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The Big & Dandy 25I-NBOMe Thread (2nd edition)

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It is and there are indications that not everyone can tolerate multiple tens of milligram of these NBOMe compounds. Nobody should try this, if you need such high doses you are doing it too often, it should be sufficient to keep it at doses more like 1 mg.

Merging this into the main thread.
 
Alright I just got my bluelight account a few days ago but i have been reasearching drugs for years don't know very much chemistry but, I am smart and confident and I am about to undergo my next project and would like some advice proactiv advice please.
I have 60mg of 25inbome freebase I would like to make a solution and drop this onto blotter or whatever i please with a syringe and consume. I would like to make the acetate salt because it seems to be the simplest method to make 25i freebase orally active. I plan to use 6ml of vinegar and 6ml of distilled water to create the salt.

First question Should i let the solution evaperate into a solid salt before i dilute it more to drop accurate correct doses?

After what should I use to dilute it further or what would be best( i dont care about taste.) Should i use around 120ml of everclear 95% alcohol or vinegar or water or a combination?

Would there be any issues with making a solution with a combination of alcohol distilled water and vinager?

What are the benifits of Vinager,distilled water, and alcohol? (I heard both alcohol and vinegar help minimize bacteria.)
BTW i have read all the big and dandy 25i threads 1rst and 2nd I just want to make sure i make the best solution possible to consume buccal or sublingual.
 
By orally active you must mean sublingually. The acetate won't work when swallowed either, only dissolving / absorbing in your mouth and keeping it there for like > 15 minutes or nasal (or rectal) administration will remain as viable options.

Adding vinegar will allow the freebase to convert to the acetate salt which will be able to dissolve much better in polar solvents like water and alcohol. The advantage of alcohol and vinegar is also preservation/conservation but they need to have a certain minimum concentration. Best is to make the alcoholic portion 20% of the total volume or more. Excess of vinegar is unnecessary and not ideal as a preservative, it will also make it relatively nasty.

I don't think it's wise to try and lay blotter yourself. That kind of dosing method is sensitive to errors and drops are not an accurate volume to measure. Instead of a concentrated 5 mg/ml you can make it 1 mg/ml instead and use volumetric measurement with an oral syringe to measure doses to swoosh around in your mouth. Creating a concentrated liquid to administer intranasally is also possible but you should really do your homework on that kind of thing to make sure you are not overdosing.
It's safer to make it so that an average dose is 4 or 5 volumes administered by nose than trying to make it into 1 single unit. That way you can start lower. You can dilute a preparation as well to be able to gauge the strength of your preparation.
 
lastest said:
Nope, I've basically decided not to mess with these. For one thing, I'm not very good with practical stuff so I wouldn't trust myself to measure such tiny dosages accurately. It's a shame because they sound lovely, but I can live without them. Live being the operative word.
Click to expand...

I spent a couple of months reading everything I could find about the NBOMe series before I decided whether or not to work with them. It wasn't a decision I took lightly, but in the end I decided since I already had a good amount of experience doing liquid measurement with DOC that it wouldn't involve too much risk on my part, and given the glowing reports from others it sounded like it would be worth it to try it at least once (and it was!). Still, I was a little freaked out by the difference between my first trip at 500ug with only threshold effects, and my second trip at 800ug that was a +3/+4....It was only a difference of a few notches on my oral syringe, so I was amazed (and a little terrified) that that was all that was needed to push things into the stratosphere. 8o
 
Solipsis said:
By orally active you must mean sublingually. The acetate won't work when swallowed either, only dissolving / absorbing in your mouth and keeping it there for like > 15 minutes or nasal (or rectal) administration will remain as viable options.

Adding vinegar will allow the freebase to convert to the acetate salt which will be able to dissolve much better in polar solvents like water and alcohol. The advantage of alcohol and vinegar is also preservation/conservation but they need to have a certain minimum concentration. Best is to make the alcoholic portion 20% of the total volume or more. Excess of vinegar is unnecessary and not ideal as a preservative, it will also make it relatively nasty.

I don't think it's wise to try and lay blotter yourself. That kind of dosing method is sensitive to errors and drops are not an accurate volume to measure. Instead of a concentrated 5 mg/ml you can make it 1 mg/ml instead and use volumetric measurement with an oral syringe to measure doses to swoosh around in your mouth. Creating a concentrated liquid to administer intranasally is also possible but you should really do your homework on that kind of thing to make sure you are not overdosing.
It's safer to make it so that an average dose is 4 or 5 volumes administered by nose than trying to make it into 1 single unit. That way you can start lower. You can dilute a preparation as well to be able to gauge the strength of your preparation.
Click to expand...

Yes I did mean subligually and Ill be sure not use much vinegar. I plannned to use quite a bit of alcohol probably 40-50% of the solution because I want to put the solution in a freezer to store it and if theres too much water it would freeze. I think that I'll make a solution with 250mcg/1ml maybe even more diluted the only thing I worry about is the water color paper not abosorbing the whole 1ml or it getting into different squares. I also have thought about dropping it onto sour patch kids or sweet tarts for personal use. If I have gotten lsd like that i assume 25i solution could be put onto sweets too?
Has anyone used an insulin syringe to drop 1ml I'm curious as how difficult it would be to drop only 1ml at a time(I have never used a insulin syringe myself yet.)
 
So I have two 25i blotters, 500ug each. I'm planning on taking both of them and solo trippin' once I'm home for the summer. This isn't too much, right? It's going to be my first time with this substance, but I'm fairly experienced in terms of psychedelics in general.
 
It shouldn't be too much, but given the extreme reactions of some people here it might be better to start off with 500ug...
 
Hmm. I would, but I only have those two blotters, and I don't want to be underwhelmed.
 
if the blotters are not complexed I would assume your trip will not be overwhelming even at 1mg
 
Please keep in mind that these dosages via intranasal/rectal/invasive routes of administration are rather high, either with complexed substance or not. Starting lower is definitely advised, regardless of ROA.
Keep safe, be responsible :)
 
delltreeguy said:
I wanted to put a trip report on here. Over the course of 8 hours I have done over 20 mg's of 2C-I-NBOMe. WOW it was a great trip. I'm still tripping a bit. This is by far one of the coolest psychedelics out
there. I am amazed at the amount I did. I have no idea what LD50 of this stuff is, but I did an a lot. If anyone decides to do this stuff. Please be care full. This stuff is EXTREMELY potent. I started with
barely anything. So to all out there deciding to try this drug it's very easy to go overboard. Just have fun and be safe. Again be safe please. Yep.
Click to expand...

Seriously, no matter how great your trip was, no one should attempt these kind of doses. It can be potentially life-threatening and we don't wan't to see the NBOMe's banned now because of people taking heroic doses. This is not LSD, you'll end up in ER easily when overdoing this stuff.

800ug 25C-NBOMe intranasally was intense like hell for me, with serious ego loss, and while I still have 25I untested in my stack, the difference in potency between 25C and 25I is not that big (based on people's subjective experiences 25C-NBOMe seems to require a smaller dose though).
 
SONN said:
if the blotters are not complexed I would assume your trip will not be overwhelming even at 1mg
Click to expand...

I read Tregar's posts so I believed complexing is important so I ordered some 25C blotters complexed with cyclodextrin. I have some other blotters from a different vendor that were not complexed and the non complexed blotters were stronger. Maybe they carried more drug, I don't know. But in my experience I got good results with blotters there were not complexed.

I have a theory that under the tongue is not ideal because there's too much spit down there. You want to keep the saliva away from the blotter as much as you can because drug molecules that wind up in the saliva may end up wasted in the stomach instead of being absorbed into the mouth. So I apply them up high between the upper jaw and cheek after cleaning the area with a toothbrush first. Then I sit quietly without eating or drinking to keep the saliva away from the blotter.

Doing that I got the +3 on one 800 mic 25D un-complexed blotter but a few weeks earlier I only got to +2 1/2 on two 500 25C mic complexed blotter. There are several variables that could account for the difference. But still in my experience the blotters don't have to be complexed for good results.
 
biffhenderson said:
I read Tregar's posts so I believed complexing is important so I ordered some 25C blotters complexed with cyclodextrin. I have some other blotters from a different vendor that were not complexed and the non complexed blotters were stronger. Maybe they carried more drug, I don't know. But in my experience I got good results with blotters there were not complexed.

I have a theory that under the tongue is not ideal because there's too much spit down there. You want to keep the saliva away from the blotter as much as you can because drug molecules that wind up in the saliva may end up wasted in the stomach instead of being absorbed into the mouth. So I apply them up high between the upper jaw and cheek after cleaning the area with a toothbrush first. Then I sit quietly without eating or drinking to keep the saliva away from the blotter.

Doing that I got the +3 on one 800 mic 25D un-complexed blotter but a few weeks earlier I only got to +2 1/2 on two 500 25C mic complexed blotter. There are several variables that could account for the difference. But still in my experience the blotters don't have to be complexed for good results.
Click to expand...

A good trick I've noticed with NBOMe blotters is to keep your head a bit down, with your face downwards. This way saliva won't go into your throat as easily, even if you don't swallow for some 15-20 minutes.

A bit offtopic but how did 25D feel on your heart? I've found 25D to put a very heavy strain on my heart (with 800ucg), actually fearing for my heart a few times. I really don't like 25D anyway but it seems like the most stimulating of all the NBOMe's (at least I really hope 25I won't be as harsh on my heart).
 
Cyanoide said:
A bit offtopic but how did 25D feel on your heart? I've found 25D to put a very heavy strain on my heart (with 800ucg), actually fearing for my heart a few times. I really don't like 25D anyway but it seems like the most stimulating of all the NBOMe's (at least I really hope 25I won't be as harsh on my heart).
Click to expand...

I felt almost zero side effects on all three I tried 25C, 25I and 25D. As far as what's stimulating, reports seem to be all over. I found 25C to be the most energizing and 25D to be almost sedating but others like Coolio have reported different results. Maybe it's subjective. Maybe it's because I really don't push it on the dose.

Further testing is in order ;)
 
biffhenderson said:
I read Tregar's posts so I believed complexing is important so I ordered some 25C blotters complexed with cyclodextrin. I have some other blotters from a different vendor that were not complexed and the non complexed blotters were stronger. Maybe they carried more drug, I don't know. But in my experience I got good results with blotters there were not complexed.

Doing that I got the +3 on one 800 mic 25D un-complexed blotter but a few weeks earlier I only got to +2 1/2 on two 500 25C mic complexed blotter. There are several variables that could account for the difference. But still in my experience the blotters don't have to be complexed for good results.
Click to expand...
It only has to be complexed if it's freebase. The uncomplexed blotters you had that worked best was most certainly in the HCl form.
 
ok so i have gotten my hands on a couple vials of complexed 25i-nbome. i like the idea of having them put away in a storable form. can i drop these onto sour ppatch kids and expect a successful result?
 
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