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The Large and Nifty Not-quite-advanced Drug Chemistry, Pharmacology and More Thread

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I remember it being announced about a month beforehand that they were going to be scheduled.

How vendors get rid of their stocks I have no idea...
 
This has nothing to do with pharmacokinetics. This is toxicology or pharmacodynamics.

It's thought that 4-FA is not a neurotoxin, at least from studies done on rats. UTFSE for older threads on the topic.
 
How many moles of ethanol are in a liter of 40% ethanol-by-volume beverage?

This is not as simple a question as it may seem. A liter of 40% ABV vodka does not contain 400 mL ethanol, so volume times density divided by molar mass will give the wrong answer (6.85 moles).

If I simply could find a reliable source that gives the specific gravity of an arbitrarily small quantity of unflavored 40% ABV vodka, then the calculation becomes simple.
 
Enkidu said:
Haha, it doesn't? what does it mean then...
Click to expand...

It means that ethanol occupies 40% of the volume.

But since ethanol and water are miscible, what you have is a fluid matrix of discrete ethanol and water molecules forming and breaking dipole bonds at a temperature-dependent and concentration-dependant rate.

In short, if you stir 4 mL of ethanol into 6 mL of water, at STP, you will form a solution that will be less than 10 mL in volume (even though no mass was lost), and thus more than 40% ethanol by volume.

And by analogy, a liter of 40% AVB vodka has less than the mass equivalent of 400 mL ethanol in it.
 
i was wondering what sweetener is used in adderall IR tablets and when looking at the pill ingredients/excipients i could not find anything that would contribute to the sweetness aside from the saccharate and aspartate salts of dextroamphetamine...possibly? or is the sweetener just not listed, anyone know the answer to this?
 
ebola? said:
that saccharide salt should do the job: saccharine is several times sweeter than sugar by weight.
Click to expand...

pill12834-1.jpg
amphetamine-dextroamphetamine15mg-bar.jpg


Orange is sweet. Blue is pill-flavored. I dissolve them under my tongue repeatedly. There's gotta be extra sweetener added to orange.

Look at it this way: the orange (a 15 mg Barr) has about 4.6 mg 2.3 mg saccharate and 1.7 mg aspartate. A packet of Sweet 'N Low has 1 gram saccharine. What is the sweetness of 1/200th of a pack of Sweet 'N Low?

Edit: The sweetener is lactitol.
 
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seep said:
pill12834-1.jpg
amphetamine-dextroamphetamine15mg-bar.jpg


Orange is sweet. Blue is pill-flavored. I dissolve them under my tongue repeatedly. There's gotta be extra sweetener added to orange.

Look at it this way: the orange (a 15 mg Barr) has about 4.6 mg 2.3 mg saccharate and 1.7 mg aspartate. A packet of Sweet 'N Low has 1 gram saccharine. What is the sweetness of 1/200th of a pack of Sweet 'N Low?

Edit: The sweetener is lactitol.
Click to expand...

i had suspected a sweetener in the orange adderal for some time now. I guess a smidgin of lactitol makes the medicine go down these days. How else are we to keep children on speed?
 
First off, for various reasons, I don't want to cause any permanent neurotoxicity to my brain. Most people say this, but I'm really quite serious about not messing with neurotoxic substances (however tempting it may be to do so). I'm even hesitant to take prescription-strength dosages, because (in my opinion) a slight negative change over a long period of time is a big deal.

I am going to etdPOP(a large electronic music event/rave which is 10+ hours long) at the end of May, and I have heard good things about adderall in settings like this (energy, euphoria, etc)

Would IR or XR be preferable for a setting such as this? I would consciously keep my body temperature down, and coudl take vitamin c/others if needed. Most importantly, is there a chance of suffering even slight neurotoxicity at this dosage level of 30mg, provided that I keep my temperature down and follow any other prevention measures you guys suggest?

As a separate question: do you think it's worth doing it?
 
I need some info on the side effects of methylon, butylone and of methylone & butylone together. Are they known to produce intense rushes of pain, numb & sore arms and legs like cut off circulation, painful psychosis and a slow onset of stupor . If 1 where to fall asleep in this state would that be as safe as staying awake?
Thank you.
 
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I meant to say I need info on these compounds.
Is M1 accumulative.
the M1 and B1 I am talking about both looked smelled and tasted pretty much the same...
Mephedrone and methedrone are good Butylone and Methylone are like poison.
I can not beleive this feeling, if I don't log on tomorrow, I'm prolly dead.
Thank you.
 
I think you're having postual hypotension and absurd panic attacks and stimulant psychosis and malnutrition. Errr. so fo' sure you're killing yourself. Please go to the hospital? If you still can.
 
Hi. I have a quick and not so advanced chemistry ? that has nothing to do with drug synthesis per se for once.

benzene --> phenol

is a facile enough transformation i guess as it involves the thermodynamically favorable process, ie exothermic oxidative combustion of a simple HC by O (ie, 'burning'), but what about its reverse rxn?

benzene <-- phenol

I have always been under the impression that this pathway is all but impossible but <vecktor> has recently mentioned something involving OTT leaving groups and thallium that has my curiousity piqued. Is this reverse rxn feasible chemically and if so how specifically? thx.
 
originally posted by hamhurricane:

Does anyone know of a clandestine chemistry lab run by a female?

Yes, plenty. Happens all the time. It's a lot easier to pull of crafty high risk high drama sleights of hand like that when you seem so young and innocent and are also not The Man in charge of the department.

What are little girls made of? Sugar and spice and everything nice!
 
The wikipage on Kanna says that it should not be combined with SSRIs MAOIs, cardiac medication and psychiatric medication in general. I can't find the reference for that statement and I don't understand why it shouldn't be combined with psychiatric medication and cardiac medication and more specific, what kind of medication in these two groups it shouldn't be mixed with. Hope this is the right place.

The SSRIs and MAOIs I can understand, but the others? Can anyone enlighten me?
 
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