• Psychedelic Drugs Welcome Guest
    View threads about
    Posting RulesBluelight Rules
    PD's Best Threads Index
    Social ThreadSupport Bluelight
    Psychedelic Beginner's FAQ
  • PD Moderators: Esperighanto | JackARoe |

☛ Official ☚ The Big & Dandy HBWR/MGS/LSA Thread - Part 3: Fluffy Dreams Continued

Reported by a member. Just thought since we are letting all thoughts in I would post this one. Lots of refuting in this thread. But that is what research is for.

"LSI is not a psychedelic drug. It's a physiologically unstable schiff base. It could be converted to a secondary amine via reductive amination, but that would no longer be LSI. The secondary amine could be psychedelic or physiologically stable, but that hasn't been studied."
 
"Ergine is classified as a depressant federally. Erginine isn't classified at all. It is definitely stimulating, but I have not taken above 1 mg. 7 seeds (a. nervosa) were smashed and added to orange cool-aid. The mixture was frozen, thawed and then 1 teaspoon of baking soda was added. 0 nausea and mild vasoconstriction consistent with an ergine dominant preparation."
 
"I'm still convinced ashes are key. Even if freezing is less traditional, it's still natural."
 
donotdothis said:
Explaining decrease of vasoconstriction with the newest methods:

"Isoergine and ergine are relatively small, highly lipophilic molecules. Ergobalansine (and its epimer ergobalansinine) are significantly larger, preventing them from efficiently penetrating within a short timeframe."
Click to expand...

I had to heavily edit this post but it should be perfect. It originally had ergobasine.

pubchem.ncbi.nlm.nih.gov

Ergometrine

Ergometrine | C19H23N3O2 | CID 443884 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
pubchem.ncbi.nlm.nih.gov pubchem.ncbi.nlm.nih.gov
pubchem.ncbi.nlm.nih.gov

Ergobalansine

Ergobalansine | C28H35N5O5 | CID 14753572 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
pubchem.ncbi.nlm.nih.gov pubchem.ncbi.nlm.nih.gov
 
JackARoe said:
Reported by a member. Just thought since we are letting all thoughts in I would post this one. Lots of refuting in this thread. But that is what research is for.

"LSI is not a psychedelic drug. It's a physiologically unstable schiff base. It could be converted to a secondary amine via reductive amination, but that would no longer be LSI. The secondary amine could be psychedelic or physiologically stable, but that hasn't been studied."
Click to expand...

I'd clarify that quote by stating that LSI refers to a condensation product formed between (at least) LSA and isovaleraldehyde (3-methylbutanal). Claiming that it's not psychoactive seems hasty. Understandable of course, but hasty still. The name LSiV seems more appropriate.
 
The psychoactivity of LSI isn’t what is under debate. Adduct formation in an aqueous environment just isn’t going to happen.


A member even tried to make it based on instructions posted en masse in that one thread, and ran TLC plates that showed no chemical change between the seed extract and the one treated with aldehyde.
 
Allylbenzene said:
Indeed, of this I'm aware.


The same criticism is levelled at all the adduct formations, eg performed using a tincture of cinnamon & cumin (reported by user flickedbic) or sassafras bark (reported by user lysurgeon).
Click to expand...
Well that makes sense. There has been no evidence that aldehydes can form stable adducts in >99% aqueous solutions, and there is evidence that this doesn’t occur.
 
Skorpio said:
There has been no evidence that aldehydes can form stable adducts in >99% aqueous solutions, and there is evidence that this doesn’t occur.
Click to expand...

All I can reasonably deduce from the reports is that anhydrous conditions aren't imperative for this LSA/aldehyde "rxn" to occur.
 
"This has been my first time ever trying a psychedelic and I’m tripping rn i originally took 6 and threw up after 30 minutes before I felt effects, I then resided with 2 seeds sublingually and like probably 8 wfter to get the effects I want, I am trying hard to type this, listening to seek and destroy, I feel at one with everything."

 
I was suggested an alternative technique for experimenting with higher doses where isomerization is not enough:

"If you start venturing into 20 seeds or more at once, you will want to destroy the ergonovine entirely. As the favored epimer, roughly 60% will still be active. This is where a stronger base and limited headspace is actually ideal. Shaking the mixture regularly after your freeze-thaw cycle accomplishes this by introducing oxygen. Ergonovine is particularly prone to this combo moreso than lysergamide."

Ergometrinine - PMC

The absolute configuration of ergometrinine, C19H23N3O2 {systematic name: (6aR,9S)-N-[(S)-1-hydroxypropan-2-yl]-7-methyl-4,6,6a,7,8,9-hexahydroindolo[4,3-fg]quinoline-9-carboxamide}, was established based on epimerization reaction of ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
Last edited:
"The highly polar freebase ergometrine remains partially dissolved where it's rapidly destroyed by dissolved oxygen, whereas the non-polar freebase ergine (LSA) is hydrophobic and immediately crashes out of solution as a precipitate. This separation creates a protective shielding for the LSA, allowing the dissolved atmospheric oxygen to aggressively decompose the vulnerable, water-bound ergometrine while leaving the precipitated LSA structurally intact shortterm."
 
Last edited:
Applying the zapotec dose of 13 seeds to HBWR:

Weight~~~~~~~1.3g
Alkaloids (%)~~~0.3%-1.0%
Alkaloids (mg)~~3.9mg-13.0mg
Isoergine|Ergine~3.1mg-10.4mg
Other~~~~~~~~0.8mg-2.6 mg
 
Nobody is really talking about the leaves either. They might be 10x less potent but 0.1% is still more than the seeds of some other species. I am going to grow some indoors.

Identification and determination of ergot alkaloids in Morning Glory cultivars - PMC

Seeds of plants from Ipomoea genera contain numerous ergot alkaloids, including psychoactive ergine and ergometrine, and are often abused as so-called “legal highs.” In this work, an analytical method for determination of ergine and ergometrine, and ...
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
 
You must log in or register to reply here.
Top