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The End of Opiate Withdraws with Low Dose Ibogaine and Memantine...Yes, Really!

Workin2005

Bluelighter
Joined
Apr 30, 2011
Messages
61
Here are excerpts taken from a journal of a friend of mine who used Low Dose Ibogaine and Memantine to overcome an opiate addiction and the terrible withdraws that come with it. I hope it helps others that are dealing with the horror of addiction and the hell of opiate withdraw. There is hope!

A quick background of my friend. I'll refer to him as "Bob".

Bob started an addiction to pain pills (vicoden, oxy, Opana) about 2 years ago. It went from a few vicodens a day and progressed to about 120-180 mgs of oxycodone per day. Bob got to the point of taking his last dose around 7:00 at night, then waking up around 2:30 in the morning in withdraws...cold sweats, restless legs and just that in ability to fall asleep without another fix. His motivation to work or get anything productive done was gone. His relationships suffered greatly and his life revolved around finding a way to get his next fix.

He thought about Suboxone treatment, but didn't want to trade one addiction for another. As many people know, coming off Suboxone is almost as painful as withdrawing from other opiates...something the Suboxone Doctors don't like to tell you.

This is when he started studying Ibogaine and Memantine. While Ibogaine is illegal in the USA and Memantine is very hard to get a prescription for, as most doctors have little sympathy for opiate addicts, especially when they aren't going to be making much money prescribing Memantine. They push suboxone because this ensures the doctor will keep you coming back and paying your hard earned money to them.

Both Ibogaine and Memantine can be found online, without a prescription, from reliable sources if you search hard enough. The Ibogaine used in Bob's experiment was the HCL form. It comes in 3 forms, HCL, TA and Root Bark. The best and most potent of the 3 is the HCL.

Bob started by cutting down his dose of oxy from 180 mgs to around 100 mgs per day. This was not enough to get him high, but enough to keep him out of withdraws.

Day 1: After receiving his Ibogaine and Memantine, he begain first thing in the morning, before taking any oxy, by taking a 5 mg of Memantine and about 30mgs of Ibogaine HCL on an empty stomach. This was to test and see if he had any allergies or adverse reactions to them. A slight stimulant effect was noticed from the Ibogaine and no real effect was noticed from the Memantine. 3 hours after, Bob took his usual doses of oxy throughout the day. No real changes where noticed.

•VERY IMPORTANT...be sure to wait at least 3 hours after taking Ibogaine before taking ANY opiate. Everyone is different and it's possible that the potentiating effects of Ibogaine could cause an overdose of whatever opiate you take. Until you know how this effects you, start with taking half of your usual opiate dose 3 hours after the Ibogaine and assess the results. Please be careful!

Day 2: Bob upped the dose of Ibogaine to 50 mgs first thing in the morning on an empty stomach. He also took 5 mgs of Memantine in the morning and another 5 in the evening. The Oxy was taken as usual.

This went on for 5 more days. Bob was still waking up in withdraws in the middle of the night for this first week but did notice they weren't nearly as bad.

Week 2:
Bob upped his dose to 100 mgs of Ibogaine first thing in the morning on an empty stomach along with the 5 mgs of Memantine in the morning and another 5 mgs in the evening. The Ibogaine definatly produced a stimulant effect and a very mild "Trippy" feeling that lasted about 2 hours. It was not uncomfortable and allowed Bob to still function normally.

By the end of the 2nd week, Bob was sleeping through the night with absolutely NO withdraw feelings waking him up. The Oxy was also slightly more potent. He also noticed that rather than having to take a morning dose of oxy, he could wait until around 2-3:00 in the afternoon before even the slightest feeling of withdraw would begin. This was amazing considering just 2 weeks earlier, Bob couldn't go more than 8-10 hours without having terrible withdraws. He was now able to go 17-20 hours before even the slightest withdraws started.

Week 3:
This week, Bob decided to take a larger dose of Ibogaine for 2 days in a row. He had off work on Monday and Tuesday so decided to take advantage of it.

Bob woke up on Monday and took 250 mgs of Ibogaine HCL with his normal 5 mg Memantine. This caused a bit more of a Trippy feeling that lasted about 3-5 hours. It wasn't uncomfortable, just not something you should drive on at this dose. Memantine at 5 mgs was taken as usual that evening.

Tuesday Bob followed the same protocol as Monday.

By Wednesday, Bobs brain felt completely reset. The cravings for opiates were gone. He took 30 mgs of oxy Wednesday but just for fun...not out of a feeling of needing it or physical dependency.

Thursday, Bob continued to take Ibogaine but at a much lower dose...just 20 mgs first thing in the morning. He also took NO OPIATES AT ALL on this day. This is the first time in almost 2 years Bob as taken no opiate of any kind. He noticed slight chills that night but was able to fall back asleep with no real problem. He stopped all opiates for another 3 days just to be sure the the physical dependency was gone. I'm pleased to say it was. He had a fairly sever headache on day 2 but that was quickly remedied with 2 Excedrine Migraine pills.

Bob continued to take 20-50 mgs of Ibogaine and 5-10 mgs of Memantine for the next 2 weeks. He took an average of 1, 30mg oxycodone pill every other day. Each time was at a dose of 30 mgs of oxy. This was again, just for fun and not out of a feeling of physical dependancy. I know you maybe asking why not just quit completely. According to Bob, he likes the ability to relax with an occasional opiate as opposed to a beer like most of us. Whether that's a good idea or not, at least it doesn't control his life anymore and he isn't physically dependent on opiates to function...each to his/her own I guess.

The strange thing was that while Bob's physical dependency for opiates was almost completely gone, he still required 30 mgs of oxycodone to get any kind of a high. One would expect tolerance to go down, requiring less oxy to get a buzz or get high. This was not the case with Bob but everyone is different.

In conclusion, it seems that their may be a way to completely avoid the horror of opiate withdraw, even with a fairly high tolerance and addiction. Everyone says that there's no magic bullet to cure withdraws...but after reading and seeing Bobs experience first hand, I would have to disagree. In just 5 weeks Bob went from a 2 year, 180 mg plus per day oxycodone addiction, down to absolutely no physical dependence at all. He did this with NO withdraws and even continued to take the occasional oxy for fun when we wanted.

Warning and Disclaimer:
It would be irresponsible of me to suggest that this method of over coming opiate withdraw is for everyone. It's not. Before considering it, you must do your own research about the side effects of both Ibogaine and Memantine. Ibogaine should not be used by anyone with a pre-existing liver or heart problem. It should also not be taken in the evening as it is a stimulant. A thorough search of drug interactions, specifically with Memantine should also be done. Neither Bob nor myself are doctors so this information should be used for recreational reasons only and NOT taken as medical advice.

I'd be happy to answer any questions as best I can. But to all those who are trapped in the hell of opiate addiction, there is hope. It's not cheap but it's certainly cheaper than a daily opiate addiction and much cheaper than any Suboxone treatment clinic.

I truly hope this helps someone. I saw it change my friend Bob's life first hand. I also believe it can be accomplished in less time than what it took Bob. If your motivated, I think one could over come opiate addiction with little to no withdraws in as little as 3 weeks.

If your willing to put yourself through a full "Flood Dose" of Ibogaine, one could even avoid opiate withdraw and overcome their physical addiction in 24-36 hours. This would not be what i would recomend however as the Flood Dose Trip can be VERY intense and possibly very dangerous. Unless you are in perfect medical condition AND have a care giver/babysitter to stay with you for the entire trip, I would strongly advise against it. I beleive the low dose treatment option over a period of 2-5 weeks is the best and safest method to take.

It also must be noted that while Ibogaine and Memantine will get you through the physical addiction and withdraws fairly painlessly, the mental addiction will still be there. That said, it's very important to follow up with a support group of some kind...NA and/or AA meetings are very helpful and increase your chances of success in the long run greatly!
Having been through my own addictions and seen many others ruin their lives because of addiction, I understand the hell and shame of a downward spiral substance abuse can lead to. So when I find a method that works as well as the Low Dose Ibogaine/Memantine method, I get excited because I know it can change lives and heal those that are willing to be helped. Being a slave to a substance is no way to live and an easy way to die.

To all those that are struggling with opiate addiction...I'm here to tell you there's hope and a way to minimize if not completely eliminate the horrible opiate withdraws. All you need to do is decide to take that leap of faith! ;-)
 
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Btw...I realize I don't post much here but I have been reading and getting info from BL for years. Having gone through my own addiction issues and experienced the absolute hell of opiate withdraw on 3 separate occasions, (all were legally prescribed meds that I decided to quit on my own due to my inability to function at work while on pain meds) I have a great deal of compassion for anyone dealing with opiate addiction/withdraw.

There is no reason for anyone to go through the sleepless nights, vomiting, diarrhea and skin crawling joint pain of opiate withdraws ever again to get clean. There really is an alternative and I can't believe that in this country no one is using Ibogaine to get opiate addicts clean. It works and, while it isn't cheap, it's a hell of a lot cheaper than an opiate addiction. Not to mention it completely resets your brain and gives you back your motivation, and love for life again. Alright...I'm getting off my soap box...
 
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Very good report, interesting read and glad to hear this worked out so well for you :)
 
Very good report, interesting read and glad to hear this worked out so well for you :)
Thanks OTGee.

Has anyone else had any experience with Ibogaine and/or Memantine? I'd love to hear feedback from others. As common as opiate withdraw is now days, I'm really surprised at the lack of information that's out there.
 
Treshold doses of ibogaine is the next thing ill collect info on after my nmda antagonist thread; was away for awhile figuring out how to fix my predromal shizo.
 
Thresh hold dose of Ibogaine? What would be your goal with Ibogaine? Tolerance reduction? Beating addiction? Ibogaine has so many uses buy the one that stands out to me is it's ability to eliminate the horror of opiate withdrawal. I've seen to many friends and relatives ruin their lives with their addiction. Ibogaine is the first, real substance that has proven to be successfully at resetting your brain chemistry and allowing one to pick up the peices of there lives again. IMHO, it's nothing short of a mirical got breaking the chains of opiate addiction.
 
was away for awhile figuring out how to fix my predromal shizo.

"a prodromal period cannot be confirmed unless the emergence of the condition has occurred" seems the prevailing sentiment on schizophrenia. Not to say I know better than you, but I've seen you mention this on another thread and it struck me as quite odd. (If its a joke, it's quite funny. No insult here intended if not, however)
 
"a prodromal period cannot be confirmed unless the emergence of the condition has occurred" seems the prevailing sentiment on schizophrenia. Not to say I know better than you, but I've seen you mention this on another thread and it struck me as quite odd. (If its a joke, it's quite funny. No insult here intended if not, however)
It cant be confirmed but i did have strikingly simular negative symptions; strikingly simular cognitive decline that occurs over years; and after following a intervention based on shizophrenia i cured my symptions and i lack some cognitive shizo deficits wich ive had my whole life now.

I could have waited till i was shizo too to get a diagnosis; but i tought hmm nahh... take in mind it took me ages to get convinced i was but my paradoxal immunity to opiates and benzo's and psychosis coming easier and easier on stims someone came up to me and said; hey maybe we have this; i tought bullshit till it seemed like things that help shizo were helping me.
 
It cant be confirmed but i did have strikingly simular negative symptions; strikingly simular cognitive decline that occurs over years; and after following a intervention based on shizophrenia i cured my symptions and i lack some cognitive shizo deficits wich ive had my whole life now.

I could have waited till i was shizo too to get a diagnosis; but i tought hmm nahh... take in mind it took me ages to get convinced i was but my paradoxal immunity to opiates and benzo's and psychosis coming easier and easier on stims someone came up to me and said; hey maybe we have this; i tought bullshit till it seemed like things that help shizo were helping me.

Interesting. It makes sense too considering that the less the severity of psychosis, the greater the chance of remission.
 
Due to the fact that schizophrenia seems strongly connected with a glutamatergic hypofunction, as well as likely an excess in DAergic neurotransmission memantine may possibly be contraindicated in schizophrenia. Certainly I expect most NMDA antagonists to make things worse. And conversely, I have a feeling that perhaps one or other of the 'racetams, such as aniracetam may make an effective treatment, likewise AMPAkines. Schizophrenia seems tied in with an abnormal stress response during childhood and squirrely glucocorticoid release damaging the forming architecture of the brain, and the fact that the age of onset statistics seem to form a bell curve, at the maximal level during late childhood to early-mid adulthood seems to support this.

I wonder also, if positive modulators/glycine site agonists may also make an interesting potential approach to schizophrenia treatment. The aim being to correct the glutamatergic hypofunction. The NMDA receptor seems to act as a coincidence-detection circuit, and abnormal functioning of this might just tie in with the delusional aspects of schizophrenia.
I would, if schizophrenic, steer well clear of NMDA antagonists, including memantine.

Methoxetamine&low dose ibogaine might be an interesting avenue of exploration in combating opioid dependency, as MXE seems to substitute for opioids well.
My doc screwed up my oxy script just recently, and I've been using IV methoxetamine, a small hit with every dose of oxy to reduce tolerance, while tapering the oxy temporarily, as well as a bigger hit when needs be, to prevent withdrawal, reduce tolerance, and generally feel less shitty. With benzodiazepines and or chlormethiazole as needed. Pregabalin also seems effective at ameliorating withdrawal symptoms, although large doses (1-1.5g two to three times daily)

Tizanidine or clonidine will help with sleep, and by preventing the sympathetic nervous system from causing massive release of catecholamines, really improves the situation. Plugged tizanidine is much more potent than per os, and will effectively knock one out if sleep just will not come.
 
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Due to the fact that schizophrenia seems strongly connected with a glutamatergic hypofunction, as well as likely an excess in DAergic neurotransmission memantine may possibly be contraindicated in schizophrenia.
Excitoxiticy is a real problem in shizophrenia; its dysregulation but mainly hypoactivity.

There's an excess in tonic dopamine levels; but a defiency in phasic levels wich cause negative symptions; wich makes amphetamine prettymuch the cure for all negatives; it has to be combined with (a pdoc would say ap) a gabaergic tough to reduce the excessive tonic levels and prevent stimulant induced positive symptions.

And conversely, I have a feeling that perhaps one or other of the 'racetams, such as aniracetam may make an effective treatment, likewise AMPAkines.
When i go semi psychotic on amp alone; nefiracetam COMPLETELY reverses any psychotic or paranoia like symption.

Glycine agonists just allow glutamate to activate nmda;they should be combined with a nmda agonist; l glutamine on its own allready did wonders for me. Memantine is more of a modulator wich doesnt interfere with normal glutaminergic transmission only with excessive; it certainly wont interfere with hypoactive transmission and indeed it has been shown to improve shizophrenia.
 
Glutamate is the key for everything; alot more then you will imagine but i will only slowly reveal the potentials; just my first discovery tolerance prevention with memantine (atleast some ppl did it before me but i tought it would be far more effective then ppl tought wich is why it was talked about but ppl remain skeptical) showed what modulating glutamate is capable off.
 
An NMDA agonist would be HORRIBLY excitotoxic. Look at ibotenic acid, its used to selectively lesion areas of the brain in rats.
A positive modulator would be interesting, such as maybe D-cycloserine.
 
An NMDA agonist would be HORRIBLY excitotoxic. Look at ibotenic acid, its used to selectively lesion areas of the brain in rats.
A positive modulator would be interesting, such as maybe D-cycloserine.

Glycine site partial agonists are being investigated for this purpose, among others.
 
Yes, I think I'd heard about that. Will be interesting to see how they perform, or if any make it to market.
 
i just found this thread, as i have recently gotten a gram of ibogaine hcl and am awaiting another 2 grams of TA so i can administer a flood dose. i got 1 gram hcl 4 days ago, and 3 days ago began on 25mg, and tkaing my normal opiate dose (80mg powder heroin) a few hours later, but doing half (40mg) and not feeling any real relief from wd, took the other half (40mg again) about 30 mins later. (IV) the second day i took 28 mg ibogaine hcl and took 50mg IV heroin and felt sleepy, so took a nap about noon yesterday. now today, day 3, i took 32mg of ibogaine about noon also, but having started feeling wd when i first woke up, about 9 am, but EXTREMELY MILD for what i would normally be going through, i took 40mg heroin followed by another 10mg about 10 mins later. felt relief and took my 32mg ibogaine hcl at noon. i will try to not take any more opiates today, as i forgot to mention, i was on about 160mg very potent powder white china heroin a day, 80 mg every 12 hours or so. low dose ibogaine has def allowed me to cut my opiate intake down by about half, and in just 3 days. i will be posting next weeks experiance with a full 1700mg flood dose. 1000mg hcl and 700 mg TA. sorry for posting this on here since this thread wenbt from ibogaine to schizo, but i felt it was the best place for me to poost this comment. i had a question for anyone who has taken ibogaine in low dose, its uppossed to be a mild stimulant at such low dose, but as soon as i have taken 28mg yesterday then 32 mg today, i felt VERY sleepy and took approx an hour-2 hour nap about 45 mins after taking low dose ibogaine. does anyone know if this mean when i take my tester dose of 200 mg before the rest of my flood dose i will be allergic and will ahve negative afffects or am i just worrying myself for nothing? and i see the benefit of taking memantine, but will not be taking any of that. just taper with low dose iboga till flood dose then hopefully only a booster iboga dose once in a while many months later. good luck to everyone using ibogaine to get clean, or just to lower daily intake of opiates if still needed for pain management. be safe and good luck!
 
An NMDA agonist would be HORRIBLY excitotoxic. Look at ibotenic acid, its used to selectively lesion areas of the brain in rats.
A positive modulator would be interesting, such as maybe D-cycloserine.
Agonizing the glysine site doesnt do much; its a matter of taking it easy (yup easier said then done.)
 
i just found this thread, as i have recently gotten a gram of ibogaine hcl and am awaiting another 2 grams of TA so i can administer a flood dose. i got 1 gram hcl 4 days ago, and 3 days ago began on 25mg, and tkaing my normal opiate dose (80mg powder heroin) a few hours later, but doing half (40mg) and not feeling any real relief from wd, took the other half (40mg again) about 30 mins later. (IV) the second day i took 28 mg ibogaine hcl and took 50mg IV heroin and felt sleepy, so took a nap about noon yesterday. now today, day 3, i took 32mg of ibogaine about noon also, but having started feeling wd when i first woke up, about 9 am, but EXTREMELY MILD for what i would normally be going through, i took 40mg heroin followed by another 10mg about 10 mins later. felt relief and took my 32mg ibogaine hcl at noon. i will try to not take any more opiates today, as i forgot to mention, i was on about 160mg very potent powder white china heroin a day, 80 mg every 12 hours or so. low dose ibogaine has def allowed me to cut my opiate intake down by about half, and in just 3 days. i will be posting next weeks experiance with a full 1700mg flood dose. 1000mg hcl and 700 mg TA. sorry for posting this on here since this thread wenbt from ibogaine to schizo, but i felt it was the best place for me to poost this comment. i had a question for anyone who has taken ibogaine in low dose, its uppossed to be a mild stimulant at such low dose, but as soon as i have taken 28mg yesterday then 32 mg today, i felt VERY sleepy and took approx an hour-2 hour nap about 45 mins after taking low dose ibogaine. does anyone know if this mean when i take my tester dose of 200 mg before the rest of my flood dose i will be allergic and will ahve negative afffects or am i just worrying myself for nothing? and i see the benefit of taking memantine, but will not be taking any of that. just taper with low dose iboga till flood dose then hopefully only a booster iboga dose once in a while many months later. good luck to everyone using ibogaine to get clean, or just to lower daily intake of opiates if still needed for pain management. be safe and good luck!
Please keep us updated on your flood dose results. I'll be very interested to see how it turns out. I wish you the best!
 
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