that can lower it even further.
No high on tramadol is seizure proof. I still don't see how people are surprised when they do seize.

Taking it 30mins before is just absurd.
Taking it at the same time is also just as bad.

I would love for people to get their technique down for every single drug they do.

Every drug used for recreation has potential to be "emphasized" to make the best of the high.

Tramadol is the perfect example. As we all know, some drugs just take a (very small, but bigger) effort to use recreationaly for the best results.

As I said before, tools and knowledge make the best high.
 
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i like promethazine is OTC here and goes down well - i never have any problems using it with tram , but then again i can take fairly high ammounts and not get anywhere near a seizure - just because thats how it is for me - doesnt mean that its safe for everyone to do so

has anyone noticed how taking tramadol (esp high ammounts ) makes it really difficult to come ?
 
Free_Man** said:
i like promethazine is OTC here and goes down well - i never have any problems using it with tram , but then again i can take fairly high ammounts and not get anywhere near a seizure - just because thats how it is for me - doesnt mean that its safe for everyone to do so

has anyone noticed how taking tramadol (esp high ammounts ) makes it really difficult to come ?
Click to expand...

SNRI--------------------> No cum for you buddy.
 
Tramadol is defenitely a worthwile opiate to include in any opiate users menagerie or drugs on a cycle. Its always been a good stop gap for me, in between oxy and codeine. id say its more useful than codeine because there is no ceiling effect, but ive only once had anything like a seisure or nasty ssri effect, and that was at 2500mg+ in one go, after about 4 months of daily use when tramadol was the ONLY opiate available. My fine motor skills dissappeared and i could hardle pop out the couple of valiums from the packet that i needed to stop that awful feeling, but they did.

But being a lone opiate its strange that they arent an s8 in australia like oxy and morph. come on, if 30mg codeine tablets on there own are S8, why not tramadol? its kinda like doloxene, the same loophole.

Id never take that much tramadol in one go again, but i think its pretty reasonable to use 800mg at a time with a benzo if youve got a habit. Am i the only one who doesnt get an SSRI effect or bad reactions from this level?
 
Everyone get's a SNRI effect from tramadol. Not just you.

Your fine motor skills were destroyed because you were shaking from noradrenaline.
You even said it yourself that you had a reaction before.

And it is not in between Oxycodone and Codeine. More like Darvon and codeine.
And tramadol inhibits GABA-A at those doses above 400mgs.
 
I just got some tramadol 50mg. and I took one and it made me feel a little funny so I guess my question is WHEN will I feel the high? Do I have to take a few like 1 or 2 every 4-6 hrs. over the course of a couple days or what to feel the buzz???
 
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