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The Big & Dandy 25I-NBOMe Thread (2nd edition)

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^ funny you say neon, I would totally concur in my experiences with 25i (my aura manifests in neon colors of pink, turquoise, and yellow). I also feel the same as you, while I do not have 15 years (rather 3-4) of psychedelic experience, this chemical has left me similarly 'awestruck' one might say. Throw in some aMT and it's really a party..
 
To start with:
As far as names go, drugs like 25I-NBOMe and other NBOMe's are often colliquially shortened to 25I (two-five-i would correct as opposed to twentyfive-i but I guess we can all let that slide) for example. They don't belong on the streets and they should not have street names. If you aren't exact enough to keep a name like 25I separate from 25C and everything else, just like 2C-B is separate from 2C-I in a similar way... you probably have no business dealing with it in any other form than blotters that come with well known dosage levels and maybe not even at all.
Not trying to be an asshole or anything but these class of compounds don't lend themselves well to casual use with minimum investment of understanding.

Some stimulant that can be taken by the grams, eaten or snorted, and while not being healthy for you is still tolerated... call that by street names and see if I care. But these are scientific 'tools' that have escaped from the lab, not intended or designed to be fit for a wide consumer market.

To make it a little more confusing, just know that there are other similar drugs that also start with "25I" but are other customizations. Examples are 25I-NBOH, 25I-NBMD and 25I-NBF. You don't have to remember them specifically, just know that a nickname 25I is not 100% specific and selective purely as an abbreviation.

What is it? I guess the wikipedia page sums up the basics as well as is basically necessary:

25I-NBOMe (NBOMe-2C-I, BOM-CI, Cimbi-5, Solaris) is a derivative of the phenethylamine hallucinogen 2C-I, discovered in 2003 by Ralf Heim at the Free University of Berlin,[1] and subsequently investigated in more detail by a team at Purdue University led by David Nichols.[2]
25I-NBOMe acts as a highly potent agonist for the human 5-HT2A receptor,[3][4] with a Ki of 0.044 nM, making it some sixteen times the potency of 2C-I itself, and a radiolabelled form of 25I-NBOMe can be used for mapping the distribution of 5-HT2A receptors in the brain.[5] In vitro tests showed this compound acted as an agonist but animal studies have not been reported. While the N-benzyl derivatives of 2C-I were significantly increased in potency compared to 2C-I, the N-benzyl derivatives of DOI were inactive.[6]
The carbon-11 labelled version of this compound ([11C]Cimbi-5) was synthesized and validated as a radiotracer for positron emission tomography (PET) in Copenhagen.[7] Being the first 5-HT2A receptor agonist PET radioligand, [11C]Cimbi-5 showed promise to yield a more functional marker of these receptors which are involved in human disease such as depression and schizophrenia.
Anecdotal reports from human users suggest 25I-NBOMe to be an active hallucinogen at a dose of as little as 500 mcg, making it a similar potency to other phenethylamine derived hallucinogens such as bromo-dragonfly.[citation needed] It came to media attention in early 2012 after a cluster of seven non-fatal overdoses with the drug, in or around Richmond, Virginia.[8][9][10] The drug is not active orally and must be taken buccally, sublingually or smoked, snorted (not recommended) as it is active at as low as 300 mcg that way.

Effects

Strong visuals occur (small patterns begin moving and some objects may appear as 2D)
Feelings of love, as well as sexual thoughts
Unpleasant chemical taste in your mouth (not eased by drinking any liquids)
Mild anxiety
Nausea, abdominal pain
Time perception is affected
Confusion (extreme confusion and panic in higher doses)

But to make perhaps for a more readable text:

It is a psychedelic drug made up of 2C-I with an extra piece attached to the chemical molecular structure.
This makes it much much more potent than 2C-I and changes the effects quite a bit to be more purely psychedelic, it is more selective in the way it acts.
Nonetheless there are still side-effects, depending on dosage and varying between people. Consider keeping the dose limited of vital essence. Just like DOX-compounds (for example DOI) it can fuck you up mentally, be dangerous physically, and last pretty long.
The dose starts at 300-500 ug, that is micrograms not milligrams. I mean HALF a milligram here.

Plenty of people have described the potential for visuals even higher than the psychedelic standard: LSD. Whether they are also more pleasant and interesting is up for debate. The mental effects seem to remain more clear-headed and manageable compared to other seriously potent trips. Also there seems to be good potential for empathogenic effects and mild to moderate stimulant effects in some.

It has an extremely short history of use, and the potential way of what happens in an overdose is not well understood at all. Handling the chemical can be dangerous for those who are not skilled since it is so potent, at least/especially in pure powder form. Blotter can be handled better but proper identification of compound and dosage have to be accurately passed on as included info with a batch.

Do NOT fuck with it, do not think you can get away with something like trying to eat just what looks like a tiny bit of powder. Do not eyeball this. Do not even weigh it without a sophisticated way of measuring an ingestible amount and form of it. Again: with blotters, someone else has already done this for you.

Also know that it is inactive eaten, but is active held under the tongue and between gums - in the mouth for a while, say 15-20 minutes. It is also active by nose but this requires special preparations.


(Frankly I would not trust the average dude laying 25I blotter to know how the hell to do it properly compared to the average LSD blotter laying dude. No noob lays acid. But any dumbass can order this and try to pull it off.)
 
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^ dude about summed it up.

^ funny you say neon, I would totally concur in my experiences with 25i (my aura manifests in neon colors of pink, turquoise, and yellow). I also feel the same as you, while I do not have 15 years (rather 3-4) of psychedelic experience, this chemical has left me similarly 'awestruck' one might say. Throw in some aMT and it's really a party..
Funny you should say AMT.
I have read AMT reports and this 25i seemed to me like what some of those may sound like... but a bit smoother. lol (not quite so gory?... more enlightening but extremely rapid and neon lol)
I was gonna say "that felt like aMT".. but I've never done aMT.
Heh. whatever.
Guinea pig, over an out. =P
 
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I accidentaly breathed in some of the powder, tripped so hard. Met my own death several times, pure grief and fear. Jesus christ
 
I accidentaly breathed in some of the powder, tripped so hard. Met my own death several times, pure grief and fear. Jesus christ

Even AFTER following the experience of eye_wide_open only the day before?

This is going to be one long summer full of 25i headlines........LOL
 
Sadly im sure there will be many accidental overdoses, from what I've heard it's an absolutely great substance and heard nothing but good experiences and trips. Sadly, everyone reads one tek and instantly becomes Albert Hoffman and try's measuring out and laying doses in there bedroom. Water measuring seems to be the safest and most effective. As for laying a dose and storing for a trip you plan, what are some good options to lay the dose out on?let's say a 500ug dose or 1ML of water solution. Sugar cubes? Feedback is appreciated :D
 
(Frankly I would not trust the average dude laying 25I blotter to know how the hell to do it properly compared to the average LSD blotter laying dude. No noob lays acid. But any dumbass can order this and try to pull it off.)

I'm gonna have to disagree with this Solipsis, just IME, LSD layers are just as retarded, the hits often come totally variable in potency because of inexact laying and drying methods. It's just LSD layers can get away with more retarded shit because the safety profile is so awesome for LSD. The kind of variability from these imprecise methods when 25i is layed can have much more devastating negative effects.
 
^ dude about summed it up.


Funny you should say AMT.
I have read AMT reports and this 25i seemed to me like what some of those may sound like... but a bit smoother. lol (not quite so gory?... more enlightening but extremely rapid and neon lol)
I was gonna say "that felt like aMT".. but I've never done aMT.
Heh. whatever.
Guinea pig, over an out. =P

In my experience they're very very different psychedelics and it'd be hard to find any comparisons between them, other than the fact both can be intensely euphoric in the right setting, unlike a lot of other psychedelics.

As for how people lay this, while I agree that some people laying LSD aren't very good at it, but with 25I-NBOMe being incredibly easy for even some 15 year old who's never tried it before to get their hands on and lay onto blotter, there are going to be far more mistakes made and that combined with this not having anywhere near the safety profile of LSD is going to lead to a lot of people getting hurt I think.
 
I'm gonna have to disagree with this Solipsis, just IME, LSD layers are just as retarded, the hits often come totally variable in potency because of inexact laying and drying methods. It's just LSD layers can get away with more retarded shit because the safety profile is so awesome for LSD. The kind of variability from these imprecise methods when 25i is layed can have much more devastating negative effects.


I'd be interested how you could know for a fact that is true not only for the region (you can draw a big radius) around you but the rest of the world as well? Do you know - no need to share with us how - that these methods used are indeed wrong or are you inferring this from the quality of product you are handed?

In all fairness, I am only basing this on assumptions as well, namely that the availability of LSD crystal is protected enough to filter out a number of ignorants and leave the committed ones who understand how to do it, learn from being showed or are persistent enough to get it right. I associate those things and think it's very different from NBOMe's which due to public availability you know everyone has access to.
Should we similarly assume that the only ones who are going to be attempting to lay blotter with easily procured NBOMe's have a correlated subset of probable character traits? In other words is the same percentage of dumbasses weeded out?

Logical patterns speak to me more than anecdotal / small scale evidence does.

Your argument about LSD layers being able to get away with much more is solid, but it is entirely without proof that LSD layers need to get away with anything. My experiences with LSD sheets or part of them, over the years, is quite positive regarding the care used to make it.

So I am not saying I refuse to believe you, I am asking you what your evidence and reasoning is because it makes absolutely all the difference. My acid has been good, yours has been bad. You may be cursed by retarded people in your whereabouts or there may be something else I am not seeing. Like the possibility that my contacts have always ignored available bad acid and selected the good batches.

@Pengus, have you listed physical side-effects that were potentially dangerous when you breathed in the compound, in this thread already? Otherwise I'd like to hear it. People with - sorry to say - moronic bad experiences or even trainwrecks are welcome to recall what happened and recount symptoms in particular.
I couldn't care less about disrespectful posts (up to a certain point of proper conduct of course, as always!) or anger about the danger you put yourself and the community (maybe firstly the scientific one but of course also ours) into...
Your mistakes can prevent future mistakes!

As for how people lay this, while I agree that some people laying LSD aren't very good at it, but with 25I-NBOMe being incredibly easy for even some 15 year old who's never tried it before to get their hands on and lay onto blotter, there are going to be far more mistakes made and that combined with this not having anywhere near the safety profile of LSD is going to lead to a lot of people getting hurt I think.

Agreed, but I approached this the other way around, not from the perspective of random blotter and the possibility of a 15-year old, but a psychedelic user who hopefully is warned after what can be read in PD and the possibility of a blotter with known dose.

Well, your own personal measuring skills can trump untrustworthy badly laid NBOMe blotters - yes it's possible.
Or proper homogeneous NBOMe blotters can trump personal skills of a user, or what is more likely: the lack thereof.

So going on the chance that a random willing person is able to safely figure out how to handle powder, I made the judgement that blotter may actually be preferred on average over suggesting that people figure it out.
If both powder and blotter are available to a user and you do not have the info that this user has any experience or skills with chem handling, which ones are you more likely to suggest to this user, JG? :)
 
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If this isn't banned by the time the year is out, the gears will be in motion. It is too potent to be on general sale. This market is in desperate need of regulation.
 
I have been in this scene since 1999. I feel I dont have the equipment and experience to handle these materials safely. I do have interest in these substances but if I decide to conduct research I will be procuring pre-laid material. Hopefully those of us who have concerns with this material will be proven wrong. Do we have any idea what a lethal dose would be?
 
I'd actually prefer to lay some good ol LSD any day to this shit.
LSD has to be a million times safer lol. I've done a lot of LSD in my times and never seen anything like that.

I know how and where to get LSD liquid and crystal. I'm just afraid to be fucking around with that shit.
Don't know what makes me think i should be fucking with 25i-NBOMe either.
I think I had a fair experience and amount of safety with laying DOC onto newspaper so thought I would give it a shot.
It was surely a mistake.
the 25i-NBOMe was surely dirt cheap in comparison to black marketing some LSD to.

I'll be thinking long and hard before I ever open that bag again. haha.
It wasn't so bad though, just extremely surprising. It was pretty fun actually.
Hope Pengus is OK, tried to warn you guys.
I'm not afraid to admit when I messed up if it does help somebody.
I suppose somebody was bound to try it too, with the shit sitting there for sale like that.
Just glad it was me and nothing happened to me and not somebody else.
Hope you guys really try and listen to my warnings and now Pengus warnings too!
also Jasperthereckless.

Just opening the bag will fuck you up!
not kidding!


Makes me think if you want to play with shit like this you really should be having micropipettes an all that shit. Real labcoats, real mixing devices, clean rooms... the works. Gas masks?
$300 for a tool isn't anything if you want to try and get it all right every time without playing russian roulette and hurting yourself in a very crazy intense type of way.

I would imagine people who really lay LSD blotters often and successfully lay 25i-NBOMe understand safety is more important and a $300 tool or whatever it takes to stay safe and stay alive and out of the hospital would be pissing in the wind in comparison. Don't even bother trying to beat around the bush on the cheap with this stuff. this is why real LSD takes a lab to create.

Don't even think of trying to pass his off on your friends either I'd be way pissed off if somebody did that to me.
 
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I'd actually prefer to lay some good ol LSD any day to this shit.
LSD has to be a million times safer lol. I've done a lot of LSD in my times and never seen anything like that.

I know how and where to get LSD liquid and crystal. I'm just afraid to be fucking around with that shit.
Don't know what makes me think i should be fucking with 25i-NBOMe either.
I think I had a fair experience and amount of safety with laying DOC onto newspaper so thought I would give it a shot.
It was surely a mistake.
the 25i-NBOMe was surely dirt cheap in comparison to black marketing some LSD to.

I'll be thinking long and hard before I ever open that bag again. haha.
It wasn't so bad though, just extremely surprising. It was pretty fun actually.
Hope Pengus is OK, tried to warn you guys.
I'm not afraid to admit when I messed up if it does help somebody.
I suppose somebody was bound to try it too, with the shit sitting there for sale like that.
Just glad it was me and nothing happened to me and not somebody else.
Hope you guys really try and listen to my warnings and now Pengus warnings too!
also Jasperthereckless.

Just opening the bag will fuck you up!
not kidding!


Makes me think if you want to play with shit like this you really should be having micropipettes an all that shit. Real labcoats, real mixing devices, clean rooms... the works. Gas masks?
$300 for a tool isn't anything if you want to try and get it all right every time without playing russian roulette and hurting yourself in a very crazy intense type of way.

I would imagine people who really lay LSD blotters often and successfully lay 25i-NBOMe understand safety is more important and a $300 tool or whatever it takes to stay safe and stay alive and out of the hospital would be pissing in the wind in comparison. Don't even bother trying to beat around the bush on the cheap with this stuff. this is why real LSD takes a lab to create.

Don't even think of trying to pass his off on your friends either I'd be way pissed off if somebody did that to me.
Man, I wish people would listen to my ramblings and preachings against these amateurish attempts of laying blotters. There's not much reason for it with these substances. I really know what I'm talking about when it comes to this technique and it's dangers. Plus their bioavailability is so damn variable even within individuals that it seems a relatively unsafe drug in the first place. What pisses me off the most is that 2 out of 3 users are probably trying to make money with the stuff and bluelight is supporting these plans. Imho, you just cannot expect users who do not understand the basic principles of evenly distributing a water soluble solid within paper to be aware of the many ways a mg of substance can unwillingly enter your body. Sometimes I just cannot explain it and have to guess that substance somehow penetrated a weak spot in my skin barrier (wound?). It is dangerous as fuck and while millions of blotters can be layed with great care, without any intoxication taking place, you should still expect and be prepared for the worst when you are handling what i assume to be gram amounts of a substance this motherfucking active.
Keeping a benzo or some trazodone or whatever at hand would be a good idea. Basically if you are manufacturing an ingestable form of a drug, you will be fucked if you have to call the ambulance. Have fun getting rid of evidence before the ambulance arrives (while navigating your body through an ocean of pretty-colored hyperdimensional puke).

When people ask me about it, I usually tell them it is IMPOSSIBLE to do thiswithout receiving a fat dose, so they don't even get the idea of doing anything they will regret later. Imho, sometimes lying is the best way of speaking the truth, because people just dont hear the truth. On here I've just tried to expose all the idotic advice (blow air onto it with a fan was one of my favourites and the dude was holding onto it... playing with lives there) and generally warn about the process and the senselessness of putting nbome's on blotters (unless for commercial purposes...).

thanks for speaking some truth here and informing people about the dangers of what they are playing with. i hope you learned your lesson, ive had my fair share of involuntary intoxications. its a shame my lab explosion thread got deleted, eventhough it had already been brought to the attention of the authorities. twas a great thread, probably the only great thread ive ever created lol :(


edit: why do fucking morons never listen when you are giving some well-meant advice?! 3 bl users with large involuntary doses now?? ive even tried to bring this to the moderators' attention, the blotter discussion specifically.
 
Come on people wise up. This isn't the first psychedelic in microgram dosage, it doesn't take rocket science or extensive knowledge to be able to dose this correctly. All it takes is a set of scales and some sort of liquid to dissolve it in along with an oral syringe. If you seriously laid blotter with gloves/goggles/etc and STILL managed to dose yourself I ask what the hell are you doing.

I had 25c-NBOME and casually did this process without any sort of safety equipment and had no problem. I'm in no way trying to dicksize or encouraging this (harm reduction always) but you are only being careless if things like this are happening. Just do your research!

For those talking about a difference between laying LSD and this experience wise, there is none. Have any of you came across a vial of LSD? You can take the dropper and lay your own blotter the exact same way. The main difference is that blotter is heavily associated with LSD and so for the sake of safety this shouldn't be happening - but it is. Alongside that there is a higher chance of a seizure at more lower doses in the mg range, but like I said this stuff isn't rocket science use syringes and work out your measurements before doing it. People just sound careless to me in this thread.
 
I'd say you have either spent years of your life in lab environments or you were just lucky.

Really though, the problem is of course easily solved with great care. Most people lack respect though, therefore they become careless.
That's what I was saying about people never hearing the truth. They'll always interprete what you say, e.g. play it down in favor of whatever goal they are pursuing. That's why I can't stress enough how dangerous this shit is. Ofc, you won't need to tell a professional this, but remember many of these people I am referring to are probably not even 18 yet... :/ Warn boldly, leave a slight impression, a memory. Just tell them to be careful and youll just receive an answer like "yeah im always careful" (= whatever dude, keep talking lol...)

and when we are talking about laying acid blotters, i doubt anyone will drop 1 mio hits with a dropper vial lol. see, imagine having a kg of whatever substance or just 100g acid. first you need a container large enough to dissolve it all. how are you gonna pour it in? will there be particles in the air? how large will those particles be? will my mask hold them off or does enough air enter through the space between my nose and cheekbones to intoxicate me? can i see the smallest particles, taste them, smell them? remember acid can be absorbed through your skin if im not mistaken... in a lab environment none of those are factors to be considered, but we arent talking about lab environments. people dont prepare properly, instead they improvise, become impatient and hectic or just start slacking once theyve been safe for a while...
once youve dissolved a large amount of liquid, the rest of the process could be very tiring, maybe some people are even using drugs themselves in such an environment, mistakes are made. after the tenth time of changing gloves and masks someone might just have a drop land on your hand, you go pick your nose next time when the gloves are off. or maybe you roll a ciggie with seemingly dry gloves and vaporize some. there you go, now youre blasted lol.

its all fine in theory and you mightve always executed whatever youve done with care, especially when talking about a few hits or sheets, but when the experience is applied to processing large amounts of paper, additional care is needed, the process takes time and focus and energy. you never know what these kids are doing and where they are doing it. a lot of them do it under their parents roof and might compromise security in favor of staying under the parents' radar.

even if you assume no kids to be among the user base here, there is still a fluent transition from highly intelligent to absolutely retarded people. not everyone is as smart as e.g. you are.
 
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Come on people wise up. This isn't the first psychedelic in microgram dosage, it doesn't take rocket science or extensive knowledge to be able to dose this correctly. All it takes is a set of scales and some sort of liquid to dissolve it in along with an oral syringe. If you seriously laid blotter with gloves/goggles/etc and STILL managed to dose yourself I ask what the hell are you doing.

I had 25c-NBOME and casually did this process without any sort of safety equipment and had no problem. I'm in no way trying to dicksize or encouraging this (harm reduction always) but you are only being careless if things like this are happening. Just do your research!

For those talking about a difference between laying LSD and this experience wise, there is none. Have any of you came across a vial of LSD? You can take the dropper and lay your own blotter the exact same way. The main difference is that blotter is heavily associated with LSD and so for the sake of safety this shouldn't be happening - but it is. Alongside that there is a higher chance of a seizure at more lower doses in the mg range, but like I said this stuff isn't rocket science use syringes and work out your measurements before doing it. People just sound careless to me in this thread.

I have to say, I laid 25i and 25c blotters quite often (I would lay a blotter at a time when I felt like dosing) with minimal safety equipment as well and I never had any problems. Weird... I don't say that to recommend taking minimal safety precautions but I haven't heard of many people actually having these sorts of problems, so I found it a bit odd, but I guess I could have gotten lucky. Stay safe everyone.
 
I'm 99% sure I didn't spill any.
I never saw what I ingested.
It just happened.

I had 0 issues with DOC.

I think this stuff is really powerful.
I was trying really hard not to touch this stuff an have previously learned from other substances that eyeballing this stuff and adding an extra mg here or there is not acceptable. All that kind of thing.

Somehow, some way, I still ingested some.
It had to be like one crumb or something, I honestly have no idea.
I cleaned all my tools with alcohol, cleaned off my small workstation etc.
I mixed in a very tall vial and inside an air bubble in my dropper.

I was doing my best, but my best was not good enough for this substance, or this was an "unlucky attempt" and I know well enough to go attempting again after that! hehe.

I'm ok, I'm safe, I learned quite a bit about being a dumbass wannabe lab rat and I'm gonna leave it at that for a while for me.

I only imagine what could ave happened had I not been so protected.
I think that was life #5 of this cat's nine lives.
gonna go enjoy life now. lol

I feel kinda shitty I don't know how I messed up or what my doseage was to help you guys more. I also don't want to give this chemical a bad name.
I'm just far from equipped to lay this stuff and pretty much knew it to begin with but tried anyway.

A few people may think I over exaggerate a lot, I look at it as being extremely descriptive, inquisitive and truthful.
 
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I have to say, I laid 25i and 25c blotters quite often (I would lay a blotter at a time when I felt like dosing) with minimal safety equipment as well and I never had any problems. Weird... I don't say that to recommend taking minimal safety precautions but I haven't heard of many people actually having these sorts of problems, so I found it a bit odd, but I guess I could have gotten lucky. Stay safe everyone.

I also lay a single blotter with one dose whenever I want to do 25I. You'd have to be seriously lacking in common sense to screw that up -- unfortunately it seems the majority of people getting their hands on NBOMes are just that, lacking any common sense. I think everyone else talking about "laying blotter" are trying to do entire sheets at a time, which nobody should do unless they can ensure a consistent dosage for each piece of blotter. There's no good reason to lay an entire sheet of blotter for personal use, since it seems to keep well stored in a vial or in solution.
 
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