Test E 500mg/week lifetime

M

Muslim

Greenlighter
Joined
Oct 26, 2015
Messages
1
Hey,


  • Age: 22 years
  • Weight: 198 lbs (90 kg)
  • Height: 185 cm
  • Activity: wrestling 4 times/week (7 hours total)
  • On high cal./high protein diet.

I am going to stay on Test E 500mg/week for lifetime.

The most important thing for me is, will I be able to have kids?
And why is it not a wise decision?

I'm 22, do not have a lot of life experience, I don't want your criticism, I here for advice.
 
If you dont want criticism then go ahead and do whatever you want

Your plan isnt a good one but you dont want criticism so i dunno if anyone is gonna help you
 
Do you want us all to tell you it would be a good idea? Clearly you know we won't or you wouldn't ask the question in that way.

Let's assume you do manage to have kids despite being on all the time. So maybe you have your first at about 30, and your second at 33. Then you die of a heart attack at 45 and your kids grow up without a father and your wife without a husband. That's going to be really nice for them. It's not an improbable outcome.

From the point of view of gains as well staying on cycle all the time is pointless because after a few months they'll stop. You'd be much better served cycling off and on and periodising your programme.

As for the health issues, it's not worth laboring these points since you probably won't listen. But to summarise some of the widely known short and long term health issues :

Cardiovascular disease (vascular)

Heart disease inc. hypertrophy and fibrosis, valvular disease etc.

Blood lipid changes (low HDL, high LOL, triglycerides etc) leading to atherosclerosis, fatty liver etc.

Insulin resistance (liver issues, ectopic fat deposition, zero muscle gains)

Hypertension and 'thick' blood

Thrombotic episodes (mild clots, severe clots and strokes, micro strokes, cerebrovascular disease)

Prostate hypertrophy and hyperplasia (leading to things like prostatitis and bladder infections as well)

Kidney disease (esp from high blood pressure)

Hairloss (and growth eg back hair)

Acne/skin problems (changes in dermis/epidermis)

Psychological issues (mood changes, chronic depression etc) and potential damage to cerebral tissue

Hormone imbalances (prolactin/dopamine ratio, oestrogen etc) leading to mood issues, gynecomastia etc.

Infertility and testicular atrophy

There are more but this is off the top of my head and are well worth worrying about (a lot)....
 
I'm honestly not sure if you expected....well, ANY replies to this thread given you don't want criticism. Unfortunately, that's what you'll get - constructive criticism - in the form of advice that will likely go against your plan.

500mg/wk is HIGH for cruising, especially for someone not already sporting supraphysiological muscle mass. It's overkill, and after a few months you'll notice a decline in the effects as homeostasis tries to balance everything out. Also 'tolerance' of sorts will have a play as the Androgen Receptor (AR) up-regulates (someone plz confirm it's UP-regulates, as opposed to typical receptor tolerance of down-regulation), essentially rendering the testosterone less effective by weight.
 
trozzle said:
I'm honestly not sure if you expected....well, ANY replies to this thread given you don't want criticism. Unfortunately, that's what you'll get - constructive criticism - in the form of advice that will likely go against your plan.

500mg/wk is HIGH for cruising, especially for someone not already sporting supraphysiological muscle mass. It's overkill, and after a few months you'll notice a decline in the effects as homeostasis tries to balance everything out. Also 'tolerance' of sorts will have a play as the Androgen Receptor (AR) up-regulates (someone plz confirm it's UP-regulates, as opposed to typical receptor tolerance of down-regulation), essentially rendering the testosterone less effective by weight.
Click to expand...

Initially, yes, there is an up-regulation of the AR but after sustained elevated testosterone levels some desensitization occurs which leads to a decrease in mRNA levels acting as a negative feedback loop...
 
Daz-69 said:
Initially, yes, there is an up-regulation of the AR but after sustained elevated testosterone levels some desensitization occurs which leads to a decrease in mRNA levels acting as a negative feedback loop...
Click to expand...

Cheers :)

I never understood how AAS can cause up-regulation on the receptor they act on, yet over time sensitivity decreases (which is what I'd always associated with DOWN-regulation).
 
Question for the up regulation and declining sensitivity: Do stronger androgens desensitize the receptors more rapidly at equal dosing: say 500 test e vs 500 tren e? Total amount of hormone is same but tren binds much more tightly.
 
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