Synthroid (levothyroxine) and cocaine, any interactions?

[Mr. A]

Hi I'm Mr. A and I'm new to bluelight. Actually this specific question is what brought me here in search of someone knowledgeable enough to answer my question. I'm really not a heavy user of any particular substance. I drink alcohol maybe 5-10 times a year, coke 2-5 tops and use psychedelics such as psilocybin, lucy or mesc about 5(sorry for the brief drug use description, trying to avoid ridicule).

Anyways I was recently diagnosed with hypothyroidsm and have been prescribed synthroid which is a synthetic replacement for thyroid hormones. I've read that synthroid is somehow a derivative from cocaine in a way or somehow synthesized from it, not sure if that's correct but I take this medication daily in the morning. I figured if I were to use any substance whatsoever I'd do it in the evening to lessen the chance of any possible complications.

Would using coke interact with this medication? If you have any knowledge about the above said substances such as alcohol, or psychadelics please inform me as well of those interactions to but the main question is if cocaine will interact with synthroid and if there's a safe way of doing it.

I would ask my doctor or pharmacist but for me to ask them how to safely use drugs is unethical and I don't want to be lectured, shut down or ridiculed for it.

It's sad that's the way things are.

 

[NeighborhoodThreat]

Mr. A, just because nobody replied to your post right away doesn't mean it is automatically okay to take a substance.

I don't see anything obvious about synthroid (levothyroxine is the generic name) being sourced from cocaine, or a derivative of cocaine.

As far as interactions go, I was about to dig up this list:

Levothyroxine Drug Interactions - Drugs.com

Cocaine is not listed, and neither are other powerful stimulants such as dextroamphetamine, methylphenidate, or methamphetamine. There do seem to be interactions between it and the various antiacids, however - which is worth noting.

From what I can tell, you should fine. Since you've already done cocaine in the past, you know how dosage affects the high. I would start smaller than you usually do and work your way up.

 

[Mr. A]

Yea certain antacids can mess with absorbtion of synthroid, at least that's the information I got.

Alright cool thanks

 

[NeighborhoodThreat]

Not a problem. Just remember to start low and make sure there aren't any unlisted interactions

 

[Mr. A]

Alright thanks, I did come across an article where a Dr. was replying to a message saying there were no interactions between cocaine and synthroid but she also said she wouldn't answer how to use them safely together because of it being unethical.

A concern I did see was that it could possibly potentiate some substances similar to how an mao inhibitor would and possibly mess with absorbtion of the synthroid.

I'm mainly a psychonaut for the most part and love mycology but Idk if it's wise using something that depresses the CNS while taking synthroid daily. It might be of more concern with something stronger. I have drank with no problems so far, its just sketchy testing the waters.

Sucks a lot of doctors would look down on the questions I have

 

[NeighborhoodThreat]

Yeah it does. There are some pretty good interactions checkers online but not all of them cover all possible interactions. I'm glad you're taking it slow and exercising caution when it comes to combining your Synthroid with different recreational drugs.

Start low and work your way up to where you feel comfortable. If you have any adverse reaction, don't dose any more.

I'm going to edit the title of this thread to include the generic/chemical name of Synthroid for easier searching in the future.

 

[Mr. A]

Yea that's cool.

So I took your advice and started off slow with a small bump and it didn't really bother me. I waited about 10 minutes and tried a nice line and it definitely seemed a lot stronger then I had been used to. The intensity was almost double what it normally would be but only lasted for about half an hour. I would say BP and HR were higher then normal, it was a little uncomfortable.

Stuff was really clean though, no paranoia. The reason I made this thread was cause my buddy gave me it and said it was some really good suff, that I had to try it so I've been sitting on this for a minute. It was good but definitely was better taking caution and coming here for advice, I guess I'll give the rest away.

I didn't notice any weird reactions but it was definitely potentiated. I could actually feel the vasoconstriction becoming present which isn't normal for me. It appears it would be fine as long as you lower your dosage.

Now I get to live to fight another day lol.

 

[nicksoutherland90]

Hi I'm Mr. A and I'm new to bluelight. Actually this specific question is what brought me here in search of someone knowledgeable enough to answer my question. I'm really not a heavy user of any particular substance. I drink alcohol maybe 5-10 times a year, coke 2-5 tops and use psychedelics such as psilocybin, lucy or mesc about 5(sorry for the brief drug use description, trying to avoid ridicule).

Anyways I was recently diagnosed with hypothyroidsm and have been prescribed synthroid which is a synthetic replacement for thyroid hormones. I've read that synthroid is somehow a derivative from cocaine in a way or somehow synthesized from it, not sure if that's correct but I take this medication daily in the morning. I figured if I were to use any substance whatsoever I'd do it in the evening to lessen the chance of any possible complications.

Would using coke interact with this medication? If you have any knowledge about the above said substances such as alcohol, or psychadelics please inform me as well of those interactions to but the main question is if cocaine will interact with synthroid and if there's a safe way of doing it.

I would ask my doctor or pharmacist but for me to ask them how to safely use drugs is unethical and I don't want to be lectured, shut down or ridiculed for it.

It's sad that's the way things are.

Hi there. I would just like to let you know i was diagnosed with HYPERthyroidism and received the Iodide uptake or whatever it was to kill off part of my thyroid which took it from Hyperthyroidism to hypothyroidism (i have graves disease as well). I am on 25 mcg synthroid once a day in the morning as i sure you are as well and i am a big opiate user, but i like doin a few lines here and there with my buddies on the weekends ya know? never much just maybe an eight ball between 3 or 4 people that will last us 2 days....so were not hardcore on the powder at all. ( I use to be about 3 years ago when i was snorting an 8 ball or more a day when i received a HUGE settlement for an accident i was in when i was a kid) so anyway back to the subject.... i have been on synthroid for about 6 months now and done cocaine probably 3 or 4 times since and once i even bought two grams for myself and did it all in one night and their were absolutely no negative side effects and my synthroid still seemed to work just fine. I dont think you'll have a problem. As far as psychedelics and what not idk i just smoke my pot, eat my oxys, and a little powder here and their...hope this was some kind of help

 

[Mr. A]

Thanks, they started me on 112 mcg and might be uping my dosage next week, i have no idea why so much. I need to talk to my doc tho because I think there might be something else going on as well, possibly adrenal or hypothalamus, I'm leaning more towards adrenal since how my libido was out of whack for so long but the thyroid can do that as well since they work so closely together.

I dont think it's pituitary because my tsh was up to 8 with my thyroid not producing which it should be. Pretty sure my t4 was fine but my t3 was down so somehow it's not converting properly. That would mean hypothyroid since it's not doing its job but I think there's something else going on here that doesn't meet the eye because this synthroid medication doesn't agree with me all to well either and I feel weird fluctuations all day like tightness and looseness in my jaw, like muscoloskeletal stuff, feels weird man.

Ever since this shit started last year I went from 160lbs doing mma to 240lbs now, the weights finally going down since I'm getting help but it took a long time to get insurance and i had some weird symptoms going on for a loooong time. So I may have something else going on that caused it to be unpleasant

*EDIT*
You know what just crossed my mind as weird is you said you had hyperthyroidsm and had it nuked so its not working anymore and your only using 25 mcg's you said to be where you should, I've only been on this medication for a month and a half and my starting dose is 112 mcg's.

Today i actually skipped my dose and I'm feeling much better, to be honest i haven't been feeling all that great to begin with. I think my dosage is way to high. I go back for my 6 week check up in ten days for them to adjust my dosage. Maybe I'm taking to much synthroid.

 

[a5l6o5n2]

Regarding Synthroid and other drug interactions, some internet sites say it should not be taking with diazepam or certain ssri's specifially, prozac. I take both drugs daily (aswell as suboxone, guanfacine [alpha blocker] and ritalin/adderall). My doctor didn't mention any interactions between them but I'm wondering if their is and if so what side effects are their to be expected.

I'am also A bit worried that taking an alpha blocker with synthroid and stimulants together might be putting too much pressure on my heart. BTW, my thyroid gland has completely stopped working, so the synthroid must stay. Any advice or precautions I should be aware of?

Thanks.