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Phenethylamines The Big & Dandy Bromo-Dragonfly/DOB-Dragonfly Thread

Can anyone find me this paper??

[Bromo-dragon fly--life-threatening drug. Can cause tissue necrosis as demonstrated by the first described case][Article in Swedish]
Thorlacius K, Borna C, Personne M.
Anestesi- och intensivvårdskliniken, Universitetssjukhuset i Lund.

I dont speak swedish, but I know someone who was born in sweden and it is his first language. He would be happy to translate:)

Seems like something we should look into if it does cause tissue necrosis; even an abstract for it would be GREATLY appreciated...
 
Alright, I just looked up the article for you. Here is the link.

http://ltarkiv.lakartidningen.se/2008/temp/pda34918.pdf

I hope I'm allowed to post that, especially since it's in the spirit of harm reduction. Now those are some disturbing pictures in that article. I'm going to try and use an online translator to read it, but I'm really interested a real translation.

Dear god those pictures look bad...

Edit: Well so far, I'm through half the article really poorly translated. Not incredibly useful so far because there has been no information on how much was taken. I believe it was a 35 year old man who went over to his friends place. They both took Bromo-DFly that they had obtained from the internet.

The one guy was found dead, other has no memory of the event but was able to walk. Was in the hospital for a couple of days and they gave him some benzos and a bunch of other poorly translated medications I can't understand to try and stabilize him. Low blood pressure and other things I guess. He still had really bad "vasospasm" which I think means vasoconstriction.

They gave him three vascodilators and a couple other things that didn't translate well, but none of them had much effect. He was in the hospital for 9 days by this point, and by the 10th day he could go to some sort of "hemodialys" unit and out of intensive care.

7 weeks after it became neccasarry to amputate his fingers off his left hand and he still had gangreen in two toes on his left foot. That's all I've gotten through so far.

I think we can say that Bromo-Dragonfly has vasoconstrictive properties... hmm...
 
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I'm reading through the discussion right now and it was verified as Bromo-DFly through urine sample.

This is also important:

"It is not well-known how big dose it hit occupied, but according to letters to the editor on Internetforumet Flashback learns he and his friend have done a miss assessment off the amount, with a grave overdose that consequence"

It also says there was another person who overdosed by taking 2.5-3mg and was hospitalized, but fully recovered.

I don't quite understand this part, but it says that the vasoconstriction is probably caused by prolonged stimulation of the "alfa-1" receptor. A DOB overdose a similar thing but was fixed by Tolazoline.

That's everything of interest I think. That's my interpretation from an online translator, so it could be slightly off.
 
Keep in mind that DOB itself has vasoconstrictive properties at moderate to strong dosages, and there may be reason to believe that "tying its wings" a la B-DFLY would potentiate this effect.

I've heard--and can't reliably confirm--that the deceased ingested on the order of 8-10 mg of the R-(-) stereoisomer of B-DFLY, aka the "European Batch," i.e., the more potent and psychoactive isomer.

If so, such a dose would be about 16-40 times what a sensible, knowledgeable, and responsible person would ingest.
 
Scary shit. If I recall correctly, DOB has profound vasoconstrictive effects in higher doses, far in excess of those produced even by DOI, DOC or any of the TMAs. Hence, it is quite toxic in overdose and can certainly be fatal. DOB is a strong, full agonist at 5-HT2A, 2B and 2C receptors (producing at least 100% of the receptor activation of 5-HT itself), whereas DOI is a high-end partial agonist (~70% activation compared with 5-HT) and the tryptamines/ergoloids are lower-end partial agonists (~40% activation). Considering the full agonist profile at the 5-HT2B receptor, I wouldn't be surprised if DOB could also cause cardiac problems. Either way, it sounds like the bromo-phenethylamines (aside from 2C-B, which is a very weak partial agonist at 5-HT2 receptors) are best avoided. I wonder if chloro-FLY or methyl-FLY would be safer.

Edit: tobala, you beat me to the punch. I remember hearing about a DOB related death (from vascular collapse) where a person took a ~150mg dose, thinking it was MDMA.
 
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tobala said:
I've heard--and can't reliably confirm--that the deceased ingested on the order of 8-10 mg of the R-(-) stereoisomer of B-DFLY, aka the "European Batch," i.e., the more potent and psychoactive isomer.

If so, such a dose would be about 16-40 times what a sensible, knowledgeable, and responsible person would ingest.

The dose is a very important question, and 8-10mg is a huge amount. The fact that it could cause amputations in a non fatal overdose is pretty incredible though.

The various isomers and misinformation on this drug makes it hard to understand what's what with this drug.
 
And what happened to that individual who took both isomers up to 16mg repeatedly?f&b?
 
per tab brdf dose?

were a hypothetical apprentice to lay some of the Eurobatch BRDF on blotter paper, what would you, my esteemed intrepids, suggest as a reasonable number of micrograms per tab?

thanks, i just fear he may have made them a bit strong.
 
800mics-1mg.

seems like the right dose for activity without going over board.

I think it would safer for you to say what they were laid at though.
 
Thorlacius K, Borna C, Personne M. Bromo-dragon fly--life-threatening drug. Can cause tissue necrosis as demonstrated by the first described case. 2008. Lakartidningen. 105(16):1199-200. [Article in Swedish]

This article surfaced a few months back. I'm not sure of the details or the relevance since many others have taken the compound with no obvious issues. Either way, I plan to keep my distance for the time being.

Just realized the article is on Erowid and refers to the same case mentioned above. http://www.erowid.org/references/refs_view.php?A=ShowDoc1&ID=7343
 
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has this article been translate into english?
please, we do need this info.
i would be really surprized if an oral dose of a drug caused tissue necrosis.
if so, this we would really need to know
now, if this was an injection, yes, there are a number of substances that cause local necrosis, especially if they go into the "wrong" place.....im as opposed to iv or such
 
it appear that the user took a overdose and for some time experienced vascular constriction after the effects wore up but didn't get medical attention soon enough.
 
BTW I got my information from

The toxicity of Bromo-DragonFLY is unknown for humans however at least three reports of death believed to be resulted from Bromo-DragonFLY have been reported in Norway[3], Sweden[4] and Denmark[5]

Also, a Swedish man had to have the front part of his feet and several fingers on one hand amputated after taking a massive overdose. Apparently the compound acted as a long-acting efficacious vasoconstrictor, leading to necrosis and gangrene which was delayed by several weeks after the overdose occurred. Several other cases have also been reported of severe peripheral vasoconstriction following overdose with Bromo-DragonFLY, and a similar case is also known from DOB. Treatment was of limited efficacy in this case although tolazoline is reportedly an effective treatment where available.[6][7]

Overdoses, disturbing experiences, and Bromo-DragonFLY associated health problems have been described. One case in 2008 in England involved inhalation of vomit, causing nearly fatal asphyxia.[8]

I always said this was a compound I wasn't willing to tangle with.
 
Wow the guy did a licked finger print of bromo-dragonfly, that's the first I'd heard of that!

The article claims this could be "5-10mg" of the chemical but if the guy really did do a fingerprint, who knows, it could have been as high as 50mg.

Still, this is a chemical I will never be putting into my body.
 
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