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Synthetic psilocybin - thoughts?

Uncle Robert

Uncle Robert

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A friend says he can get hold of synthetic psilocybin which apparently looks like tiny compact dark clumps.

Has anyone used it before, how did it compare to bog standard shroomage?
 
Synthetic psilocybin = 4-AcO-DMT

(actually technically 4-HO-DMT (I think) but 4-AcO-DMT is way more common and is converted to psilocybin (or is it psilocin?) in vivo anyway)

*prepares to be slapped down by chemistry bods for the previous sentence*

It's the bizniz %)

Comes as a greyish-brown powder and is widely available from non-UK vendors. Cheap too. Compares very favourably to mushies. I might even go so far as to say I prefer it as it's more predictable and lacks the risk of squirmygut and general weird physical issues that can sometimes mar the shroomy experience.
 
Shambles said:
Synthetic psilocybin = 4-AcO-DMT

(actually technically 4-HO-DMT (I think) but 4-AcO-DMT is way more common and is converted to psilocybin (or is it psilocin?) in vivo anyway)

*prepares to be slapped down by chemistry bods for the previous sentence*

It's the bizniz %)

Comes as a greyish-brown powder and is widely available from non-UK vendors. Cheap too. Compares very favourably to mushies. I might even go so far as to say I prefer it as it's more predictable and lacks the risk of squirmygut and general weird physical issues that can sometimes mar the shroomy experience.
Click to expand...

Schveeet thanks for the actual name. I like the predictability, with shrooms it's just a matter of munching down on that scientific unit a palmful.

Yeah the price is appealing too.

I'll get reading through that thread.
 
How do us non-American folk pronounce said chemical? Is it silo-sigh-bin, or perhaps sill-ossy-bin? None of the above?
 
I havent tried it so my opinion is worthless. However it sounds a horrendous concept to me.

How does the toxicology compare to the proper stuffs?

curious_24 said:
How do us non-American folk pronounce said chemical? Is it silo-sigh-bin, or perhaps sill-ossy-bin? None of the above?
Click to expand...

^ that


Also, I have never found shrooms unpredictable in any way
 
I pronounce it "silly psy bin". Or "sillo sigh bin" if pushed for coherency.

Marmalade said:
I havent tried it so my opinion is worthless. However it sounds a horrendous concept to me.

How does the toxicology compare to the proper stuffs?
Click to expand...

As far as I know it's identical in every way. It's not "fake" psilocybin it's simply pure psilocybin. Kinda like how synthetic DMT is the same as extracted DMT only purer. Ditto synthetic mescaline.
 
Shambles knows the score.

Had it once, a few years back after a night at Sankey's (I was trying to be sociable). It was a gift, and I remember watching the sun rise through a mate's fifth-storey window and feeling... well, perfect.

Great drug.
 
Is one of those drugs I don't think it's possible not to <3

Should be on the NHS. And actually might be at some point. Prof Nutt has been campaigning to get it in trials for depression and has already been tested and shown to be effective for patients with terminal illnesses who are struggling to come to terms with the inevitible.

Try it. You will <3 it.

/peer pressure
 
Shambles said:
(actually technically 4-HO-DMT (I think) but 4-AcO-DMT is way more common and is converted to psilocybin (or is it psilocin?) in vivo anyway)

*prepares to be slapped down by chemistry bods for the previous sentence*
Click to expand...

*actually technically 4-PO-DMT (psylocybin), which is converted to 4-HO-DMT (psilocin) in the body. %)

I like 4-HO-MET (metocin!) alot. Very similar to mushrooms.
 
Shambles said:
I pronounce it "silly psy bin". Or "sillo sigh bin" if pushed for coherency.



As far as I know it's identical in every way. It's not "fake" psilocybin it's simply pure psilocybin. Kinda like how synthetic DMT is the same as extracted DMT only purer. Ditto synthetic mescaline.
Click to expand...
ahh, didn't expect that. In that case, I'd love to try it to compare. Just looked at the wiki page and saw there are various differing opinions on the comparison of effects.
 
^ Ya. Is a real gem of a drug. Would like to sample some of the near-relatives too sometime but I get the impression that they're all broadly similar to mushies. Bordering on indestinguishable if 4-AcO-DMT is anything to go by.

Acid4Blood said:
*actually technically 4-PO-DMT (psylocybin), which is converted to 4-HO-DMT (psilocin) in the body. %)

I like 4-HO-MET (metocin!) alot. Very similar to mushrooms.
Click to expand...

Meh. OH HO. POOP HOOP POPO. POOH HO' HOOP PO', PO' HO'. It's all just powdered swerlz to me %);)=D

(thanks for the correction though)

Where does 4-AcO-DMT fit in then, A4B? Isn't that converted to psilocin upon ingestion? Is a pro-drug for it, no? At least that's what I recall getting into a debate about in the PD thread. I pointed out that it's highly effecive IV and a couple of the chemistry bods (who had never IV'd it, naturally) said I must've been imagining it cos it's a prodrug and needs to be metabolised into psilocin in order to cause swirlyfuntimes. Guess who was right ;)
 
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^ Aye, 4-AcO-DMT is also converted into 4-HO-DMT in the body.
Haven't tried it yet actually. Might get a sample next time I'm ordering from vendor.

Anyone notice any major differences between 4-AcO-DMT & 4-HO-MET ? Which do people prefer?
 
[edit]
Found this ace site for greetings cards ages ago ... a number of good drug related cards ... as well as political/dictator ones ... not really big on valentines, but I kinda liked a lot of these for originality.


flat,800x800,070,f.u1.jpg
 
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^ =D<3=D

Acid4Blood said:
^ Aye, 4-AcO-DMT is also converted into 4-HO-DMT in the body.
Click to expand...

Wonder how the "It's only a prodrug" theory ended up then. If it's merely a thing to be converted to a different thing in order to have an effect it shouldn't work instantaneously when IV'd. Nothing could be further from the truth! Is uberpotent and very similar to IV DMT in terms of effect. Although I've never IV'd DMT itself it certainly felt like I'd just shot up an IV DMT trip report and folk who have IV'd both say the difference is neglible between the two. This makes it doubly intriguing as it seems to closely mimic two of the finest drugs on Earth depending on your ROA. This is a Good Thing %)
 
^ Interesting indeed!

So basically you're saying:

Oral 4-AcO-DMT = mushroom experience
IV 4-AcO-DMT = DMT experience

Not that I'm ever going to start IV'ing tryptamines but interesting none-the-less! %)
 
That is precisely what I'm saying. And sticking to. Not just me saying it either - discussion took place here over in the IV 4-AcO-DMT subthread over in PD if anybody's interested. Features me doing a live TR of my first attempt at injecting it.

As for IV tryptamines, is it not just extracted stuffs that are iffy? "Pure" versions don't have the same risks associated afaik. Not that I'm suggesting you or anybody else should develop a new hobby :D
 
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Shambles said:
As for IV tryptamines, is it not just extracted stuffs that are iffy? "Pure" versions don't have the same risks associated afaik.
Click to expand...

I'm sure IV'ing pure Tryps is grand! :) I just meant I'm not going to start IV'ing anything, ever! =D That's not to say I wouldn't let someone else do it for me! %)
 
Hahahahahahaha! You have no idea how common a position on the IV question that is, A4B ;)

I actually used to fund large parts of me addictions by freelance "doctoring" for hire =D

(admittedly mostly for folk who were just shit at it/had no veins left but also in some cases catering to the "interested amateur not seeking to turn pro" market)
 
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