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The Big & Dandy Methoxetamine / MXE Thread - Part 16 - Sweet 16 mind-control machine

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DoeJohn said:
dont take mxe with any seratonin kind of drugs
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Speaking of this, I noticed that TripSit's drug combo chart used to list MXE + SSRIs as "Safe, slight increase" but now lists it with a purple "Serotonin syndrome" warning.

What do you guys think about the risks of this combo? I have a friend I like to take MXE with, but he is currently prescribed an SSRI, so ive limited our doses to no more than 40mg in a night.
 
Based entirely on my personal experiences, as well as the fact MXE's effects seem to vary so ridiculously from person to person and batch to batch....who fucking knows whether it's safe or not. Who even knows if what they just railed was even MXE to begin with.

My experience (all taken orally on a 100% empty stomach):
T+0:00 - 20mg MXE
T+0:45 - 150mg MDMA
T+1:45 - 20mg MXE
T+2:15 - 90mg MDMA

Was my roll intensified? Absolutely not. If anything, it was dulled. But not even in a good way - it's like the combination served to destroy all desired effects from either drug. No tipsy feelings from the MXE, and barely any euphoria or stimulation from the MDMA. I actually felt quite sober for the most part. My MDMA is "pure" tested crystal, and I've had the same batch since the beginning of LAST year. This exact baggy of MXE has also been consumed by a fellow BLer, combined with MDxx, in LOWER dosages than mine (for the MDMA at least), with significantly better and more synergistic results. The kind of results you'd expect mixing a potential SRI with a releaser.

Take from this what you will....obviously it's ALWAYS best to err on the side of caution rather than use the above as any kind of evidence as to the 'safety' of mixing these compounds.....not like the above would really motivate you to bother trying it yourself anyway haha
 
trozzle said:
Based entirely on my personal experiences, as well as the fact MXE's effects seem to vary so ridiculously from person to person and batch to batch....who fucking knows whether it's safe or not. Who even knows if what they just railed was even MXE to begin with.

My experience (all taken orally on a 100% empty stomach):
T+0:00 - 20mg MXE
T+0:45 - 150mg MDMA
T+1:45 - 20mg MXE
T+2:15 - 90mg MDMA

Was my roll intensified? Absolutely not. If anything, it was dulled. But not even in a good way - it's like the combination served to destroy all desired effects from either drug. No tipsy feelings from the MXE, and barely any euphoria or stimulation from the MDMA. I actually felt quite sober for the most part. My MDMA is "pure" tested crystal, and I've had the same batch since the beginning of LAST year. This exact baggy of MXE has also been consumed by a fellow BLer, combined with MDxx, in LOWER dosages than mine (for the MDMA at least), with significantly better and more synergistic results. The kind of results you'd expect mixing a potential SRI with a releaser.

Take from this what you will....obviously it's ALWAYS best to err on the side of caution rather than use the above as any kind of evidence as to the 'safety' of mixing these compounds.....not like the above would really motivate you to bother trying it yourself anyway haha
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it's b/c you didn't put it in ur bum matey ;-)
 
hahahahaha hey, if I knew it would make THAT kind of difference, I'd be all for it :P alas, I'd expect nothing more than more intense effects....though can you really intensify sweet fuck all? :(
 
I've combined MXE with 6-APB, 4-FA and MDMA and never experienced anything that pointed towards serotonin syndrome. We don't exactly know how MXE works on the brain and it's hard to say for certain what is safe and what is not. It seems the risk of mixing it with serotonergic drugs are somewhat overstated though. If it feels fine with serotonin releasers I'd find it hard to imagine it wouldn't be fine to mix it with SSRIs. Releasing agents pump out more serotonin into the synaptic cleft than reuptake inhibitors do.

If you want to play it safe, start with very small doses (5-10mg) and leave enough time between redoses. See how you feel at each stage, MXE is very redosable as effects just simple stack up. It's not one of those drugs where taking a high initial dose is required!
 
Personally I'll be trialling a 20mg oral dose again prior to my next roll, however I'll be taking my normal MDMA dose rather than the reduced dose above. Shall see how that goes :)
 
murphythecat said:
amazing indeed. quite something and I cant wait to explore, but not for everyone. Ill also make a lot of try outs with mxe and tryptamine. there seem to be a synergy

how safe is MXE for the health? any weird side effects you guys noticed?
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I feel fantastic. My health seems to be tuned well even though I've been using MXE basically to the point of daily as an antidepressant. It matters what you do on MXE. I'm still buzzing from the yoga I did earlier with my friend, we share a very close connection so it is always invigorating to our spirits when we connect. Just keep up with good flow and handling of the energy and there seems to be little risk of danger/toxicity.
 
vortech said:
I feel fantastic. My health seems to be tuned well even though I've been using MXE basically to the point of daily as an antidepressant. It matters what you do on MXE. I'm still buzzing from the yoga I did earlier with my friend, we share a very close connection so it is always invigorating to our spirits when we connect. Just keep up with good flow and handling of the energy and there seems to be little risk of danger/toxicity.
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Yo vortech, you seem like a well versed mxe aficianado.

I have a concern, I've been looking for an answer for about 8 months now, can't figure it out with google.

About 8 months ago I started becoming very receptive to MXE. Like it did wonders for me and every aspect of my being.

I may have liked it too much and ended up using it for like 3 weeks straight...low doses throughout the day, always slept and ate well, however the doses were like dawn to dusk with maybe 1 or 2 days off per week during those 21 days. The last day I took my morning dose, perhaps 20mg oral, I felt a sensation, almost an agitation if you will, in the left side of my head, like probably my brain, it felt awkward in a small spot, localized area, on the left side of my head.

What caused this? (Only a very good neurologist could probably say for sure) Anytime I redose MXE after taking a single dose, the last few times I paid my respects (months ago) I swear I feel an agitation (not painful, more like a distinct pressure in a small area) in the left side of the top of my head.

Thoughts? Should I acquire some mxe, dose once or twice, and provide a live update of the situation?
 
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Like around your left temple? I know I've had similar feelings while on serotonergic drugs where it throbbed in that area.
My guess is it's completely nothing, but if it concerns you that much then don't use MXE again.
 
it could be anything. Agitation in the left side of the head is too vague a symptom... test could be run with proper equipment, but even then, it could have been a temporal unrelated and invisible mulfunction

i too have abused mxe without too many bad side effects. but now that i am not abusing it anymore, i got the feeling i shouldn't have done it
i don't think the best use of mxe is to take daily, as it loses its magic, even though you don't realise it while taking it everyday. the effects change to worse, even if the person taking it doesnt seem to notice such change

i found out a better drug for depression is mucuna pruriens. Also iboga microdoses

...but i'm repeating myself like a senile old granpa talking about the war...
 
cosmic._.ape said:
it could be anything. Agitation in the left side of the head is too vague a symptom... test could be run with proper equipment, but even then, it could have been a temporal unrelated and invisible mulfunction

i too have abused mxe without too many bad side effects. but now that i am not abusing it anymore, i got the feeling i shouldn't have done it
i don't think the best use of mxe is to take daily, as it loses its magic, even though you don't realise it while taking it everyday. the effects change to worse, even if the person taking it doesnt seem to notice such change

i found out a better drug for depression is mucuna pruriens. Also iboga microdoses

...but i'm repeating myself like a senile old granpa talking about the war...
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You are correct cosmic ape. I'm not setting the best example by saying its OK to use daily, because in truth the ride always has to come to an end, or at least a temporary reservicing, to let the receptors chill out for awhile. I'm on my last day of daily use for....at least a week I hope. But, if it does come to the point where you find yourself dosing daily, 'check yourself before you wreck yourself!'.

Lestat.Hypersphere, as for the tension in your head, I have experienced the same thing after daily dosing for more than a week at a time. I chalk it up to buildup of metabolites as the cause, but that's just my guess.
 
Thanks. I must have been dosing way too frequently now that I think about it. I was only dosing anywhere from 5 to 25mg at a time, but I didn't keep track of how many times I would dose per day.

The metabolites were surely piling up in my system, leaving a surplus in my brain.

Boy oh boy does mxe help me resolve personal issues, I could really use some for some emotional and life rectifying work. Probably going to get some next Friday when I get paid again. Biweekly paychecks (one day I will be salaried or getting paid daily for my own business) and credit card debt sucks.

Probably a half dozen to a full dozen doses on some days, too frequent.

Should definitely keep track and dose much less frequently next time. Maybe up the first dose and quit doing so many small doses.

I find the most benefit at subhole doses.

Anyways I would never want to hole on mxe. I've been out of body on ketamine before, actually it wasn't self administered, I had broken my arm in half, like it was bent and floppy in my forearm because both bones snapped clean through (thanks porn and early semen loss through masturbation as a young adolescent, energy loss weakened my bones, look to Ayurveda for a scientific explanation) anyways when they set it in the hospital they administered ketamine as they wanted me awake but not present mentally for the bone setting, fucking beyond imaginable pain however I was completely out of my body, floating on the ceiling watching the doctors around my body.

Anyways ya I don't really like heavy doses of dissociatives. I like how moderate doses tend to have a 'reassociative' aspect to them.

DXM is a whole nother animal if you ask me.

K and MXE do wonders for me, they are almost like medicine or spiritual allies in a shamanistic sense. The are healing tools yet also offer much in terms of recreation and enjoyment.

DXM (I've taken it dozens of times from small to large sized doses.) is very strange. Alien. I do not enjoy it. Yet it offers lessons all the same at the higher plateaus. Lower plateau sailing for me is choppy, tedious, dysphoric, and makes me feel like the Tin Man without any grease. MXE take me to a different dimension even with low doses, a place of infinite possibilites, with improved physical coordination (DXM turns me into an demigod physically, physical strength and endurance increases tenfold) and wonderous mental and spiritual enhancement.
 
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40 mg mxe oral, 15mg 2ce and 15 mg 4 aco det is enough for breakthrough my friend told me. he was in alex grey paintings.
 
vortech said:
I feel fantastic. My health seems to be tuned well even though I've been using MXE basically to the point of daily as an antidepressant
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I agree. I used to use MXE as an anti-depressant myself. At small doses, that is. Large doses are counter productive in every day use, for obvious reasons. ;)




I have personally grown to enjoy Methoxetamine more than Ketamine and Dextromethorphan, my two prior favorite dissociative class hallucinogens.

I believe this is due to its long duration, and 'clean' feeling.

I love M-Holes because they last long enough for you to fully grasp them, as opposed to sometimes blacking out throughout the entire duration of K-Hole, for example.
 
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Cosmic Giraffe said:
Are they actualy in the process of banning it? What a shame. The benefits this medicine provides are infinite.
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I'm not entirely sure.
From what I'm aware of it is currently only illegal in two-four U.S. States.
It isn't Federally Scheduled, however I believe it can fall under the Analog Act for PCP?
Any thoughts on this?
 
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