Drug is the only reason I do drugs, so I tried a lot of things.
According to my experience, here is my list:
1. LSD is by far the best musical enhancer. Richness, details and separation are excellent, concentration is easy, emotions are profound. I particularly like the physical and visceral perception of the bass. The perception and the visualisation of the musical landscape are beautiful. The long lasting effect is nice if you have the time. I had several musical long lasting orgasms on LSD.
2. Mushrooms are close to LSD (regarding music), but concentration and control of the mind are less easy. The short duration is a bit frustrating. Hallucinations can be more present. Afterglow is better than lsd tho.
3. MDMA is very good for music. It particularly increases the perception of the details. The highs are clearer.
4. Cannabis. The easiest and cheapest way to enhance the perception of the music. Better separation, deeper emotions, relaxing effect, ....
I also tried several others things (amt, 2cd, coke, methylone, mcpp, ...). Some slightly increased the perception but not at the same level. Moreover I didn't like the nasty the side effects. I don't even talk about alcohol 8)
In order to even more increase the perception of the music, combination can be your friend. So here my best way to musical nirvana:
1. LSD+MDMA+Cannabis. If you can handle it and you have a very good audio system, you will probably fall in love with the music. I had each time a musical orgasm on this. The interesting side is that the increased perception of the bass on LSD is well balanced with the increased perception of highs on MDMA.
2. Mushrooms+MDMA+Cannabis. Little brother of the 1. Mushrooms/cannabis combination can be more tricky but MDMA seems to partially solves the problem.
If someone knows a substance or combination more interesting musically, I'm interested
About the type of music, I'd like to add that I can listen to any type of music on any of the substance I was talking about. I know that each drug is culturally related to certain types of music but the openness the substance brings can easily let you transgress these silly frontiers.