Tell Me the Coolest Thing You Know About LSD

[Viraldrome]

There are no different types of LSD, it is LSD or not LSD, period. Needlepoint is just a marketing term, the idea you can tell different "types" of is wrong, its all placebo. The only difference is the dosages vary wildly from hit to hit. That is why one trip is so different than another. 200 mics and 300 mics are very different trips, so people think it must be different acid. If the people who sampled Sandoz said it was the same as street acid I take that as gospel. They should have been raving about the cleanest, purist LSD ever, and they said it was the same as street LSD https://www.erowid.org/chemicals/lsd/lsd_article2.shtml

 

[Deleted member 521610]

There are no different types of LSD, it is LSD or not LSD, period. Needlepoint is just a marketing term, the idea you can tell different "types" of is wrong, its all placebo. The only difference is the dosages vary wildly from hit to hit. That is why one trip is so different than another. 200 mics and 300 mics are very different trips, so people think it must be different acid. If the people who sampled Sandoz said it was the same as street acid I take that as gospel. They should have been raving about the cleanest, purist LSD ever, and they said it was the same as street LSD https://www.erowid.org/chemicals/lsd/lsd_article2.shtml

false

 

[blistersinthedark]

Viraldrome does have a point. Unless you have access to analysis equipment or facilities, labels like "needlepoint" and "fluff" don't mean anything. Sure, there might be a subjective difference between a crystal that is 99.9% pure d-LSD vs something that's 95% pure and contains some of the other isomers, but how exactly are you supposed to know that it's only purity and not dosage/set/setting that is the main factor behind those subjective differences if you don't have the technical means of verifying purity claims in the first place? I've had vastly different experiences from the same batch of LSD on numerous occasions, and I'm sure dosage is the biggest factor (i.e. uneven distribution on the blotter).

 

[Bitchniggaz]

Viraldrome does have a point. Unless you have access to analysis equipment or facilities, labels like "needlepoint" and "fluff" don't mean anything. Sure, there might be a subjective difference between a crystal that is 99.9% pure d-LSD vs something that's 95% pure and contains some of the other isomers, but how exactly are you supposed to know that it's only purity and not dosage/set/setting that is the main factor behind those subjective differences if you don't have the technical means of verifying purity claims in the first place? I've had vastly different experiences from the same batch of LSD on numerous occasions, and I'm sure dosage is the biggest factor (i.e. uneven distribution on the blotter).

A friend usually gets his stuff tested, there are some labs that do this.
The cheaper stuff def has more ISO lsd and other crap in it.

 

[Phobos]

There are no different types of LSD, it is LSD or not LSD, period. Needlepoint is just a marketing term, the idea you can tell different "types" of is wrong, its all placebo. The only difference is the dosages vary wildly from hit to hit. That is why one trip is so different than another. 200 mics and 300 mics are very different trips, so people think it must be different acid. If the people who sampled Sandoz said it was the same as street acid I take that as gospel. They should have been raving about the cleanest, purist LSD ever, and they said it was the same as street LSD https://www.erowid.org/chemicals/lsd/lsd_article2.shtml

What they said is that the specific street LSD they tried was the same as Sandoz, not that all LSD is the same.
I never had different experiences when taking doses from the same sheet, BTW.
The variations from sheet to sheet sometimes are just dose related, sometimes there is something else at play, and that something is consistent through the whole sheet.
These differences have always been confirmed by people I tripped with more than a hundred times without me giving my opinion before they would try the batch, and this matter has also been brought up many times here on BL.
Some impurities are known to cause variations in the experience, so yeah, LSD is LSD, but it's the impurities that can cause a difference in effects from one batch to another.

 

[t_wrex]

Recent research has brought us closer to understanding LSD's methods of action. In 2017, a paper was published that shed new light onto the area of LSD's long trip length:

The prototypical hallucinogen LSD acts via serotonin receptors, and here we describe the crystal structure of LSD in complex with the human serotonin receptor 5-HT2B. The complex reveals conformational rearrangements to accommodate LSD, providing a structural explanation for the conformational selectivity of LSD’s key diethylamide moiety. LSD dissociates exceptionally slowly from both 5-HT2BR and 5-HT2AR -- a major target for its psychoactivity. Molecular dynamics (MD) simulations suggest that LSD’s slow binding kinetics may be due to a “lid” formed by extracellular loop 2 (EL2) at the entrance to the binding pocket. A mutation predicted to increase the mobility of this lid greatly accelerates LSD’s binding kinetics and selectively dampens LSD-mediated β-arrestin2 recruitment. This study thus reveals an unexpected binding mode of LSD, illuminates key features of its kinetics, stereochemistry, and signaling, and provides a molecular explanation for LSD’s actions at human serotonin receptors.

Crystal structure of an LSD-bound human serotonin receptor - PMC

The prototypical hallucinogen LSD acts via serotonin receptors, and here we describe the crystal structure of LSD in complex with the human serotonin receptor 5-HT2B. The complex reveals conformational rearrangements to accommodate LSD, providing a ...

www.ncbi.nlm.nih.gov

For some reason, our 5-HT2 receptors trap the LSD inside them for an extended length of time. This apparently only happens with 1 of the stereoisomers; all the others do not produce the same trapping effect.

 

[Deleted member 521610]

I could give a person a selection of crystal that i know has been purified twice via chromatography dosed at accurate and a non purfied crude lsd product that has been dosed more to have the same amount of LSD as the pure one. Two same dosages the crude lsd prodcut will probably send you into psychosis if were dosing 300 ug and trapped in infinite time loops and make you retarded for the duration of the trip. While the pure lsd will activate you brain to super human iq levels and give you clear thought. In a blind test. When i graduated in chemistry there were PHD chemists wearing fucking tai dye lab coats with dreads. I have never seen more LSD in my life than the days when i was a student in undergrad chemistry sheets went around plenty for cheap.

 

[somnilicious]

I could give a person a selection of crystal that i know has been purified twice via chromatography dosed at accurate and a non purfied crude lsd product that has been dosed more to have the same amount of LSD as the pure one. Two same dosages the crude lsd prodcut will probably send you into psychosis if were dosing 300 ug and trapped in infinite time loops and make you retarded for the duration of the trip. While the pure lsd will activate you brain to super human iq levels and give you clear thought. In a blind test. When i graduated in chemistry there were PHD chemists wearing fucking tai dye lab coats with dreads. I have never seen more LSD in my life than the days when i was a student in undergrad chemistry sheets went around plenty for cheap.

I find all this very interesting. I always thought the subjective differences were based on setting and mindset but after having been away from cid for 17yrs, I have recently rediscovered the joy.

I lost all contacts shortly after the Pickard bust. In the 90's acid was everywhere. I used to go to a Florida national forest, where rainbow gathering hippies would campout. They traveled around the country living in national parks and forests and they would trade sheets of acid for small amounts of pot.

My experiences greatly varied and I heard all kinds of bullshit about strichnine and what not causing unpleasant effects. I always just assumed LSD was LSD but now all the other Lsyrgamides (sp) and talk of impurities has me thinking.

The cid I get has a route 25 sign on it so I assume it's 25 but who knows. It is extremely clean, clear headed, euphoric, loving and visually beautiful. I don't see how anyone could have a difficult trip on it. It has actually helped me overcome a lifetime addiction to heroin and a recent flirtation with kratom. I am so glad I have this gift in my life. I am afraid of losing the magic and having some of those rough confusing trips that I remember so well.

I have done shrooms a couple of times recently and this last trip was disorienting, introspective and had a darker feel, especially on the come up. I hope this is more of an aspect of the shroom experience and doesn't portend similar LSD experiences to come.

Supposed to get my next dip at the beginning of the week. I can't wait it's been about 3 weeks?... I guess this should be in the social because I'm rambling but I feel so excited and blessed. It has has been a game changer in my life.

Love all you guys.... Happy trips?

 

[Deleted member 521610]

I find all this very interesting. I always thought the subjective differences were based on setting and mindset but after having been away from cid for 17yrs, I have recently rediscovered the joy.

I lost all contacts shortly after the Pickard bust. In the 90's acid was everywhere. I used to go to a Florida national forest, where rainbow gathering hippies would campout. They traveled around the country living in national parks and forests and they would trade sheets of acid for small amounts of pot.

My experiences greatly varied and I heard all kinds of bullshit about strichnine and what not causing unpleasant effects. I always just assumed LSD was LSD but now all the other Lsyrgamides (sp) and talk of impurities has me thinking.

The cid I get has a route 25 sign on it so I assume it's 25 but who knows. It is extremely clean, clear headed, euphoric, loving and visually beautiful. I don't see how anyone could have a difficult trip on it. It has actually helped me overcome a lifetime addiction to heroin and a recent flirtation with kratom. I am so glad I have this gift in my life. I am afraid of losing the magic and having some of those rough confusing trips that I remember so well.

I have done shrooms a couple of times recently and this last trip was disorienting, introspective and had a darker feel, especially on the come up. I hope this is more of an aspect of the shroom experience and doesn't portend similar LSD experiences to come.

Supposed to get my next dip at the beginning of the week. I can't wait it's been about 3 weeks?... I guess this should be in the social because I'm rambling but I feel so excited and blessed. It has has been a game changer in my life.

Love all you guys.... Happy trips?

theres alot of very clean pure needlepoint lsd around these days which gives the clear head super mind loving time space distortion visuals

 

[cryptix420]

I find all this very interesting. I always thought the subjective differences were based on setting and mindset but after having been away from cid for 17yrs, I have recently rediscovered the joy.

I lost all contacts shortly after the Pickard bust. In the 90's acid was everywhere. I used to go to a Florida national forest, where rainbow gathering hippies would campout. They traveled around the country living in national parks and forests and they would trade sheets of acid for small amounts of pot.

My experiences greatly varied and I heard all kinds of bullshit about strichnine and what not causing unpleasant effects. I always just assumed LSD was LSD but now all the other Lsyrgamides (sp) and talk of impurities has me thinking.

The cid I get has a route 25 sign on it so I assume it's 25 but who knows. It is extremely clean, clear headed, euphoric, loving and visually beautiful. I don't see how anyone could have a difficult trip on it. It has actually helped me overcome a lifetime addiction to heroin and a recent flirtation with kratom. I am so glad I have this gift in my life. I am afraid of losing the magic and having some of those rough confusing trips that I remember so well.

I have done shrooms a couple of times recently and this last trip was disorienting, introspective and had a darker feel, especially on the come up. I hope this is more of an aspect of the shroom experience and doesn't portend similar LSD experiences to come.

Supposed to get my next dip at the beginning of the week. I can't wait it's been about 3 weeks?... I guess this should be in the social because I'm rambling but I feel so excited and blessed. It has has been a game changer in my life.

Love all you guys.... Happy trips?

A word to the wise about shrooms - the only way to experience psilocybin properly (imhfo) is dosing about 5g dry, or 50g fresh, laying in a dark room, putting on wordless music, and applying a blindfold. LSD is all about daylight and the OEVs. Shrooms are the opposite.

Additionally, if you'd like to skip the comeup, look into the lemon Tek.

 

[somnilicious]

A word to the wise about shrooms - the only way to experience psilocybin properly (imhfo) is dosing about 5g dry, or 50g fresh, laying in a dark room, putting on wordless music, and applying a blindfold. LSD is all about daylight and the OEVs. Shrooms are the opposite.

Additionally, if you'd like to skip the comeup, look into the lemon Tek.

Thanks for the suggestions. I don't know how far I want to go at my age, though I do plan on a DMT break through and an Ayahuasca retreat. I don't know if shrooms are my bag. I enjoy the smooth LSD ride more.

Probably a rookie question but do different shroom types give different effects other than dose difference?

 

[cryptix420]

Thanks for the suggestions. I don't know how far I want to go at my age, though I do plan on a DMT break through and an Ayahuasca retreat. I don't know if shrooms are my bag. I enjoy the smooth LSD ride more.

Probably a rookie question but do different shroom types give different effects other than dose difference?

Shrooms are certainly intense in the emotional department, but I find them much more gentle than LSD personally. But that's when I do it the blindfold way. Trying to have my eyes open is disorienting and weird. I love the time distortion effects though. Doing the lemon Tek is a lot like DMT honestly. And hell Ayahuasca is pretty much in the top 3 in terms of intensity imo.

Regarding differences, cyanescens are much more potent but often people report darker trips. Cubensis are essentially all the same experience, although personally I found dosing fresh shrooms far more colorful and euphoric and lighthearted than dry.

 

[Deleted member 521610]

Shrooms are certainly intense in the emotional department, but I find them much more gentle than LSD personally. But that's when I do it the blindfold way. Trying to have my eyes open is disorienting and weird. I love the time distortion effects though. Doing the lemon Tek is a lot like DMT honestly. And hell Ayahuasca is pretty much in the top 3 in terms of intensity imo.

Regarding differences, cyanescens are much more potent but often people report darker trips. Cubensis are essentially all the same experience, although personally I found dosing fresh shrooms far more colorful and euphoric and lighthearted than dry.

I eat psilocybe subaeruginosa i personally find LSD is alot darker than shrooms. LSD has shown me some hardcore hellish machinescape gore and hellfire. Shrooms do get very dark aswell in high doses. The most i ate was 8 grams dried which is equal to 13 grams dried of cubensis. The trip was just dark intense and honestly i gained nothing from it other than knowledge on how fucking intense shrooms can get.

 

[Chris Timothy]

The coolest thing about LSD I'm keeping a secret for now, because I don't want the news about some new opened avenues to spread too quickly! ? ?‍

 

[somnilicious]

I eat psilocybe subaeruginosa i personally find LSD is alot darker than shrooms. LSD has shown me some hardcore hellish machinescape gore and hellfire. Shrooms do get very dark aswell in high doses. The most i ate was 8 grams dried which is equal to 13 grams dried of cubensis. The trip was just dark intense and honestly i gained nothing from it other than knowledge on how fucking intense shrooms can get.

I keep it rather light with the LSD. I haven't taken more than one tab since I rediscovered it. All my trips have been extremely positive. I don't want to push it.

I do however strongly desire the to experience an official Ayahuasca ceremony. I'm nervous but excited about what it has to show me. I desire that revealing dream/nightmare trip that will force perspective and cleansing. I have had a very troubled path in life and I really believe my mind has incorrectly filtered my experiences and that my natural defence mechanisms have caused me to miss a a lot of the plot. I crave more of the reframing that LSD gave me. It was like 10yrs of therapy condensed into 10hrs.

 

[Xorkoth]

LSD is very unusual and interesting in that its half life is far shorter than its duration of action. Not many drugs can say that.

 

[heatlessbbq]

"The coolest thing I know about LSD"?...

It is microscopic.

 

[cryptix420]

LSD is very unusual and interesting in that its half life is far shorter than its duration of action. Not many drugs can say that.

Fascinating for sure. I've heard it metabolizes into several different types of LSD, increasing in variety as the dose goes higher.

Does phenibut also fall in this category?

And them there's drugs that are the opposite like benzodiazepines.

 

[Phobos]

LSD is very unusual and interesting in that its half life is far shorter than its duration of action. Not many drugs can say that.

By the way LSD locks in some serotonin receptors for a very long time, that makes sense, the rest of psychedelics just attach to receptors for a short amount of time and then leave the receptor, so there is a significant % of the drug that can get metabolised/filtered by kidneys at any point in time.
But with LSD, the plasma concentration and half life are going to behave differently: after come up, the drug will be bound to various receptors, but when it finds any 5HT2A and 5HT2B it's going to be locked in, so as time passes after ingestion it will get out of the other receptors and slowly starts to bind more to those 2 types.

 

[Deleted member 521610]

Anybody get the first false peak on LSD where its like the acid is just lying to you and you think to yourself o wow is this all it i has i should of popped another tab then the true peak hits 20 minutes later with utter destruction and everything is just fractal geometric patterns and heavy reality morphing of objects