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Gabapentinoids The Lyrica (Pregabalin) Mega Thread v 2.0

Is no one else worried about cognitive and memory side effects? The only time I took this shit was at relatively high does for like 3 days in row with alcohol and I'm still worried I may have permanently changed/damaged my brain somehow. If anyone knows anything about this please let me know
 
^ How long has it been since you last took it?

Alcohol+Lyrica can cause cognitive impairment, especially at high doses, but this is only temporary.. These effects shouldn't last more than a couple of days at most.
 
mikehunt73 said:
Is no one else worried about cognitive and memory side effects? The only time I took this shit was at relatively high does for like 3 days in row with alcohol and I'm still worried I may have permanently changed/damaged my brain somehow. If anyone knows anything about this please let me know
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Just relax dude you will be ok. you're going through rebound anxiety from stopping lyrica.
 
Lyrica is a life saver drug. Almost too good to be true at first. But I have not had one full rested night of sleep ever since i stopped it. So now I am back on it. Like I said when I take it, it always works. But i have to take it everyday like antidepressant medication.
 
7nos-SS373dOH said:
^ How long has it been since you last took it?

Alcohol+Lyrica can cause cognitive impairment, especially at high doses, but this is only temporary.. These effects shouldn't last more than a couple of days at most.
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No see this was 3 months ago. My memory was pretty fucked for a good week or so before it started improving, but i'm just going through this horrible period of anxiety that I may have permanently changed my cognitive functions in some subtle way. I feel like the drug hasn't been studied enough for people to fully know what they're talking about.
 
Hello, everybody I got two questions regarding lyrica and opiates. I was using lyrica to help the withdraw symptoms due to my opana script running out 2 weeks early. I used 600mg of lyrica the first week. And week 2 I used the lyrica more for recreation and used high amounts ranging from 1g to 2g. Here is where my question comes in. I get my opana script filled tommr. Will I have withdraw symptoms from quitting lyrica cold turkey from a 2 week binge on it. Also If I do experience withdraw symptoms from lyrica will the opana help combat them? Sorry 1 more quick question. If the opana does not help should I start a taper with lyrica?
 
^imho a two wk binge on lyrica shouldn't be quite enough to experience wd symptoms, stretch it out any longer though & your sure to feel somewhat out of sorts.

Many may disagree as you were taking up to 2grams in the second week, it's all subjective,- you may experience severe wds, then again, feel no difference once back on your opiate.

Personally, I used pregabalin for 'bridging' for a week or two most months for over two years, (when I started to have opi issues). Did more good than harm I can tell you!!

If the Opana doesn't make you feel as 'good' as usual, try 3-600mg lyrica as well,- you'll soon know if you need a low dose to prevent pregabalin wds, (of which I've never experienced).

Let us know how it goes,

Rtp
 
I'm considering dropping my daily pregabalin use from 150mg to 125mg per day this week, as I'm ill with an infection so I've taken a week off work (I'm on it for anxiety, it does nothing except keep my out of WD's, I'm tolerant, been taking it at various doses for 5 months).

I will need to be back at work in 7 days time (next Tuesday). From your experience do you think this would be enough time to deal with any anxiety from the drop and for my body to readjust to a new baseline? I have an anxiety disorder and can't cope with work if I have worse-than-baseline anxiety (am struggling even at a baseline level, but I want to get off the pregabalin, as it affects my libido and causes some genital numbness).

When I've dropped 25mg in the past, I don't think I've felt any WD for about 4 days and then only mildly, lasting 2-3 days. Which would just about put me in the clear. However, I've had more serious WD (from taking higher doses) a couple of times since then so I might be more susceptible now.

I'd be interested in any comments. Thanks.
 
Spurs_1882 said:
I'm considering dropping my daily pregabalin use from 150mg to 125mg per day this week, as I'm ill with an infection so I've taken a week off work (I'm on it for anxiety, it does nothing except keep my out of WD's, I'm tolerant, been taking it at various doses for 5 months).

I will need to be back at work in 7 days time (next Tuesday). From your experience do you think this would be enough time to deal with any anxiety from the drop and for my body to readjust to a new baseline? I have an anxiety disorder and can't cope with work if I have worse-than-baseline anxiety (am struggling even at a baseline level, but I want to get off the pregabalin, as it affects my libido and causes some genital numbness).

When I've dropped 25mg in the past, I don't think I've felt any WD for about 4 days and then only mildly, lasting 2-3 days. Which would just about put me in the clear. However, I've had more serious WD (from taking higher doses) a couple of times since then so I might be more susceptible now.

I'd be interested in any comments. Thanks.
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drop the dose if take only 1x use it before bed to get sleep. I cut down my lyrica use by only taking night dose... Its the only that really matters... Take during the day only u suffer wd, take all day = overall effect diminish, one dose at night = hit u hard good night
 
^ Well dropping 16% of your dose could have some effect.. I would think 7 days would be enough to recover. Is there a specific reason you want to drop your dose?
 
I used to take 300mg a day I dropped to only 100mg bedtime then Then 50mg bedtime next few days.... Another trick is drop 100% of your dose few days at least 3-7 and when you feel the worst possible, take the lowest dose possible and it will work better than your previous doses ever did... You just reserved tolerance and sped up tapering process by going cold turkey.

Never been a fan of tapering but if you do, just go cold turkey off the higher doses then resume a taper few days after the worst wd symptoms over...

For example if you take heroin, stop completely for 5 days, then resume taper process...

I call this the "just get it over with" method, by the time you tapered down to 0 your body will be free of paws as well. If you do regular taper, u will feel a bit crap with dose decrease, then paws following week... Why draw out the pain?
 
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^ well he's not trying to quit completely.. Still waiting on word as to why he wants to lower his dose in the first place. But his anxiety is at a level in which cold turkey would be problematic.
 
7nos-SS373dOH said:
^ well he's not trying to quit completely.. Still waiting on word as to why he wants to lower his dose in the first place. But his anxiety is at a level in which cold turkey would be problematic.
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One can train themselves the suffering brought on by withdrawals of cold turkey. What I did in a matter of days one can taper off in a month...but I did if in a couple of days and I'm ready to use again! I use drugs a lot then stop completely, suffer, then repeat, it's part of the process. I have never been able to taper, it's like, "okay I dont feel good, this sucks, I might as well just go all the way since I'm not having a good time"

Yes I might be bias because i could never tapered off in my life. If I have any drugs left to taper , I will just use them to get a buzz. When I run out, I can withdraw. After so many withdraws you become used to it. There's nothing "problematic", accept the suffering is part of life, in exchange for happiness .
The beauty in this there is no uncertainty, you know when you use, you feel good, your day will be great. When you don't, your day will suck. Thats called being completely control. More control than non drug users, they could have a loss of a loved one and they will be sad. But me, a drug user? No my day will be great NO MATTER WHAT unless I decide not to make it that way!

Tl:;dr go cold turkey, if you suffer..keep going till ur 100%...then go use a lot and ct again, and again till you no longer perceive it as suffering!
 
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7nos-SS373dOH said:
^ Well dropping 16% of your dose could have some effect.. I would think 7 days would be enough to recover. Is there a specific reason you want to drop your dose?
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Thanks for your post. Two reasons:

1. It's not giving me any anxiolytic effect, and hasn't done for a couple of months, and I don't want to raise my dose to get this, because eventually tolerance will catch up. So there's no point being on it- the longer I stay on it, the worse WD will be. I don't often get an opportunity to have 7 days without working so it's a good opportunity to take the hit of some of the anxiety. Better to do a bit of the taper when sick than when on holiday and potentially ruin part of the holiday...but my anxiety is such that I can't do it whilst working.

2. As I mentioned, and despite it not doing anything positive for me, I'm sure it's giving me sexual side effects. Reduced libido, and reduced genital sensitivity, and sometimes other stuff. It's not so bad that I can't function sexually (which was true at the higher doses) but it's rather annoying, when I'm not getting anything good "in exchange".

At the same time, I really don't want my anxiety to be above baseline in a week's time when I return to work.
 
Sobrietysucks said:
One can train themselves the suffering brought on by withdrawals of cold turkey. What I did in a matter of days one can taper off in a month...but I did if in a couple of days and I'm ready to use again! I use drugs a lot then stop completely, suffer, then repeat, it's part of the process. I have never been able to taper, it's like, "okay I dont feel good, this sucks, I might as well just go all the way since I'm not having a good time"

Yes I might be bias because i could never tapered off in my life. If I have any drugs left to taper , I will just use them to get a buzz. When I run out, I can withdraw. After so many withdraws you become used to it. There's nothing "problematic", accept the suffering is part of life, in exchange for happiness .
The beauty in this there is no uncertainty, you know when you use, you feel good, your day will be great. When you don't, your day will suck. Thats called being completely control. More control than non drug users, they could have a loss of a loved one and they will be sad. But me, a drug user? No my day will be great NO MATTER WHAT unless I decide not to make it that way!

Tl:;dr go cold turkey, if you suffer..keep going till ur 100%...then go use a lot and ct again, and again till you no longer perceive it as suffering!
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I can sort of understand where you are coming from. I used to think somewhat in that way. But I am not using pregabalin recreationally, so I don't think it applies. As a side point, I think you'd still feel the loss of a loved one, there are certain pains you can't escape through drugs, and probably for good reason.
 
Last night iI took 425 mg Lyrica and my usual 2 mg Lorazepam and I slept like a corpse! This morning I feel the same exact hangover as when I drank alcohol every day. It kinda sucks, but I've been tapering off oxycodone for a while now and right now I have no cravings for oxy, just a hangover.
 
Random question - curious if anyone ever experienced anything similar:
8 year 500mg daily Codeine addiction here.
Discovered Lyrica from the GP for anxiety but discovered quickly how great the 400-500mg made me. Was great at potentiating opiates as discussed here many times!
But as with many here I had the problem of tolerance! - 2/3 days in a row would mean no more Lyrica fun until I waited for tolerance to drop. Did this for 2 months.
Then went CT on the codeine. Difference is this time I had the Lyrica (which I'd read here could help with the WDs) and it helped massively in the higher doses. Stopped taking it a week into WDs as the worst were over.
Fast forward 2 months in with no opiates and I found my old Lyrica box and popped a couple to see what would happen! As expected; it got me trashed. It was awesome.
So I had some again. And again. And again.
Now I'm 2 months on (4 months since opiates) and haven't built any tolerance to Lyrica. Heck; 100mg (my rx'd dose) gets me completely trashed every day and 600 is an almost scary level of wasted. Day in; day out.
What I'm curious of is if this has happened to anyone else or what the thoughts may be on this as to why? I'm not complaining at the lack of no tolerance but at the same time very curious as to what may of changed in my brain at what level to allow this to happen!
 
Just curious as to how those people useing this for anxiety find it? I'm on 50 mg valium a day for the last 2 years before that a big taper off zanax. Is it worth even asking the doc about with my current benzo tollerence its been bugging me for a while now so i thought i'd put it out there.
 
S.M.F.G said:
Just curious as to how those people useing this for anxiety find it? I'm on 50 mg valium a day for the last 2 years before that a big taper off zanax. Is it worth even asking the doc about with my current benzo tollerence its been bugging me for a while now so i thought i'd put it out there.
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IME it works well for a while but does not take long to get tolerant and then it does nothing except keep you out of WD. I've tried using it more on a PRN basis but that led to rebound anxiety after a while. Overall I'd say it's like benzos, good for short-term anxiety but in the long-term will just get you dependent and no longer help with anxiety, unless you keep upping the dose, and 600mg per day is the max dose, which you can get to very quickly.
 
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