Tested good MDMA did not work for me at all, infrequent user

[happygirl29]

I only roll very occasionaly , about twice or three times a year after a 13 year break of not rolling at all , I took 2 tested apples in a 15 hour period and they worked really well, about 3 weeks later I took an apple from exactly the same batch, all my friend came up , nothing happened at all, I took another half and still nothing. I then got a bit of teeth grinding and a headache and terrible stiff neck but no rush at all and no fuzzy feeling. I just felt really down and miserable. I had a difficult week prior to this with a lot of anxiety and had a small panic attack midweek. I did take gaba supplements and sceletium (kanna) during the week which calmed me down and I felt calm before I rolled why did they not work, is it something to do with seratonin or gaba? I have been anxious before when ive rolled yet everything normally worked? Any Ideas on the subject? I might add I had a horrific 20 hour bad experience on a white capsule a few years ago which prompted the anxiety and panic attacks initially.