For anyone who sees how much more dangerous 2C-T's (and expectedly ALEPHs) can be when compared to non-sulphur containing homologs, man these are kind of scary to think about. I wonder how many (if any) exhibit MAO inhibition.
(2-Aminopropyl)benzo[β]thiophenes (APBTs) are novel monoamine transporter ligands that lack stimulant effects but display psychedelic-like activity in mice - Neuropsychopharmacology
Derivatives of (2-aminopropyl)indole (API) and (2-aminopropyl)benzofuran (APB) are new psychoactive substances which produce stimulant effects in vivo. (2-Aminopropyl)benzo[β]thiophene (APBT) is a novel sulfur-based analog of API and APB that has not been pharmacologically characterized. In the...www.nature.com
According to this article benzothiophene based "amphetamines" are more potent releasers of serotonin than their benzofuranyl analogs. They also have a higher affinity for the 5-ht-2 receptors and cause rats to develop the stereotype head twitch which indicates psychedelic like activity.
Benzothiophenes are just like benzofurans except benzothiophenes have a sulfer where benzofurans have an oxygen (and indoles have a nitrogen).
The three chemicals that they picked out to highlight were 3-APBT, 5-APBT, and 6-APBT.
5 and 6-APBT are...
