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☛ Official ☚ The Big & Dandy Guide to Rectal Administration (Plugging)

^You'll need some pH papers, which you can get cheaply and easily online, or I believe there's certain retail outlets that sell them (perhaps pool supply shops?). Simply dissolve your drug in water then dip the edge of a pH strip in and match the color to the pH chart. A neutral pH is 7. I'm not sure what the range is around 7 that's not likely to burn, but if you need to raise the pH slowly add baking soda (you're unlikely to need more than 1/5th the weight of your drug in baking soda) and if you need to lower it slowly add white vinegar or citric acid from the canning section of the grocery store (again, just drops at a time, it won't take much). You will need to heat the baking soda/drug/water solution to get the baking soda to dissolve clearly into solution. I'm not sure if there are other chemical properties of commonly used compounds other than high or low pH that could cause tissue damaging chemical burns or not, but I'd think making solutions neutral should address most issues.
 
Phenol on the mucous membranes sounds awesome.
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Yeah, people complain about drugs being painful to plug, but I think a phenol suppository would be absolutely fucked.

though would a coca butter suppository require a larger dose of drug to deal with the slow and incomplete absorption ?
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No, because it's made of a small amount of easily melted oil, it will be fairly rapidly and completely absorbed because it will liquify and move across the mucous membranes fairly rapidly.
 
Yeah, people complain about drugs being painful to plug, but I think a phenol suppository would be absolutely fucked.
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I'm not sure I'm familiar with the the sense of "absolutely fucked" being used here. In low concentrations phenol is a harmless local anesthetic used in throat sprays and even in minor surgeries, right? Of course, I understand that just straight shoving phenol up one's ass would be quite fucked indeed, though that would presumably be true for any acid would it not? So what do you mean? I just recommended using phenol solution to dissolve butt irritating compounds above and now you have me concerned I've recommended something that will absolutely fuck some poor person's butt.

EDIT: Out of concern for the forum's welfare I've just plugged a small amount of phenol solution in the form of sore throat spray along with some MXE as a test and I feel just great. I was kind of hoping it would be more tingly but, oh well, just numb will have to do for now.
 
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^Huh, fair enough. It's never bothered me at the concentration found in sore throat sprays (neither my throat nor, now, my ass). It's not too often that it's called for while plugging though, so hopefully that won't be an issue for anyone, practically speaking.
 
sekio said:
Phenol is a pretty serious mucus membrane irritant, especially if used regularly.
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"Irritant" is putting it very mildly actually, it's corrosive. :D I guess in the concentrations used it isn't anything more than irritating, but concentrated Phenol is a hellishly nasty substance to have on your mucous membranes.
 
psood0nym said:
Strange that it's the active ingredient in convenience store sore throat spray if it's really all that bad.
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In extremely low concentration maybe, yeah. And surely not where I'm coming from either (Germany). That stuff eats through your tissue, in fact that's one of the things it's still used for (treatment of recurring ingrown toenails) and not as first line of treatment either.

Just because something is contained in an OTC medication does NOT mean it is healthy or even unproblematic in any way. E.g. we have an OTC throat spray that contains lidocaine and ethanol as the only ingredients. Sure, the stuff will make you feel better for an hour or two, but after that most throats will be swollen like crazy due to the 90% ethanol that has been applied to it. Everyone who has ever attempted to drink 190 proof knows ethanol is irritating to mucous membranes and sucks every last drop of water out of em.

Phenol IS very bad for your mucous membranes, there is no doubt about it. It is corrosive like I said. I'd advise anyone who attempts to make rectal suppositories at home to watch the dosage. Dosis sola facit venenum. Honestly though, I wouldn't recommend applying anything that contains phenol to your rectum on a regular basis.

The patent for the suppositories is from 1941 and I strongly doubt that phenol is still used for that purpose today (preservant for the coacoa butter and glycerin I'd assume).

On the plus side, I'm pretty sure it kills all bacteria and fungi at very low concentrations. That's why it's classically been used in histological preparations as a preservant. This is probably also why US (?) throat spray contains phenol, but I could be wrong.
 
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^As stated, I didn't notice any irritation from a single use, though it certainly sounds like using it regularly could cause problems. It's a weak acid, which is why it's corrosive, though to the best of my knowledge if an acid is diluted enough that its pH is within acceptable ranges it should pose no issue. I'd think benzocaine would be fine, however as crOOk stated some local anesthetics are dissolved in ethanol, which is an irritant. It'd be easy enough to simply boil off the ethanol though I'd think. There's nothing in its description that makes it sound corrosive at any concentration.
 
I tried plugging DMT dissolved in vinegar. Used the dose I'd use for an oral dose and within 2 minutes I was at the peak of the most powerful DMT trip I've ever had. About as much fun as being in a car crash. And it still makes you vomit anyway - which was the only reason I tried plugging it. I wouldn't bother pluggin DMT too often.
 
So, randomly came across some DMT today, and am planning on combining it in a syringe with MXE as those two are my favorite psychedelics. I just went over the entire thread and I still have a couple questions.
It's freebase, so I'm wondering what to dissolve it in. I have some Propylene Glycol, as that is an alcohol I imagine it would dissolve fairly well in it?
I see that both salts and freebase DMT can be plugged, but would one offer higher BA%?
 
Ralt said:
So, randomly came across some DMT today, and am planning on combining it in a syringe with MXE as those two are my favorite psychedelics. I just went over the entire thread and I still have a couple questions.
It's freebase, so I'm wondering what to dissolve it in. I have some Propylene Glycol, as that is an alcohol I imagine it would dissolve fairly well in it?
I see that both salts and freebase DMT can be plugged, but would one offer higher BA%?
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I think the DMT needs to be Hcl or fumarate, I've always read that plugging the freebase was rather painfull, to the degree were it ruins the trip. Dunno though, never tried myself, but yeah, pure freebase DMT on the tongue tastes rather caustic. You don't want that up your bumhole.
 
Fagott said:
I think the DMT needs to be Hcl or fumarate, I've always read that plugging the freebase was rather painfull, to the degree were it ruins the trip. Dunno though, never tried myself, but yeah, pure freebase DMT on the tongue tastes rather caustic. You don't want that up your bumhole.
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I'm not *that* worried about the burn, and would rather go with whatever causes the BA% to go up. I see a lot of people dissolving the freebase into milk in this thread, is it simply because the freebase is soluble in milk, or it reduces burn, or something in the milk salts the freebase or....?

Alternatively, what would be the best common household item to convert the freebase into a salt? The most ghetto I can think up on the top of my head would be to salt it with orange juice to form DMT citrate, but that seems *way* ghetto.
 
Ralt said:
So, randomly came across some DMT today, and am planning on combining it in a syringe with MXE as those two are my favorite psychedelics. I just went over the entire thread and I still have a couple questions.
It's freebase, so I'm wondering what to dissolve it in. I have some Propylene Glycol, as that is an alcohol I imagine it would dissolve fairly well in it?
I see that both salts and freebase DMT can be plugged, but would one offer higher BA%?
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Shit's gonna burn your ass!!! DMT freebase dissolves just fine in water.
 
crOOk said:
Shit's gonna burn your ass!!! DMT freebase dissolves just fine in water.
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Huh, why then are quite a few people in the thread saying they dissolve it in milk?

And what would you recommend for salting the freebase?
 
Ralt said:
Huh, why then are quite a few people in the thread saying they dissolve it in milk?

And what would you recommend for salting the freebase?
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How would I know?! My guess would be: Because it gets caught up in the micelles even better than in plain water. This doesn't mean it's in solution though. The DMT freebase I've had (and I've had a lot of DMT!!) was always soluble in water.
Regarding production of a salt: It's very hard to yield crystalline DMT salts afaik. I've never attempted it. As long as you keep it in solution though, you should be fine using acetic acid or hydrochloric acid, both of which should be readily available. Just calculate the amount you need or check the pH of the solution. Again, I've never played around with this and while being a huge fan of rectal administration of psychoactive drugs, I never felt this ROA would be a good choice for DMT. I can see how smoking is a bit inconvenient though. Maybe you should check how IV users prepare their shots and use the same method for your rectal shot. I don't even know if DMT would really burn that bad in your rectum. The burn I experience when putting DMT on my tongue might just be due to it's basic properties. The liquid in your rectum (yuk) can physiologically have a pH of around up to 10 if I'm not mistaken. It might not be all that bad. Then again, maybe DMT is just caustic and will burn either way lol.

Try it and tell us how it went! Btw I believe there are other forums which discuss this at length.
 
I recommend and caution the following: solution pH and solvent. It is possible to administer solvents other than water (e.g.: ppg) Consider though, though, that the nature of PPG is to attract water. A 100% PPG solution is not recommended as it will likely result in an enema, of sorts. Personally, I've found tolerable solutions to be in the 30% PPG 70% H20 range. Even creeping up to 50% can be doable, but uncomfortable. A simple oral syringe from the pharmacy (5mL) should suffice, though everyone has different body types. Less is more. Just a few mL.

Consider the nature of your substance. If you received it from a vendor in powdered form, it behooves you to perform a simple rinse/purification/acid-base extraction (my recommendation on all tolerant amines) if appropriate to launder the compound at least to an extent that you know that it doesn't have things like dirt in it. At that point, If your solution is water, consider the pKA's of any loose hydrogens that could be acidic in solution (Phenol was mentioned in an earlier post). It's not very likely that the amount of compound will significantly alter the pH of the solution. I will point out randomly that if someone wanted to administer Phenibut rectally, he would have a difficult time -- the solution would be acidic and caustic to mucus membranes.

In the case of mixtures, I can't say. They seem to be adsorbed as if they were in solution.
 
I stumbled upon this old article in the journal Ethnopharmacology. It discusses the rectal administration of psychaoctives in aboriginal practices. Seems like this method has been in circulation for quite some time and in many places.


Peter A.G.M. de Smet, 1983, "A MULTIDISCIPLINARY OVERVIEW OF INTOXICATING ENEMA RITUALS IN THE WESTERN HEMISPHERE" Ethnopharmacology P Vol. 9 p.19 -166

From pre-Hispanic times until the present day the indigenous inhabitants of the Americas have used intoxicating, often hallucinogenic dosage forms as aids to enter supernatural realms, i.e. as facilitating agents in religious trance induction, divination, witchcraft and healing ceremonies (Furst 1976; Emboden, 1979a; Schultes and Hofmann, 1980a,b; Schultes, 1981). It is equally well known that various Indian tribes and peoples, including several pre-Hispanic ones, employed the enema (Nordenskiold, 1930; Hallowell, 1935; Heizer, 1944; Was&n, 1972b; Furst and Coe, 1977). While it is therefore not surprising that various publications on American aboriginals contain information about the ritual rectal taking of intoxicating preparations, there does not appear to be an elaborate multidisciplinary survey on this subject. In an attempt to fill this gap, brief articles about South American Anadenantheru enemas (de Smet, 1981a) and about enema scenes on ancient Maya pottery (de Smet, 1981b) have been extended to the present more comprehensive overview which offers not only substantial and unsubstantial ethnobotanical data on the ritual use of intoxicating enemas in the western hemisphere, but also a pharmacological view on such practices.
 
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