Substrates... Inhibitors... Inducers...

[reflekt]

So, I've recently got a nice list of substrates and their inhibitors and inducers.

But, I am a little confused. This may be a stupid question. But, what is the difference between inhibitors and inducers? They both seem like good things to make a drug better to me, based on a first impression and a non-educated one at that. I understand one makes them metabolize faster, and the other slower? I think?

Ah, dumb.

If someone could educate me without making fun, that would be lovely .

Thanks.

 

[amapola]

Inhibitors prevent the enzyme from processing substrates.
Inducers aid the enzyme in processing substrates.

Both could be used for getting you higher.

Use inhibitors to stop an active drug from getting metabolized into an inactive compound.
Use inducers to help an inactive prodrug metabolize into an active compound.

 

[Psychedelic Jay]

Inhibitors- Slows enzyme breaking down drugs. Bad for inactive prodrugs, good for already active drugs. Longer duration for already active drugs. Can stop some prodrugs from even working well.

Inducers- Enhances enzyme breakdown of drugs. Good for inactive prodrugs, bad for already active drugs. Shorter sometimes more intense duration.


You should make acquaintance with the search engine.

 

[capRx]

^^ What they said. I explained it, but edited because its just redundant

 

[reflekt]

Thanks guys, much help.

Tried searching, not as much help as provided here!

 

[amapola]

^Not as efficient help perhaps...