[Tek] Theoretical infusion of JWH-018 into tobacco cigarettes

[Tilex]

For starters:
This is a theoretical infusion of JWH-018 (and related compounds) into cigarette tobacco (no need to remove / reroll cigarettes, with the addition of an oral syringe) that I developed today during organic chemistry lab. We were (as I recall) working on lipophilic compounds and solubility in common lab solvents as part of a titration experiment, and it gave me the idea being that most cannabinoids are extremely lipophilic and share the same solubility profiles.

The theoretical materials are:

• 1x cigarette per 2.5mg of JWH-018 or related compound.
• A known quantity of JWH-018 or related compound.
• 1 mL of VM&P Naptha/Acetone per 1 mg of JWH-018 or related compound.
• 1x oral syringe or related dosing device with a thin applicator.
• 1x beaker (can substitute for glassware, non-dyed and clear).
• 1x hot plate or other heating device.
• 1x stirring device (preferrably stainless steel if magnet is not available).
• 1x pot/pan to fill with water and use as a submersible vessel.

Before starting, take note of the following:
*BE SURE TO USE A WELL VENTILATED AREA WHEN DEALING WITH VOLATILE SOLVENTS SUCH AS NAPTHA/ACETONE ETC.
**ALWAYS ALLOW PROPER TIME TO EVAPORATE BEFORE USING FINISHED PRODUCT.
***NEVER WORK WITH TEMPERATURES GREATLY EXCEEDING THE BOILING POINT OF YOUR SOLVENT!

Procedure for infusion:

• Mix 1mL per mg of solvent / cannabinoid compound in beaker/glassware.
• Stir vigorously in a well-ventilated area until the majority of the compound has dissolved in the solvent.
• Partially submerge vessel in hot water pan for 5 (usually) to 10 minutes, or until the compound has been completely dissolved. *NOTE if already dissolved, allow for 50% degredation of the solution for less of a mess.
• Assuming 50% degredation has been achieved, the ratio is now 0.5 mL per mg. Smaller ratios/more degredation can be used to create a more potent mL/mg soln.
• Draw 5 mL into dosing device / syringe.
• Insert 1.25 mL into each cigarette, carefully inserting the device approximately 0.5-1cm past the initial layer of tobacco to allow for more efficient consumption.
• Allow a minimum of two, more likely 5-10 hours for evaporation in open air / less in heat.
• Get HIGH.

Approximate cost is ~0.75 dollars (75 cents) per dosage unit, depending on cigarette prices, solvent prices, equipment prices, and JWH prices. I have found in my experience that one can reduce this cost to ~50 cents when purchasing in large enough quantities.

Congratulations, you have just infused cigarettes with a JWH-related compound. Blast off

FAQ:
Why would you want to do this with tobacco?
*It has been proven that nicotine increases the absorption of THC related cannabinoids, and using this model one can hopefully infer that JWH related compounds will also be increased in bioavailability.

Why would you want to do this with a JWH compound?
*This is for those of us who are afraid of regular drug testing

How can I modify this process to achieve a better high?
*Mixing JWH/CP/WIN compounds has been shown to produce a high more similar to marijuana.

Why cigarettes? Why not roll your own?
*They're already rolled, and I'm lazy. Also, unless you're good at it, this will most certainly be more stealth, and less is lost when injecting directly into a medium rather than transferring it multiple times (e.g. rolling). This process provides the most marginal losses for a combustible product.

 

[Tilex]

If anyone tries this, please post results. The two tests I have used so far involved naptha as the solvent and JWH-018 as the cannabinoid compound, and were quite promising.

 

[Psychedelic Jay]

That sounds like a great time, Keep us posted.

 

[flacky]

I would be worried about the acetone leaching into the filter and making nasty things happen.

It might be a good idea to add the solution dropwise along both side of the cigarette stopping well before the filter...

 

[psychomimetic]

^Or you could use unfiltered cigs.

 

[flacky]

^ OP posted that he wants to be stealthy about it, thus the need for the filter.

 

[TheAzo]

1) Why the FUCK are you using naptha? Lets just use a MORE TOXIC, SLOWER EVAPORATING, LESS EFFECTIVE solvent than we could be using, just for the fun of it....
FFS, use acetone. It evepotates faster, and dissolves JWH-xxx and CP-xxx,yy at least an order of magnitude better, and doesnt give you a headache within 5 minutes of opening the can. Acetone is also more likely to be clean than naptha (in my experience, at least)

2) 1mg/ml is way the fuck too dilute for something like this. 10mg/ml is the lowest i'd think about going, otherwise you're going to have a soggy ciggy soaked in solvent, and when it finally dries (even ignoring the fact that your JWH has probably migrated to the paper, where most of it will be lost to the air), your cig will, well, look like it's been soaked in solvents, with "water lines" and shit.

3) Why not use a syringe with a needle (a course needle if you must - like what you'd use for precision application of epoxy; i have some points with that standard fitting on them that were purchaced for that purpose), and inject it, by inserting the needle along the axis?

 

[Tilex]

Going for the gold on this one, once the method is perfected I'll use higher amounts and post results. I just received 100mg of1-pentyl-3-(1-napththoyl)indole, about to run the third trial. Third time's a charm, if I can get it down with marginal losses perhaps I will try propylene glycol and my e-cigarette with more like a gram or two.

 

[Tilex]

1) Why the FUCK are you using naptha? Lets just use a MORE TOXIC, SLOWER EVAPORATING, LESS EFFECTIVE solvent than we could be using, just for the fun of it....
FFS, use acetone. It evepotates faster, and dissolves JWH-xxx and CP-xxx,yy at least an order of magnitude better, and doesnt give you a headache within 5 minutes of opening the can. Acetone is also more likely to be clean than naptha (in my experience, at least)

2) 1mg/ml is way the fuck too dilute for something like this. 10mg/ml is the lowest i'd think about going, otherwise you're going to have a soggy ciggy soaked in solvent, and when it finally dries (even ignoring the fact that your JWH has probably migrated to the paper, where most of it will be lost to the air), your cig will, well, look like it's been soaked in solvents, with "water lines" and shit.

3) Why not use a syringe with a needle (a course needle if you must - like what you'd use for precision application of epoxy; i have some points with that standard fitting on them that were purchaced for that purpose), and inject it, by inserting the needle along the axis?

No need to be harsh about it, we're all friends here
I forgot to mention that I did use acetone for the last trial, and I'm using acetone for the following as well. I don't have access to a needle due to strict laws in PA (needles are considered paraphernalia without a diabetes card/requiring condition). Also, I tried finding an epoxy needle, but apparently they aren't available anywhere near me as well, and due to the parents, cannot have needles mailed to me.

But duly noted, I will take your advice into consideration for the next trial, I suppose a 5-10mg/ml solution would be much easier to work with

 

[any major dude]

if i were to do this, i would use everclear. with gentle heat and enough agitation i haven't had any problems getting any JWH's to go into solution. All it requires is a 50mL flat bottom boiling flask ($3.50), some everclear, and a conduction stove or warm water bath.

I suggest using about a 5mg per mL solution and putting roughly half an mL on a cigarette, then letting it dry til there is no smell of ethanol left.

 

[Tilex]

if i were to do this, i would use everclear. with gentle heat and enough agitation i haven't had any problems getting any JWH's to go into solution. All it requires is a 50mL flat bottom boiling flask ($3.50), some everclear, and a conduction stove or warm water bath.

I suggest using about a 5mg per mL solution and putting roughly half an mL on a cigarette, then letting it dry til there is no smell of ethanol left.

After three experiments with acetone, I can say that the losses are between 25 and 40% if not handled correctly. Ethanol would probably make for a better solvent, sadly I'm 19 I'm going to lower the amount of acetone used per mg once more, cutting it in half to 20mg per mL, using 1/4 mL per cigarette for the next trial. Just awaiting JWH.

 

[any major dude]

ah, well being 19 is certainly the only legit reason for not using ethanol as a solvent well, that or living in saudi arabia.....Though since you're in college i don't imagine you'll have too much difficulty procuring some.

I haven't calculated product loss with ethanol, mostly because it doesn't appear to be large enough for me to bother, but if i were forced to make a rough guess based on subjective effects i'd estimate 10-20%, give or take.

I don't think you'd have trouble getting 20-30mg per mL in acetone. With 95% EtOH i haven't reached the upper limit of solubility yet and the most i've used was about 40mg of various jwh's in about 1.5mL

oh, and in lieu of a needle a marinade injector might work, could be too big for a cig though, I'm not sure. An antifreeze level checker could be purchased at autozone or somesuch and adapted for your purpose, i'm almost positive. A skinny pipette could likely be found with relative ease as well, especially if you're in a chem lab this semester. Though I would probably just use a mL metered medicine dropper and set the cigarette upright and slowly drip about .5mL down the end of it. Best way to smoke these is still a glass dick, but there are plenty of circumstances in which its ok to smoke a cig and not ok to whip out a base pipe

 

[Wizzle]

I did this before. The Azo is probably right about concentration because you definitely don't want acetone on the filter.

 

[any major dude]

4mg JWH-018, 8mg JWH-073, 8mg JWH-200, & 12mg JWH-250 were dissolved in 2mL ethanol, heated and agitated into solution. Using a metered pipette, the solution was removed from the boiling flask and 0.5mL was applied to 4 pall mall's. They were left to dry for an undetermined, but relatively short amount of time. The top of the cigarettes was slighly yellow (as was the EtOH solution) but there was no change to the taste of the smoke. Not as effective as a base pipe, but effective nonetheless. Unfortunately the color on the cigarettes makes it slightly less stealth. But most places people aren't going to notice or care if your smokes look slightly odd.

 

[TheAzo]

If your JWH's are yellow, they're impure (JWH-200 may be slightly yellow when pure - not sure).

If you're getting it from the place i assume you are (the place everyone knows about in asia, which sells all 4 of those chems), their 073 is absolutely disgusting, but you can clean it up with very little loss fairly easilly:

Put it into a small vial, and add 1-2ml of everclear per gram of JWH-073, cap, shake, and observe that the alcohol is piss yellow and the 073 already looks cleaner. Let it sit someplace warm for a little while, shake it again, then throw it into the freezer until it is cooled to freezer temperature (half hr or less, since it's a tiny vial). Remove the liquid with an eyedropper.
Repeat until your JWH-073 is a beautiful white, and then leave the vial uncapped in a warm place until the ethanol evaporates completely.

Evaporate the alcohol to get an infinitesimal amount of JWH-073 and some sticky yellow napthoyl-god-knows-what.

This does not work with JWH-018, as it's more soluble in ethanol. This tek requires that the JWH be insoluble in cold ethanol (while the yellow shit dissolves completely in even cold ethanol - the only reason you need multiple washes is to rinse out the dirty ethanol), which is the case for 073, but not 018.

 

[any major dude]

My 073 isn't really yellow, more of a slight off white-tan-beige color. Assumed there was probably some impurity as when dissolving it or 018 alone in ethanol white flakes would appear shortly before everything went into solution. The 018 is an even lighter color, though I assume not completely pure. the 250 is a very clean bright white and the 200 is somewhat yellowish. And yeah, i got it from there

And as anyone who's gotten cigarettes wet and then dried them out knows, they aren't going to look like they did before hand, even if you evaporate only pure H2O off entirely. I assume some stuff in tobacco is going to be soluble in whatever jwh's are, so putting that liquid on cigarettes is going to make your cigarettes look somewhat odd.

 

[atara]

It has been proven that nicotine increases the absorption of THC related cannabinoids, and using this model one can hopefully infer that JWH related compounds will also be increased in bioavailability.

For what it's worth, JWH-### is basically unrelated chemically to THC. One is a compelx terpenoid, one is an N-alkyl-3-napthoyl-indole. The analogy may hold with CP-47497 or CP-55940, which are similar to THC structurally, but that series seems to have gotten less popular (I'm honestly not sure why).

 

[TheAzo]

Yeah, clean the JWH-073 if you got it from there, it's worth it. It also makes it not smell and taste like mothballs.

Out of curiosity, did you find that the mixture of the 4 JWH's provides better effects than any single one?

 

[any major dude]

For what it's worth, JWH-### is basically unrelated chemically to THC. One is a compelx terpenoid, one is an N-alkyl-3-napthoyl-indole. The analogy may hold with CP-47497 or CP-55940, which are similar to THC structurally, but that series seems to have gotten less popular (I'm honestly not sure why).

I'd imagine the extreme sensitivity to heat is one reason, and the fact that they're more expensive. One bioscience supplier whose website i frequent recommends storing the CP's at -20C. I'm certainly not paying for temp controlled shipping and would like to try CP xxxxxx, but I'd imagine it would be heavily degraded by the time it arrived. Perhaps I'll order some next winter.

Yeah, clean the JWH-073 if you got it from there, it's worth it. It also makes it not smell and taste like mothballs.

Out of curiosity, did you find that the mixture of the 4 JWH's provides better effects than any single one?

I'll probably give it a shot. It does taste ever so slightly like mothballs. All of them do actually, save 250. Could be the lack of the napthyl moiety? And yes, varying combinations have noticably different effects, and i've definitely enjoyed toying around with the ratios. Some combos are more cannabis like, others definitely similar, but also notably different. A particular favorite of mine is a 2:4:3 ratio of 073 to 250 to 200. 1:2:3:3 018:073:250:200 works quite well for a more cannabinomimetic effect. I think 250 and 073 are my favorites. Hope to see more like 250 as it lacks the napthyl group that has been fingered for possible toxic/carcinogenic effects, though I'm pretty sure the latter is somewhat dubious. Probably no worse than smoking most other smokables, and almost certainly no worse than cigarettes, IMHO.

 

[Tilex]

For what it's worth, JWH-### is basically unrelated chemically to THC. One is a compelx terpenoid, one is an N-alkyl-3-napthoyl-indole. The analogy may hold with CP-47497 or CP-55940, which are similar to THC structurally, but that series seems to have gotten less popular (I'm honestly not sure why).

Oh, I know the indole / synthetic indole alkaloids are completely unrelated as far as structure, but one could (possibly) infer that because they have effects on the same receptors that at least some of the metabolism enzymes are shared, thus potentiated by the same means. Just an inference, not fact as far as these interesting chemicals go.