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Synthetic cannabinoids worthwhile vs. Cannabis

Are synthetic cannabinoids worth taking if you have access to good cannabis?

  • No

    Votes: 34 50.7%
  • Yes, namely ...

    Votes: 33 49.3%

  • Total voters
    67
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No.

Does meperidine feel exactly like opium tar? Do No-Doz synthetic caffeine pills feel just like coffee?

Is any synthetic flavor superior to its naturally occurring equivalent? The effect of natural marijuana is just so much richer and full of subtle nuances, due to the blend of many different cannabinoids. No one chemical, acting alone, can recreate all of the enjoyable effects of this plant.

I am all for sprinkling a tiny bit of JWH-073 on some medium grade bud, though.
 
^ I agree that weed gives a richer and more nuanced experience, and for that reason I prefer it to the two JWH- compounds I've tried (-018 and -073).

However I still found giving those synthetic cannabinoids a taste worthwhile since I got to experience a different take on "being stoned" with each one. I feel that these impressions have subsequently influenced my cannabis highs in turn.

Doubt I'll make my use of the synthetics a regular thing since I just don't enjoy them as much, plus the possible health consequences worry me a little. I didn't, however, find either of them anxiety-inducing in the slightest.
 
^ Oh yes. It definitely is un-boring to try a new flavor of that feeling called 'stoned', that I never imagined before might exist. 073 had absolutely no anxiety or effects on my language ability. But it was missing a few key fun parts too that I always look forward to when I have a toke. I don't know if I quite find 018 recreational. In any case its recreational value is far below doob or 073.
 
Voted No. Much rather weed; thats said JWH-018 is the one I used the most (and only one I still have) and the tiny doses were a pain to measure out. I could smoke either weed or JWH018 right now, but I would without a question, smoke the weeeed :)
 
I voted yes, but I didn't read the thread first. Synthetic cannabinoids are worthwhile but if I had a reliable, cheap source for dank weed I would most likely not use a synthetic alternative, unless I needed to pass a drug test or something. Like a few people have said, I love that social activity of smoking and even just the act of smoking in general.

JWH-018 is great and is very economical so it is what I am using at the moment. I like the low doses and how clean feeling the high is. It doesn't last as long unfortunately but it doesn't give me that fogginess/lethargy of weed once it wears off. It doesn't have that body high aspect for me, mainly just the head. Tolerance is a bitch too, it builds too fast plus possibility of unknown negative reactions is a downer.
 
yeah, i have both right now, and i've been smoking more weed, but lately my lungs haven't felt so good, and synthetics are orally active, and easy to pop into a pill.

taking them orally doubles the active time, and makes the high much more relaxed and euphoric for me atleast.

so planning on taking a break from weed this weekend and popping 073 pills.
 
I vaporized 9mg of jwh-073 about three hours ago... first time trying a jwh-xxx... and first cannabinoid high in months.... and wow!!

it definitely seemed a lot more crisp, meditative, and clear than my marijuana highs.... also a lot less pushy mentally... i didn't get that typical flow of randomly-connected thinking that i often would get with marijuana

after this trial, it seems like jwh-073 is better for my needs than pot was... very very impressed!
 
No.

Does meperidine feel exactly like opium tar? Do No-Doz synthetic caffeine pills feel just like coffee?

Is any synthetic flavor superior to its naturally occurring equivalent? The effect of natural marijuana is just so much richer and full of subtle nuances, due to the blend of many different cannabinoids. No one chemical, acting alone, can recreate all of the enjoyable effects of this plant.

I am all for sprinkling a tiny bit of JWH-073 on some medium grade bud, though.

i would say most synthetic and semi-synthetic Opes are better then the Natural ones

your example of meperidine is correct but thats cuz meperidine is a funny lil opioid

in general Semi and fully synthetic Opes are better then the two natural ones--codiene morphine

IMHO, of course
 
^There's an interesting question in this. Does the the typically "messy" broad spectrum receptor activation of natural chemical psychoactives tend to have superior qualitative effects compared to the typically more specific effects of single-chemical synthetic counterparts? Why should broader activation be richer instead of muddled, conflicted, and chaotic? Why should specific activation be cleaner instead of just awkward? How should we weigh the apparent natural-over-synthetic bias in interpreting reports supporting either stance?
 
JWH-073 was surely a worthwhile substitute.

JWH-018 only managed to give me extreme dizziness and debilitation.
 
I voted No although my answer is somewhere in between. I think trying them a few times just for the novelty isn't going to cause any problems but there are potential health concerns. Namely, they may be carcinogenic. To what degree is unknown but the prospect scares me a bit to be honest.

Because of this, using them as a replacement for cannabis is a bad idea IMO which is why I put no.

If there were no health concerns I still would prefer good weed as it has a great taste and classic effects but I would definitely use the synths sometimes as they are very cheap and convenient/stealthy. They also have some unique effects which can be desirable at times.
 
we have random drug tests at work. These synthetics are wonderful if you get the right suppler. it's a lot of trial and error but i got it now and i like it!
 
An enthusiastic Yes!
JWH-018 (particularly) and 073 (to a lesser degree) have been remarkable spiritual aids. I've been into places of mind that I cannot even dream of on bud.

As I use them sparingly (once/twice a month) I have zero tolerance and 2-3 mg is a full blown experience. I would choose Synthetic cannabinoids any day over bud. Also as I'm mildly asthmatic, I have some difficulties in inhaling even mild marijuana, while synths vaporized on my lighbulb are just a whiff of smoke, totally benign!

[And, as it is, I do no buy into the theory of potential evil metabolites of JWH-018, and I have been following the discussions on ADD closely.]
 
I've never been a huge marijuana smoker, but lately I've fallen really hard for one of the JWH's, particularly JWH-250. I originally purchased it because of the non-napthalene ring, thinking it less prone to cancerous metabolites. All I can say is wow. I'm sure I used much more than most people here, as my method was basically smoke until I feel unable to function, really. At the beginning, I estimate it might have been 10-20mg per dose, but at the end of my run with it I think I ended up with 50-100 mg + per session :|

So I voted yes. It also seemed to be a very different high than weed, although that may have been due to my high doses
 
while the cannabinoid receptor system appears to be VASTLY more tolerant of overdose or chronic administration without negative side effects (compared to dopaminergic stimulants or opioid depressants that can kill you in a single blow), i must warn people to try not to follow in your research.

knocking your cannabinoid receptors with a roundhouse kick to the face like high doses of these potent JWH compounds has been known to cause very peculiar side-effects. see various threads in CD in which "k2 spice ruined my life" or similar.

100+mg doses of these compounds is similar to ingesting an ounce or two of hash. sure, it probably won't kill you like a bunch of opium would, but long-term tolerance effects have not been studied on this receptor system. many people notice that "rebound nausea" that can be likened to the exact opposite of the munchies. as in, your appetite control system gets completely out of whack and you are unable to keep any food down because your body is simply not able to regulate itself anymore.

edit: i vote yes, because i am a scientist at heart and the opportunity for use to explore nuances of selective agonists is very appealing to me. however they require much care for use, because as others have stated, they can build up a gigantic tolerance that can destroy the magic of plain cannabis.
 
Yes, especially high doses of jwh073 for me. Extremely psychedelic, no anxiety, somewhat short lived but for that first half hour or so...yowza... another world. I'm talking about 4 big hits smoking about the size of a safety match head (per person, we each do it in our own pipes).

My lady and I both agree, excellent for sex.
 
Is anyone aware of reports by users of degrading CP? I havn't seen any, just people debating how low a temperature they should store them at, and people saying they had no problems.
I had CP 55,940 for a while, and I kept it in the freezer for like 6 months... It was still active after that time, although I think I may have received the product somewhat degraded/impure because it took quite a bit more than 250mcg-1mg for a nice high. I would smoke like 5mg.

Just keep it in the freezer in an airtight glass mason jar with silica gel. And when you take it out of the freezer, be sure to wait at least 30 minutes-1 hour before opening it so that moisture doesn't get into the jar and ruin your product.

Wikipedia states that CP 55,940 provides "a greater reaction to opiates in exposed mice". Is this a possible opiate potentiator?
 
while the cannabinoid receptor system appears to be VASTLY more tolerant of overdose or chronic administration without negative side effects (compared to dopaminergic stimulants or opioid depressants that can kill you in a single blow), i must warn people to try not to follow in your research.

knocking your cannabinoid receptors with a roundhouse kick to the face like high doses of these potent JWH compounds has been known to cause very peculiar side-effects. see various threads in CD in which "k2 spice ruined my life" or similar.

100+mg doses of these compounds is similar to ingesting an ounce or two of hash. sure, it probably won't kill you like a bunch of opium would, but long-term tolerance effects have not been studied on this receptor system. many people notice that "rebound nausea" that can be likened to the exact opposite of the munchies. as in, your appetite control system gets completely out of whack and you are unable to keep any food down because your body is simply not able to regulate itself anymore.

Oh, I agree. I was never suggesting it was a good idea. I've actually stopped ordering it, simply because my use was getting out of control.

I checked out that thread you mentioned, "k2 spice ruined my life" and it was very interesting. I have heard of the cannabis hyperemesis syndrome manifesting in very chronic cannabis users, but never about sparse use of spice cause such profound changes. Thank you for the read :)
 
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