Violenza666
Bluelighter
How exactly does it work to potentiate? Does it potentiate if you have already dosed and are intending to re dose? Please tell me about your experiences... I did look around but did not find the answers I am looking for.
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BDD Moderators: Keif’ Richards
Tagament and opiates and redosing......
- Thread starter Violenza666
- Start date
ro4eva
Bluelighter
I've never tried tagament but I can tell you that for Oxycodone which is metabolized by CYP2D6, Bupropion (Wellbutrin / Zyban) increased the length of the high for me (it's a potent CYP2D6 inhibitor).
More info - http://en.wikipedia.org/wiki/Bupropion
For methadone and xanax (CYP3A4 substrates), I use a nutritional supplement (you can buy a bottle for $10 at any herbal supplement shop) called Quercetin (a potent CYP3A4 inhibitor) and it works really well, well, actually too well. Be careful with this stuff. I knocked myself out a couple of times.
More info - http://en.wikipedia.org/wiki/Quercetin
More info - http://en.wikipedia.org/wiki/Bupropion
For methadone and xanax (CYP3A4 substrates), I use a nutritional supplement (you can buy a bottle for $10 at any herbal supplement shop) called Quercetin (a potent CYP3A4 inhibitor) and it works really well, well, actually too well. Be careful with this stuff. I knocked myself out a couple of times.
More info - http://en.wikipedia.org/wiki/Quercetin
Here's a great doc all about opiate potentiation it's a good tool, http://www.opioids.com/opiates/index.html
1. A dose of Tagamet an hour before a hydrocodone/oxycodone session will make the drug last longer and have a better effect. Antacids should be taken at least 45 minutes after the Tagamet otherwise absorption of the Tagamet will be impaired. Grapefruit juice also has the same type of impact on liver enzymes; use a Maalox chaser to neutralise any systemic acidification effect from the grapefruit juice. Tagamet should not be taken with codeine because it impairs the metabolism into morphine necessary for it to have any real effect.
you can plug in most opiate/oids with the hydrocodone/oxycodone
1. A dose of Tagamet an hour before a hydrocodone/oxycodone session will make the drug last longer and have a better effect. Antacids should be taken at least 45 minutes after the Tagamet otherwise absorption of the Tagamet will be impaired. Grapefruit juice also has the same type of impact on liver enzymes; use a Maalox chaser to neutralise any systemic acidification effect from the grapefruit juice. Tagamet should not be taken with codeine because it impairs the metabolism into morphine necessary for it to have any real effect.
you can plug in most opiate/oids with the hydrocodone/oxycodone
Violenza666
Bluelighter
Thanks alot for that link I greatly appretiate it! xoxox
I have a high tolerance to opiates (having been on Fentanyl, Oramorph, buprenorphine) and now on 20mg daily Oxycodone slow release, 6x 5mg OxyNorm Fast acting and 10mg Diazepam... my question is - how to get high? I'm used to these drugs and can't keep upping them (I'm a chronic pain sufferer). I am slight, 8.5 stone, 5ft6 inches and a girl. I want to enjoy these sometimes - as my life is SHIT since getting ill with pain. What's the best thing to do? I drink grapefruit juice, quinine sulfate, eat avacados.... what else? Do I have to take more - and if so, for a party night for instance, what would be a safe amount of Oxy for me to take?? I have a HIGH tolerance...!!!!