Lorne???
Bluelight Crew
- Joined
- May 3, 2014
- Messages
- 2,558
I think you mean it contains SNRI properties (it is not SSRI inhibiting, it is a reuptake inhibitor of serotonin and norepinephrine) how strong it inhibits the reuptake of serotonin would translate to how likely it is to cause serotonin syndrome. Every doctor should know this, why it would ever be used first over proven safe and natural opiates like morphine - the gold standard, I just don't understand. I know the serotonin has something to do with migraines as migraines are treated with triptans which are serotonin agonists, and people with cluster headaches (the worst crazy most fucked up migraine) have taken low doses of 5htp agonist psychedelics as a form of treatment. The risk of serotonin syndrome Vs. just giving morphine seems like a no brainer. May tramadol is a specific opioid good for migraines?
All very interesting, but headaches are still very poorly understood, some basic stuff is known, but the true cause of all headaches and solutions seems to elude us. I wonder how long the brain will hold onto it's mysteries.
When it comes to pharmacology, most doctors don't know shit. I have always hated fucking pethidine, yet a small portion of doctors still use it religiously, despite it being one of the weakest, most unreliable opioids around, with the worst potential for side effects.
Yeah, giving pethidine when you have access to morphine and dozens of other effective safe opioids without atypical side effects is stupid. Giving it to someone on tramadol should be grounds to lose your fuckibg prescription pad.