Since you've been on for about 6 months you will have a decent build up of bupe in your system. But you will probably start feeling the mental WDs at your first missed dose. Physical WDs will start anywhere from 24 to 72 hrs after your last dose depending on many factors. Your usually dosage size, how fast/slow you metabolize the bupe, etc.. But I will tell you this, being that long till your next refill you will experience WD at some point before it. Also the WD will likely be a nasty one since you know that you will be getting & using more. Just a bad setup for WDing in. I've heard lyrica can make opie WDs much more bearable, same with opiate based diarrhea meds. But I've never tried either, when I used to fuck my sub script up & ran out early I'd go straight for the strong shit rather than deal with WD. After some really bad WDs thanks to my crazy usage I now take my subs as prescribed & have had much more success with my recovery since.