Varying quality is an issue, having tried many different batches/vendors/polymorphisms. The very high purity (99%+) batches are a world of difference from the lower quality mxe that is unfortunately also going around and giving it a bad name. for this I wish it becomes approved/regulated/standardized because the quality stuff is nothing short of a game-changer for the drug world. I say treat every alcoholic, opiate addict, speed freak and crack head with a structured mxe therapy regimen and the world would be a much better place.
I propose that it's not purity but the form that's the problem.
there are atleast 3 types of mxe- freebase, citrate and hcl.
we can tell by these alone that the freebase would be roughly 2x the molar density of the citrate (only marginally different from hcl to freebase) so, roughly 2x the 'bioeffectiveness'. also, the citrate version seems to vape into something that is neither citric acid or PCE. that being said,
lil math: hope the mxe doesn't fuck with it.
210.14 is the molar mass of citric acid, 36 is the mass of hcl
247.33 is the molar mass of freebase mxe
presuming there's also a sulphate which is what causes the burnt throats. easy to find, easy to use in china.
(I'm not a chemist, which is a serious problem for me. there is a chance that 2 mxe molecules can bind to 1 citric acid which would make it similar to the molar weight of the sulphate)
a smart lab would start to convert the product to citrate as it would give a higher yeild while still being technically pure.
a chinese lab would use sulphuric acid which would be much more likely to burn your throat.
there is also anecdotal evidence that the citrate isn't considerably stable compared to the freebase or the sulphate or hcl due to it's multiplicitive bindings.
there are problems tho, cause mxe doesn't seem to exhibit wildly different hydrophobia in any form which is why you shouldn't use a waterbong to smoke it tho some type of concetrating chamber does seem to help (ie salvia?)
aside from direct vapepoint testing, there isn't very much a hoby rc enthusiast can do to determine what version they have.
when my next batch arrives (today? :O ) I'm going to try to freebase atleast a portion of it using baking soda...
I've also found that an empty- tho huge- waterbong is the perfect aparatus for this.
pack a small bowl, and smoke it, add a drop of Vetetable Glycerin to the ash then put your mxe on that. seems to help with the vapepoint, or atleast as a way of heat distribution.
before the vg I've also created a small bowl filled with glass shards about 3mm long and 1mm wide that I've melted 'off' batches of mxe onto, heating this from the bottom like a lightbulb vape seems to help a great portion... you have to put tenth a gram in the bowl and hope you get your heating right tho, or you're in for a wild ride.
I have a ton of experience with mxe and I'm going to learn more today.
with the gram I get, I'll try to freebase a portion, and salt a portion with hcl and citrate... I'll figure this out yet.
What I do is this:
Weight out about 15mg on my micro scale.
Take about 4-5 drops of water into a miniature metal cup. Mix it with plunger of syringe until the crystals have dissolved.
Pour the solution into my oral syringe, apply some baby oil to the syringe
I only seem to go about an inch deep, not to get explicit but I really can't push any farther, and if I did it kinda hurts....gross
Then I inject and usually sit on my sit for a couple minutes to make sure.
I think I may not be going deep enough, but it goes in and stays there, so it's gotta be getting absorbed somewhere no?
instead of water try propelene glycol, Vegetable glyceryn or DMSO. These will help the bioavail.